Top antiphospholipid Articles in Internal Medicine

Common infectious agents prevalence in antiphospholipid syndrome
Lupus, 11/05/2009

Zinger H et al. – This novel finding suggests that these infections might be associated with antiphospholipid syndrome. As autoimmune diseases and, in particular, antiphospholipid syndrome are associated with infections, mainly ... this finding implies that a current infection with these agents, i.e. toxoplasma and rubella, might either be related to the pathogenesis of antiphospholipid syndrome or alternatively to its manifestations. [more...]

Prevalence of antiphospholipid antibodies among women experiencing unexplained infertility and recurrent implantation failure
Fertility and Sterility, 12/15/2009

Sauer R et al. – The prevalences of antiphospholipid antibodies (APAs) among 1,325 women with a history of unexplained infertility and 676 women experiencing [more...]

Current management of antiphospholipid syndrome-related thrombosis
Expert Review of Cardiovascular Therapy, 12/10/2009

Puente D et al. – Many physicians recommend a daily low dose of aspirin for primary thrombosis prevention in asymptomatic individuals with persistent antiphospholipid antibodies. However, recent data question the [more...]

Urgent Termination of Pregnancy in Pre-eclampsia and Panel of Antiphospholipid Antibodies
American Journal of Reproductive Immunology, 11/16/2009

Hradecky L et al. – Supposed increase in various antiphospholipid antibodies (aPLs) levels due to the stress during the short time of admission and a need for a quick medical decision to terminate the [more...]

Role of Tissue Factor in the Maternal Immunological Attack of the Embryo in the Antiphospholipid Syndrome
Clinical Reviews in Allergy and Immunology, 12/02/2009

Girardi G – The finding that TF is an important effector in aPL–induced inflammation may allow the development of new therapies to abrogate the inflammatory loop caused by tissue ... fetal medicine [more...]

Redox-reactive antiphospholipid antibody differences between serum from Alzheimer's patients and age-matched controls
Autoimmunity, 11/18/2009

Mcintyre JA et al. – In–sample Fisher's linear discriminate analysis found a sensitivity of 88% and a specificity of 94%. In–sample Classification and Regression [more...]

Thrombin Activatable Fibrinolysis Inhibitor and Clot Lysis Time in Pregnant Patients with Antiphospholipid Syndrome: Relationship with Pregnancy Outcome and Thrombosis
American Journal of Reproductive Immunology, 11/13/2009

Martinez–Zamora MA et al. – Patients with APS have impairment in fibrinolysis evidenced by prolonged CLT at baseline [more...]

Thrombin generation assay as a possible tool for assessment of reduced activity of clotting factors induced by antiphospholipid antibodies and in-vitro evaluation of treatment options
Blood Coagulation & Fibrinolysis, 11/03/2009

Livnat T et al. – The thrombin generation model showed that the addition of platelets and no recombinant [more...]

Predictors of the first cardiovascular event in patients with systemic lupus erythematosus - a prospective cohort study
Arthritis Research & Therapy, 12/14/2009

li>Follow up 99.5% after mean time of 8.3 years 24 patients (13%) had first CVE In age-adjusted Cox regression, any positive antiphospholipid antibody (aPL), elevated markers of endothelial activation (von Willebrand factor (vWf), soluble vascular cellular adhesion molecule-1 (sVCAM [more...]

Combination of heparin and aspirin is superior to aspirin alone in enhancing live births in patients with recurrent pregnancy loss and positive anti-phospholipid antibodies: A meta-analysis of randomized controlled trials and meta-regression
Rheumatology, 12/08/2009

li> Meta-regression using age at randomization, previous history of live births and episodes of miscarriages as covariates failed to predict RR of live birth [more...]