Internal Medicine - Clinical Pharmacology News & Articles

1 Improving Long-Term ACS Management: Is There a Role for the New Antiplatelets Journal of Interventional Cardiology, May 22, 2012    Clinical Article

2 High Platelet Reactivity on Clopidogrel Therapy Correlates With Increased Coronary Atherosclerosis and Calcification JACC - Journal of the American College of Cardiology: Cardiovascular Imaging, May 22, 2012    Clinical Article

3 Systemic Exposure to Atorvastatin Between Asian and Caucasian Subjects: A Combined Analysis of 22 Studies American Journal of Therapeutics, May 22, 2012    Clinical Article

4 Visit-to-visit blood pressure variability in the European Lacidipine Study on Atherosclerosis: methodological aspects and effects of antihypertensive treatment Journal of Hypertension, May 22, 2012    Clinical Article

5 The effects of lowering LDL cholesterol with statin therapy in people at low risk of vascular disease: meta-analysis of individual data from 27 randomised trials The Lancet - Early Online Publication, May 21, 2012    Evidence Based Medicine    Clinical Article

6 Apixaban compared with warfarin in patients with atrial fibrillation and previous stroke or transient ischaemic attack: a subgroup analysis of the ARISTOTLE trial The Lancet Neurology, May 21, 2012    Clinical Article

7 Pharmacokinetics and pharmacodynamics of ticagrelor in patients with stable coronary artery disease: results from the onset-offset and respond studies Clinical Pharmacokinetics, May 21, 2012    Clinical Article

8 Use of carvedilol in hypertension: an update Vascular Health and Risk Management, May 21, 2012    Clinical Article

9 Evidence to support the use of vildagliptin monotherapy in the treatment of type 2 diabetes mellitus Full Text Vascular Health and Risk Management, May 21, 2012    Evidence Based Medicine    Clinical Article

10 Effect of azithromycin on systemic markers of inflammation in cystic fibrosis patients uninfected with Pseudomonas aeruginosa Chest, May 21, 2012    Clinical Article

11 Characteristics of persons who complied with and failed to comply with annual ivermectin treatment Tropical Medicine & International Health, May 21, 2012    Clinical Article

12 Phase 1 dose- escalation trial of clofarabine followed by escalating dose of fractionated cyclophosphamide in adults with relapsed or refractory acute leukaemias British Journal of Haematology, May 21, 2012

13 Simultaneous treatment of intractable pain and spasticity: observations of combined intrathecal baclofen-morphine therapy over a 10-year clinical experience European Journal of Physical and Rehabilitation Medicine, May 21, 2012    Clinical Article

14 Cisplatin and gemcitabine administered every two weeks in patients with locally advanced or metastatic urothelial carcinoma and impaired renal function European Journal of Cancer, May 21, 2012    Clinical Article

15 Comparison of the Therapeutic Efficacy of a Fixed Low-Dose Combination of Cinnarizine and Dimenhydrinate with Betahistine in Vestibular Neuritis: A Randomized, Double-Blind, Non-Inferiority Study Clinical Drug Investigation, May 21, 2012    Clinical Article

16 Meta-analysis: nonsteroidal anti-inflammatory drugs in biliary colic Alimentary Pharmacology and Therapeutics, May 21, 2012    Clinical Article

17 Pseudoprogression in Patients With Glioblastoma Multiforme After Concurrent Radiotherapy and Temozolomide American Journal of Clinical Oncology, May 21, 2012    Clinical Article

18 Methylchloroisothiazolinone/methylisothiazolinone contact sensitization: diverging trends in subgroups of IVDK patients in a period of 19 years Contact Dermatitis, May 21, 2012    Clinical Article

19 Lacosamide in Lennox-Gastaut Syndrome: Case Report Clinical Neuropharmacology, May 21, 2012

20 Electroclinical biomarkers of early peripheral neurotoxicity from oxaliplatin European Journal of Cancer Care, May 21, 2012    Clinical Article

1 Statin Use As a Moderator of Metformin Effect on Risk for Prostate Cancer Among Type 2 Diabetic Patients Diabetes Care, April 5, 2012

2 Statins as a possible cause of inflammatory and necrotizing myopathies Atherosclerosis, April 23, 2012

3 Which is the preferred angiotensin II receptor blocker-based combination therapy for blood pressure control in hypertensive patients with diabetic and non-diabetic renal impairment? Cardiovascular Diabetology, April 12, 2012    Free full text

4 On-treatment non–high-density lipoprotein cholesterol, apolipoprotein b, triglycerides, and lipid ratios in relation to residual vascular risk after treatment with potent statin therapy JACC - Journal of the American College of Cardiology, April 18, 2012

5 Renal safety of intensive cholesterol-lowering treatment with rosuvastatin: A retrospective analysis of renal adverse events among 40,600 participants in the rosuvastatin clinical development program Atherosclerosis, March 27, 2012

6 Statin use and the risk of Clostridium difficile in academic medical centres Gut, April 11, 2012

7 Comparison of lipid-modifying efficacy of rosuvastatin versus atorvastatin in patients with acute coronary syndrome (from the lunar study) The American Journal of Cardiology, April 17, 2012

8 Evidence-based Use of Statins for Primary Prevention of Cardiovascular Disease American Journal of Medicine, April 9, 2012    Evidence Based Medicine

9 The impact of statin therapy on long-term cardiovascular outcomes in an outpatient cardiology practice Archives of Medical Science, March 5, 2012

10 The Role of Antidepressants in the Management of Fibromyalgia Syndrome: A Systematic Review and Meta-Analysis CNS Drugs, April 3, 2012    Evidence Based Medicine

11 Effect of theophylline on exercise capacity in COPD patients treated with combination long-acting bronchodilator therapy: a pilot study International Journal of COPD, April 4, 2012    Free full text

12 A Double-Blind, Placebo-Controlled, Crossover Trial Comparing the Effects of Amiloride and Hydrochlorothiazide on Glucose Tolerance in Patients With Essential Hypertension Hypertension, April 10, 2012

13 New lipid-lowering drugs: an update International Journal of Clinical Practice, February 24, 2012

14 Lipid-lowering and anti-inflammatory effect of ezetimibe in hyperlipidemic patients with coronary artery disease Heart and Vessels, March 22, 2012

15 Elevation of fasting morning glucose relative to hemoglobin A1c in normoglycemic patients treated with niacin and with statins Journal of Clinical Lipidology, March 9, 2012

16 Improvement of arterial stiffness by reducing oxidative stress damage in elderly hypertensive patients after 6 months of atorvastatin therapy The Journal of Clinical Hypertension, April 25, 2012

17 A randomized controlled trial of allopurinol vs. placebo added on to antipsychotics in patients with schizophrenia or schizoaffective disorder Schizophrenia Research, April 11, 2012

18 Metformin and Hepatic Carcinogenesis Cancer Prevention Research, April 11, 2012

19 Further Assessment to Determine the Additive Effect of Botulinum Toxin Type A on an Upper Extremity Exercise Program to Enhance Function Among Individuals With Chronic Stroke but Extensor Capability Archives of Physical Medicine and Rehabilitation, April 11, 2012

20 Pharmacologic management of osteoarthritis-related pain in older adults: a review shows that many drug therapies provide small-to-modest pain relief Orthopaedic Nursing, April 11, 2012