Showing Latest Articles
Sufentanil preserves hemodynamics and left ventricular function in patients with ischemic heart disease Full Text
Acta Anaesthesiologica Scandinavica, 07/22/2011
Clinical Article
Bhavsar R et al.– Sufentanil preserves hemodynamic parameters as well as echocardiographic indices of left ventricular (LV) systolic and diastolic function in patients with ischemic heart disease (IHD).
Methods- Prospective observational study of thirty patients acting as their own control undergoing echocardiographic imaging before and after bolus Sufentanil 1.5–2.0 microgram/kg.
- Full invasive hemodynamic monitoring was established before Sufentanil administration.
- Global LV systolic function was evaluated with a global longitudinal peak systolic strain (GLPSS) by speckle tracking ultrasound; systolic displacement by tissue tracking (TT) and diastolic function was evaluated using Doppler tissue imaging and pulse wave Doppler.
- Hemodynamic monitoring showed a minor decline in systolic blood pressure from 159 to 154 mmHg (P=0.046).
- No changes were observed in the cardiac index, stroke volume index and heart rate.
- An unchanged TT score index (9.9 vs. 10.2 mm, P=0.428) and GLPSS (14.3 vs. 14.5%, P=0.658) indicated preserved LV global systolic function and unchanged E'/A' (0.95 vs. 0.89, P=0.110) and E/E' ratio (15.4 vs. 14.9, P=0.612) indicated unchanged diastolic function.