Zaccaria E et al. - MEDF have been reported in the setting of autoimmune diseases, treated with immunosuppressive drugs, in the course of HIV infection and in neoplastic diseases. An association with immunosuppression has led to the speculation that they are the result of an abortive immunoreactive process.A case is described of a patient with Sezary syndrome and a patient with multiple IgA myeloma who developed MEDF.
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