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Effects of Six APOA5 Variants, Identified in Patients With Severe Hypertriglyceridemia, on In Vitro Lipoprotein Lipase Activity and Receptor Binding
Arteriosclerosis, Thrombosis, and Vascular Biology, 07/18/08
Print     Email This Article     Save in My Library   Free Abstract
Dorfmeister B et al. - The in vitro determined function of these apoAV variants only partly explains the high TG levels seen in carriers. Their occurrence in the homozygous state, coinheritance of LPL variants or common APOA5 TG-raising variant in trans, appears to be essential for their phenotypic expression.
 

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