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RAS gene polymorphisms, classical risk factors and the advent of coronary artery disease in the Portuguese population
BMC Cardiovascular Disorders, 07/23/08

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Freitas AI et al. - ACE polymorphisms were shown to play a major role in individual susceptibility to develop CAD. There is also a clear interaction between RAS predisposing genes and some biochemical/environmental risk factors in CAD onset, demonstrating a significant enhancement of classical markers particularly by ACE I/D and ACE11860.

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