Full Text Articles in Internal Medicine

1Benefit of early statin therapy in patients with acute myocardial infarction who have extremely low low-density lipoprotein cholesterolJACC - Journal of the American College of Cardiology, October 08, 2012  Full Text  Clinical Article
2Differential Effects of Adiposity on Pharmacodynamics of Basal Insulins NPH, Glargine, and Detemir in Type 2 DiabetesDiabetes Care, October 08, 2012  Full Text
3Phase I/II and Pharmacodynamic Study of Dovitinib (TKI258)-an Inhibitor of Fibroblast Growth Factor Receptors and VEGF Receptors-in Patients with Advanced MelanomaClinical Cancer Research, October 08, 2012  Full Text  Clinical Article
4Multicenter, Phase II Study of Axitinib, a Selective Second-Generation Inhibitor of Vascular Endothelial Growth Factor Receptors 1, 2, 3, in Patients with Metastatic MelanomaClinical Cancer Research, October 08, 2012  Full Text  Clinical Article
5A Phase 1 dose-escalation study of the safety and pharmacokinetics of once-daily oral foretinib, a multi-kinase inhibitor, in patients with solid tumorsInvestigational New Drugs, October 08, 2012  Full Text  Clinical Article
6A Phase I Dose Esclation Study of Tivantinib in Adult Pts w Metastatic Solid TumorsClinical Cancer Research, October 08, 2012  Full Text  Clinical Article
7Pam50 breast cancer subtyping by RT-QPCR and concordance with standard clinical molecular markersBMC Genomics, October 08, 2012  Full Text
8A prospective cohort study of health behavior profiles after age 50 and mortality riskBMC Public Health, October 08, 2012  Full Text
9Phase I and pharmacokinetic study of pazopanib and lapatinib combination therapy in patients with advanced solid tumorsInvestigational New Drugs, October 08, 2012  Full Text  Clinical Article
10The high prevalence of chronic kidney disease-mineral bone disorders: A hospital-based cross-sectional studyIndian Journal of Nephrology, October 08, 2012  Full Text  Clinical Article
1Cognitive problems are common after cardiac arrestLund University News, April 24, 2015
2Brainy Bones: New research reveals how our skeleton is a lot like our brainMonash University News, April 24, 2015
3Statins show promise as a prevention tool for adults 75 and older, OSU study showsOregon State University News, April 24, 2015
4Delayed diagnosis of coeliac disease may put lives at risk: Is screening the solution?United European Gastroenterology News, April 24, 2015
5New research shows how to tackle obesityThe University of Sheffield News, April 24, 2015
6Using human fat cells to fight infectionQueensland Brain Insitute News, April 24, 2015
7Nih-funded research leads to approval of drug for acute radiation injuryNational Institute of Allergy and Infectious Disease - News, April 24, 2015
8New test helps doctors tailor treatment for individual patientsThe University of Iowa Health News, April 24, 2015
9Solving real-world problems with unconventional solutions: Using bacteria to heal woundsTexas A&M University News, April 24, 2015
10New gel medication delays release of drug to benefit the patientThe University of Huddersfield News, April 24, 2015

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Muscle strength in adolescence decreases CVD risk

As reported in BMC Medicine, adolescents (n=38588) with the highest tertile of muscle strength had a decreased risk of CVD (HR=0.88) compared to adolescents with the lowest tertile of muscle strength after 42 y of follow-up. Of note, low muscle strength in adolescence by itself had no effect on CVD risk in middle age (HR=0.99). In contrast, high muscle strength in adolescence significantly decreased the risk of CVD in middle age (HR=1.31).

Relationship benefit in women with IHD

As reported in Clinical Infectious Diseases, HIV-infected patients are at increased risk for non-Hodgkin‘s lymphoma (NHL). Of 6036 patients with 21607 person-years of follow-up, there were 37 incident cases of NHL. Compared to patients with ≤ 50 copies/mL, patients with 51-500 and > 500 copies/mL had HRs of 1.66 and 2.39 for NHL, respectively.

Mean platelet volume predicts silent cerebral infarction

As reported in the Internal Medicine Journal, the mean platelet volume is increased in patients with a silent cerebral infarction than in those without (10.4 vs. 9.2 fL). The OR for silent cerebral infarction was 7.822 in patients in the highest mean platelet volume quartile compared to the lowest quartile.

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