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Airway LXA4 Generation and LXA4 Receptor Expression are Decreased in Severe Asthma
American Journal of Respiratory and Critical Care Medicine, 06/27/08

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Free Abstract

Planaguma A et al. - Mechanisms underlying pathological airway responses in severe asthma include lipoxin underproduction with decreased expression of lipoxin biosynthetic enzymes and receptors. Together, these results indicate that severe asthma is characterized, in part, by defective lipoxin counter-regulatory signaling circuits.

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