Ho HC et al. - Weekly cisplatin 30 mg/m2 as concurrent chemoradiation (CCRT) was effective in elderly nasopharyngeal carcinoma (NPC) pts, with acceptable and reversible acute toxicity following CCRT therapy Methods
Retrospective study of efficacy, toxicity, and tolerability of a multi-modal treatment strategy in stage IIB-IV NPC pts age >60 yrs with subsequent systemic adjuvant chemotherapy for systemic control
CCRT chemotherapy protocol: 8 weekly doses of cisplatin 30 mg/m2 in an outpatient setting
Adjuvant systemic chemotherapy: 4 monthly cycles of cisplatin (20 mg/m2/day) plus 5-fluorouracil (1000 mg/m2/day) for 5 consecutive days