Nattermann J et al. - CCR5+ T cells were highly susceptible to NKG2A-mediated inhibition of cytotoxic activity and NKG2A+ lymphocytes were preferentially attracted by CCR5 ligands induced by hepatitis C virus E2 antigen. Thus, CCR5 is likely to exert immunoregulatory effects in hepatitis C virus infection by preferentially recruiting CD8+ T cells bearing the inhibitory NKG2A receptor to the liver.