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Article Summary

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Detection of rheumatoid arthritis bone erosions by two different dedicated extremity MRI units and conventional radiography
Annals of Rheumatic Diseases, 07/11/08
Print     Email This Article     Save in My Library   Free Abstract
Duer-Jensen A et al. - Both extremity MRI (E-MRI) units detected more erosions than conventional radiography (CR), in particular due to a higher sensitivity in metacarpal heads and carpal bones.

Methods
  • Aim was to compare the ability of two E-MRI units and CR for identifying bone erosions in RA metacarpophalangeal (MCP) and wrist joints
  • CR and two MRI examinations of 418 bones in the dominant wrist and second to fifth MCP joints of 15 pts with RA and 4 healthy controls

Results
  • In MCP joints, MagneVu visualised 18.5% of bones entirely and 71.1% were 67–99% visualized
  • In wrists, MagneVu visualised 1.5% of bones entirely, 39.8% were 67–99% visualised and 19% were not visualised at all
  • Artoscan and CR visualised all bones entirely
  • Artoscan, MagneVu and CR found 22, 19 and 15 bones with erosions in MCP joints and 66, 40 and 13 bones with erosions in wrist joints, respectively
  • MagneVu and CR had sensitivities of 0.82 and 0.55, respectively, in MCP joint bones and 0.41 and 0.14 in wrist bones
  • Specificities of CR and MagneVu were comparable
  • The MagneVu unit was particularly more sensitive than CR for metacarpal heads and carpal bones
  • MagneVu MRI and CR detected 100% and 89%, respectively, of large erosions in MCP joints and 69% and 15.8% of large erosions in wrists

 

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