Coenzyme Q10; an adjunctive therapy for congestive heart failure?
New Zealand Medical Journal, 11/04/2009
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heart failure (CHF) followed for a median of 2.69 years. This is consistent with previous studies which have shown myocardial CoQ10 depletion in CHF, and correlated with the severity of the underlying disorder. Several intervention studies have been undertaken with CoQ10 in CHF, including randomized ... CoQ10 supplementation improves survival in CHF patients. CoQ10 depletion may also be a contributory factor for why statin intervention has not improved outcomes in CHF. There is an emerging evidence base in support of CoQ10 as an adjunctive therapy in CHF.
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Changes in Connexin Expression and the Atrial Fibrillation Substrate in Congestive Heart Failure
Circulation Research, 11/03/2009
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Burstein B et al. – CHF causes atrial connexin changes, but these are not essential for CHF–related conduction disturbances and AF promotion, which are rather related primarily to fibrotic
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Atrial Standstill Causing Congestive Heart Failure in a Child with Ostium Secundum Atrial Septal Defect
Pediatric Cardiology, 12/08/2009
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Congestive heart failure (CHF) may occur in the presence of significant mitral valve disease, pulmonary artery hypertension, or other diseases that lead to elevated filling pressures of the ventricles. Atrial standstill, a rare disease, was the probable cause of CHF in the 3–year–old
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Effectiveness of Public Report Cards for Improving the Quality of Cardiac Care: The EFFECT Study: A Randomized Trial
JAMA, 11/25/2009
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Tu JV et al. – Public release of hospital–specific quality indicators did not significantly improve composite process–of–care indicators for AMI or CHF.
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Cardiac Efficiency Improvement after Slow Continuous Ultrafiltration Is Assessed by Beat-to-Beat Minimally Invasive Monitoring in Congestive Heart Failure Patients: A Preliminary Report
Blood Purification, 11/13/2009
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Giglioli C et al. – In CHF patients, ultrafiltration improves not only CO, as previously reported, but also contractile cardiac efficiency and performance. The PRAM system, a
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Day-90 Acute Ischemic Stroke Outcomes Can Be Derived from Early Functional Activity Level
Cerebrovascular Diseases, 11/19/2009
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index ischemic stroke strongly predicts final 3–month disability outcome. Functioning at 1 week, supplemented by initial stroke severity and CHF history information, may provide an early outcome guide useful for patient and family counseling.
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A Pilot Evaluation of the Long-term Effect of Combined Therapy With Intravenous Iron Sucrose and Erythropoietin in Elderly Patients With Advanced Chronic Heart Failure and Cardio-Renal Anemia Syndrome: Influence on Neurohormonal Activation and Clinical Outcomes
Journal of Cardiac Failure, 11/05/2009
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combined therapy with IV iron and rHuEPO may increase Hb, reduce NT–proBNP, and improve functional capacity and cardiovascular hospitalization in elderly patients with advanced CHF and CRAS with mild to moderate renal dysfunction.
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Rationale and design of Ferinject Assessment in patients with IRon deficiency and chronic Heart Failure (FAIR-HF) study: a randomized, placebo-controlled study of intravenous iron supplementation in patients with and without anaemia
European Journal of Heart Failure, 11/02/2009
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Anker SD et al. – This study will provide evidence on the efficacy and safety of iron repletion with ferric carboxymaltose in CHF patients with ID with and without anaemia.
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Is There a Difference Between Patients With Peak Oxygen Consumption Below 10 mL/kg/min Versus Between 10 and 14 mL/kg/min? Does the Grey Zone Really Exist
Transplantation Proceedings, 11/16/2009
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exercise testing is an important component of evaluation when orthotopic heart transplantation (OHT) is considered for chronic heart failure (CHF) patients. Patients with VO2max between 10 and 14 or <10 mL/kg/min are at similar risk of death.
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Pressure-Volume Relationship During Dobutamine Stress Echocardiography Predicts Exercise Tolerance in Patients With Congestive Heart Failure
Journal of the American Society of Echocardiography, 12/09/2009
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Ciampi Q et al. – In patients with CHF, impaired noninvasively assessed myocardial contractility is related to impaired systolic and diastolic function, higher BNP levels, and poorer
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