Z Moldoveanu, et al. - Immunoglobulin A (IgA) nephropathy is the most prevalent form of glomerulonephritis worldwide. A renal biopsy is required for an accurate diagnosis, as no convenient biomarker is currently available. We developed a serological test based upon the observation that this nephropathy is characterized by undergalactosylated IgA1 in the circulation and in mesangial immune deposits...Conclusion: This lectin-binding assay may have potential as a noninvasive diagnostic test for IgA nephropathy
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