Liu MC et al. - Inhaled human insulin causes small, early and reversible changes in pulmonary function in subjects with diabetes mellitus. Baseline cellular and soluble constituents of lavage fluid were similar to those reported for nondiabetic adults. Exubera® produced no consistent clinically or statistically significant changes in total or differential lavage fluid cell counts or protein concentrations, even though Exubera®-associated changes in pulmonary function are known to be fully manifest within 12 weeks.
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