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See Latest ArticlesThe Association Between Dementia and Long-Term Use of Benzodiazepine in the Elderly: Nested Case-Control Study Using Claims Data
American Journal of Geriatric Psychiatry, 07/01/09
Wu CS et al. - Findings suggest that long-term use of BZDs is associated with an increased risk for dementia, but the underlying mechanisms remain unclear, and further investigations are needed. Long-term use of BZDs should be avoided among the elderly, who may be at a higher risk for developing dementia, in addition to other health problems.
Methods- Cases (N = 779) were patients who were identified with dementia at least two times in their outpatient claims.
- They were individually matched to six comparison subjects (N = 4,626) based on age and gender.
- BZD usage (average dosage per year, average days per year, and cumulative dose and periods) and potential confounding comobidities, including cardiovascular and psychiatric diseases.
- Subjects with dementia had higher cumulative dose, longer duration of BZDs exposure, and more likelihood to be long-term BZDs users.
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Today in Clinical Pharmacology...keeping you current
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Treatment with alpha-lipoic acid reduces asymmetric dimethylarginine in patients with type 2 diabetes mellitus
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Today in Geriatrics...keeping you current
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Aging affects the mental simulation/planning of the “rising from the floor” sequence
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Effect of Raloxifene on Serum Lipids for Type 2 Diabetic Menopausal Women with or without Statin Treatment
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Today in Psychiatry...keeping you current
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Health-related quality-of-life profiles in nonalexithymic and alexithymic subjects from general population
Journal of Psychosomatic Research, 12/11/09
Catatonia: Clinical Aspects and Neurobiological Correlates
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Psychopharmacological Treatment for Cognitive Impairment in Survivors of Traumatic Brain Injury: A Critical Review
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