Avidity determines T-cell reactivity in abacavir hypersensitivity
European Journal of Immunology, 05/18/2012
Adam J et al. – The observed immediate activation and the non–involvement of the proteasome suggest that, in contrast to haptens, antiretroviral drug abacavir (abc)–specific T–cell stimulation does not require the formation of covalent bonds to produce a neo–antigenic determinant.



