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Low-grade gliomas in older patients
Cancer, 07/01/09
Schomas DA et al. - The retrospective series of older patients suggests that intracranial LGG in this age group behaves aggressively. Pathologic sampling error failing to recognize higher-grade tumors does not seem to account for these poor outcomes. Aggressive management with maximally safe resection followed by adjuvant therapy should be strongly considered.
Nadia N. Laack, 07/24/09
| This review looks at a rare condition in older adults. Typically survival for low-grade gliomas is 5-7 years. These outcomes suggest low grade gliomas behave aggressively in the elderly (more similar to grade 3 or higher grade tumors) and likely should be treated as such. We recommend adjuvant radiotherapy with or without temozolamide chemotherapy after maximally safe resection. |
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