Kinnunen U et al. - In a study to evaluate the effect of various chemotherapy courses on the rate of bloodstream infections (BSI) during therapy-related neutropenia, it seems that chemotherapy courses per se may have an influence on the rate of BSI during neutropenia Methods
All infection episodes of adult pts with acute myeloid leukaemia (AML) during 7 years were retrospectively analysed in a university hospital
Results
Of 182 infection episodes in 76 AML pts, 37% were BSI
Risk ratio of BSI was highest after regimens containing high-dose cytarabine and lowest after thioguanine-containing courses