Mean platelet volume predicts silent cerebral infarction
As reported in the Internal Medicine Journal, the mean platelet volume is increased in patients with a silent cerebral infarction than in those without (10.4 vs. 9.2 fL). The OR for silent cerebral infarction was 7.822 in patients in the highest mean platelet volume quartile compared to the lowest quartile.
Soluble TNF receptor II increased in MS patients
As reported in the Journal of Neuroimmunology, soluble tumor necrosis factor receptor II levels are increased in patients with untreated multiple sclerosis (n-161) compared to healthy controls (n=46), and the levels increased over a 2-year follow-up, but were not associated with the severity of disability.
Sleep duration linked to lung cancer risk
As reported in BMC Public Health, men (age range, 42-60 years) who slept < 7 h/night or > 8 h/night are at increased risk for lung cancer. Specifically, amongst current smokers, the HR for lung cancer in men who slept < 6.5 h/night or > 8 h/night was 2.23 and 2.09, respectively. It is thought that melatonin excretion and/or low-grade inflammation account for this observation.