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Nahas R et al. - Changes in HbA1c values are most often used to evaluate hypoglycemic effects. It is important to consider that the life span of a red blood cell is 120 days. Therefore, studies investigating diabetes management should involve HbA1c measurements and should be of at least 4 months’ duration. Most of these trials were of insufficient duration to evaluate this outcome. None of the research examined has addressed the potential effect of CAM interventions on cardiovascular outcomes. This is important because better glycemic control might not always lead to real-world clinical benefits. It is also important because some interventions can improve other cardiovascular risk factors. Overall, there is a paucity of research evaluating CAM therapies that are commonly used to treat type 2 DM. This should be a high priority for CAM researchers and funding agencies.


   

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