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See Latest ArticlesLysosomal recycling terminates CD1d-mediated presentation of short and polyunsaturated variants of the NKT cell lipid antigen alpha-GalCer
Proceedings of the National Academy of Sciences of the United States of America, 07/02/09
Bai L et al. - These findings provide a common cell biological explanation for the decreased stimulatory properties of short and polyunsaturated alpha-GC variants. They also suggest that direct lipid displacement is a potent mechanism underlying highly dynamic lipid exchange reactions in the lysosomal compartment that shape the repertoire of lipids associated with CD1d.
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