Internal Med Medical News about antihypertensive therapy;improving outcomes

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Improving outcomes in hypertensive patients: Focus on adherence and persistence with antihypertensive therapy
The Journal of Clinical Hypertension, 06/25/09

Elliott WJ et al. – A review on outcomes in hypertensive pts reports improved outcomes with a focus on adherence and persistence with antihypertensive therapy.

Methods

Review on outcomes in hypertension

Results

Blood pressure (BP) control rates among treated pts in actual clinical practice are less than optimal despite effective BP control reducing risk of cardiovascular events in hypertension
Costs of drugs and medical care are key but difficult to estimate both in clinical trials and general clinical practice
Drug-taking behavior—adherence and persistence with antihypertensive regimens—influences BP control rates
Rates vary greatly among antihypertensive classes based on many factors affecting pt adherence and persistence, including drug efficacy and tolerability
Medications with fewer adverse effects associated with increased adherence and lower discontinuation rates
Widespread use of these drugs (and generic or low-cost formulations) may lead to better long-term BP control and fewer cardiovascular events

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