Most Viewed Abstracts
1. Report Shows Shift in Starting Salaries for Physicians 2. Recommendations on the use of 18F-FDG PET in oncology 3. Gene expression signatures, clinicopathological features, and individualized therapy in breast cancer 4. AHA Guidelines on Cardiac CT for Assessing Coronary Artery Disease 5. Rapid correction of low vitamin D status in nursing home residents
Top Ten Searches
etanercept hypertension chf antiphospholipid fibrosis mrsa scid renal cell rickets counterpulsationYour Article Summary
Serum urate during acute gout
Journal of Rheumatology, 06/12/09
Schlesinger N et al. – A normal serum urate (SU) level at presentation does not exclude an acute gouty attack, possibly attributed to persistence of tophi and an increased body uric acid pool. Additional studies are needed to determine the correlation between SU and the body uric acid pool as well as the relationship to timing of changes during acute gout.
Methods- Aim was to study the frequency of normal SU levels during acute gout
- Data collected from 2 randomized controlled clinical trials assessing the efficacy of etoricoxib or indomethacin for 7 days
- SU levels during acute gouty attacks were assessed
- Efficacy was similar with both agents, so both groups were combined for analysis
- 339 pts enrolled in the 2 studies; 94% male; mean age: 50.5 yrs
- At baseline, 14% of pts had a “true” normal SU (≤6 mg/dl) and 32% had SU ≤8 mg/dl during acute gout
- Baseline mean SU was 7.1 vs 8.5 mg/dl in those taking allopurinol vs nonusers
- Pts taking chronic allopurinol were more likely to have lower SU at baseline vs those not taking chronic allopurinol during the acute attack
Related Articles
Outcome Domains for Studies of Acute and Chronic Gout
Journal of Rheumatology, 10/20/09
Relevance Score: 69%
Progress in Measurement Instruments for Acute and Chronic Gout Studies
Journal of Rheumatology, 10/23/09
Relevance Score: 68%
The modern management of gout
Rheumatology, 10/08/09
Relevance Score: 66%
Acute chylous ascites mimicking acute appendicitis in a patient with pancreatitis
World Journal of Gastroenterology, 10/20/09
Relevance Score: 47%
Acute silent cerebral infarction in children with sickle cell anemia
Pediatric Blood & Cancer, 10/09/09
Relevance Score: 46%
Today in Rheumatology...keeping you current
Receive free subspecialty "5-minute updates" via email
Alendronate reduces osteoclast precursors in osteoporosis
Osteoporosis International, 12/09/09
Psychological correlates of self-reported functional limitation in patients with ankylosing spondylitis
Arthritis Research & Therapy, 12/09/09
The Use of Micronutrient Supplements Is Not Associated with Better Quality of Life and Disease Activity in Canadian Patients with Systemic Lupus Erythematosus
Journal of Rheumatology, 12/09/09
Sponsor
Article Search
Sponsor
Sponsor


See Latest Articles


