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Physical activity in middle-aged women and hip fracture risk: The UFO study
Osteoporosis International, 05/18/2010
Englund U et al. – In middle-aged women participating in the Umeå Fracture and Osteoporosis (UFO) study, we investigated whether physical activity is associated with a subsequent decreased risk of sustaining a hip fracture. An active lifestyle in middle age seems to reduce the risk of future hip fracture. Possible mechanisms may include improved muscle strength, coordination, and balance resulting in a decreased risk of falling and perhaps also direct skeletal benefits.
Methods- UFO study is a nested case-control study investigating associations between bone markers, lifestyle, and osteoporotic fractures
- Identified 81 female hip fracture cases that had reported lifestyle data before they sustained their fracture
- Each case was compared with two female controls who were identified from the same cohort and matched for age and week of reporting data, yielding a total cohort of 237 subjects
- Mean age at baseline was 57.2?±?5.0 years, and mean age at fracture was 65.4? ± ?6.4 years
- Conditional logistic regression analysis with adjustments for height, weight, smoking, and menopausal status showed that subjects who were regularly active with walking or had a moderate or high frequency of physical spare time activities (i.e. berry/mushroom picking and snow shovelling) were at reduced risk of sustaining a hip fracture (OR 0.14; 95% CI; 0.05–0.53 for walking and OR 0.19; 95% CI; 0.08–0.46, OR 0.17, 95% CI; 0.05–0.64 for moderate and high frequency of spare time activities, respectively) compared to more sedentary women
