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Role of NF-{kappa}B and PI 3-kinase/Akt in TNF-{alpha}-induced cytotoxicity in microvascular endothelial cells
American Journal of Physiology: Renal Physiology, 07/21/08
Print     Email This Article     Save in My Library   Free Abstract
Zhou Z et al. - PI3-kinase/Akt activation during TNF-alpha exposure may represent a compensatory anti-necrotic and anti-apoptotic pathway. The cytoprotective effects of NF-kappa-B inhibition and PI3-kinase/Akt activation may have potential implications in the treatment of endotoxemia and septic shock.
 

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