Most Viewed Abstracts
1. Report Shows Shift in Starting Salaries for Physicians 2. Recommendations on the use of 18F-FDG PET in oncology 3. Gene expression signatures, clinicopathological features, and individualized therapy in breast cancer 4. AHA Guidelines on Cardiac CT for Assessing Coronary Artery Disease 5. Rapid correction of low vitamin D status in nursing home residents
Top Ten Searches
etanercept hypertension chf antiphospholipid fibrosis mrsa scid renal cell rickets counterpulsationYour Article Summary
Treatment of fibromyalgia syndrome with gabapentin and pregabalin – A meta-analysis of randomized controlled trials
Pain, 06/19/09
Häuser W et al. - Study concludes that the usage of gabapentin (GPT) and pregabalin (PGB) can be considered for the treatment of pain and sleep disturbances in FMS patients. Because of some dose-dependent relevant side effects of both drugs the treatment should start with low dosage and then increased slowly with small dosages.
Methods- Aim of this systematic review and meta-analysis was to determine the clinical relevance of GPT/PGB for the treatment of FMS
- MEDLINE, PsycINFO, SCOPUS, www.clinicaltrials.org, the Cochrane Library (through October 2008), and the reference sections of original studies on GPT/PGB in FMS were searched
- Randomized controlled trials (RCTs) on the treatment of FMS with GPT and PGB were analyzed
- 6/127 RCTs studying 2422 subjects on treatment with GPT (1 study) or PGB (5 studies) and 1056 subjects on placebo with a median treatment duration of 11wks were included
- Strong evidence for a reduction of pain, improved sleep and improved health-related quality of life (HRQOL) but not for depressed mood
- There was strong evidence for a non-substantial reduction of fatigue and of anxiety
- The external validity of the studies was limited because pts with severe somatic and mental disorders were excluded
Today in Clinical Pharmacology...keeping you current
Receive free subspecialty "5-minute updates" via email
Novel Therapies for Pemphigus Vulgaris: An Overview
Drugs & Aging, 09/21/09
Antithrombotic medication for stroke prevention
Expert Review of Cardiovascular Therapy , 10/20/09
Osteonecrosis of the jaw correlated to bisphosphonate therapy in non-oncologic patients: Clinicopathological features of 24 patients
Journal of Rheumatology, 11/09/09
Today in Psychiatry...keeping you current
Receive free subspecialty "5-minute updates" via email
An algorithm for the pharmacological treatment of depression
Acta Psychiatrica Scandinavica, 11/04/09
Is Monotherapy as Good as Polypharmacy in Long-Term Treatment of Bipolar Disorder
Canadian Journal of Psychiatry, 11/16/09
Cardiometabolic Risk of Second-Generation Antipsychotic Medications During First-Time Use in Children and Adolescents
JAMA, 10/28/09
Today in Rheumatology...keeping you current
Receive free subspecialty "5-minute updates" via email
Treatment of polymyalgia rheumatica
Archives of Internal Medicine, 11/10/09
Osteonecrosis of the jaw correlated to bisphosphonate therapy in non-oncologic patients: Clinicopathological features of 24 patients
Journal of Rheumatology, 11/09/09
Effect of biomagnetic therapy versus physiotherapy for treatment of knee osteoarthritis: A randomized controlled trial
Journal of Rehabilitation Medicine, 11/20/09
Sponsor
Article Search
Sponsor
Sponsor


See Latest Articles


