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The renin-angiotensin system: an old, newly discovered player in immunoregulation
Transplantation Reviews, 07/02/09
Geara AS et al. - Experimental studies have found that RAS blockade decreases the histologic lesions of chronic allograft nephropathy but can enhance acute graft vasculopathy. Although the blockade of RAS has been commonly practiced to reduce posttransplantation hypertension, proteinuria, and erythrocytosis, however, its role in prolonging graft survival is not well established.
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