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Modulation of GnRH pulse generator sensitivity to progesterone inhibition in hyperandrogenic adolescent girls – Implications for regulation of pubertal maturation
Journal of Clinical Endocrinology and Metabolism, 04/10/09
Blank SK et al. - Hyperandrogenism is variably associated with reduced GnRH pulse generator sensitivity to P-mediated slowing during adolescence. In addition to androgen levels, insulin resistance may modulate P sensitivity.
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