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Cardiovascular involvement in primary systemic vasculitis
Best Practice & Research: Clinical Rheumatology, 07/01/09

Mukhtyar C et al. – A review summarizes data available for the effect of primary systemic vasculitis on cardiovascular endpoints (coronary artery disease, congestive cardiac failure, hypertension, aortic aneurysm) in all age groups. A discussion is presented of the interplay between activated endothelium, autoimmune mechanisms and treatment factors to produce a direct insult or increased atherogenic potential of primary systemic vasculitis. Recommendations for cardiovascular endpoints are offered.

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