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Internal Medicine News Articles

What makes MDLinx Internal Medicine different from all the other primary care literature reviews? Our team of medical editors read over 2,000 medical journals daily so you can stay current on the latest Internal Medicine news in less that 5 minutes a day! They sort, rank and summarize every article that will impact your daily practice. They even mark which articles are available in free full text, which are clinical or evidence-based, and which have MDLinx Exclusive Author Commentary from the people who actually performed the research.

Also on this page you’ll see bonus content from our physician editor, D. Scott Cunningham, MD, PhD, in the form of his top highlights you can’t miss, along with clinical pearls from The Smartest Internist, a quiz competition from the editors of MDLinx Internal Medicine in collaboration with the Cleveland Clinic Center for Continuing Education.

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Latest (384) Full Text Articles (9654) Focus on COPD
Ranked, sorted, and summarized by MDLinx editors from the latest literature

1 Benefit of early statin therapy in patients with acute myocardial infarction who have extremely low low-density lipoprotein cholesterol Full Text JACC - Journal of the American College of Cardiology, October 8, 2012 Original Publication Date: October 7, 2011    Clinical Article

2 Differential Effects of Adiposity on Pharmacodynamics of Basal Insulins NPH, Glargine, and Detemir in Type 2 Diabetes Full Text Diabetes Care, October 8, 2012 Original Publication Date: October 7, 2011

3 Phase I/II and Pharmacodynamic Study of Dovitinib (TKI258)-an Inhibitor of Fibroblast Growth Factor Receptors and VEGF Receptors-in Patients with Advanced Melanoma Full Text Clinical Cancer Research, October 8, 2012 Original Publication Date: October 7, 2011    Clinical Article

4 Multicenter, Phase II Study of Axitinib, a Selective Second-Generation Inhibitor of Vascular Endothelial Growth Factor Receptors 1, 2, 3, in Patients with Metastatic Melanoma Full Text Clinical Cancer Research, October 8, 2012 Original Publication Date: October 7, 2011    Clinical Article

5 A Phase 1 dose-escalation study of the safety and pharmacokinetics of once-daily oral foretinib, a multi-kinase inhibitor, in patients with solid tumors Full Text Investigational New Drugs, October 8, 2012    Clinical Article

6 A Phase I Dose Esclation Study of Tivantinib in Adult Pts w Metastatic Solid Tumors Full Text Clinical Cancer Research, October 8, 2012 Original Publication Date: October 7, 2011    Clinical Article

7 Pam50 breast cancer subtyping by RT-QPCR and concordance with standard clinical molecular markers Full Text BMC Genomics, October 8, 2012

8 A prospective cohort study of health behavior profiles after age 50 and mortality risk Full Text BMC Public Health, October 8, 2012

9 Phase I and pharmacokinetic study of pazopanib and lapatinib combination therapy in patients with advanced solid tumors Full Text Investigational New Drugs, October 8, 2012    Clinical Article

10 The high prevalence of chronic kidney disease-mineral bone disorders: A hospital-based cross-sectional study Full Text Indian Journal of Nephrology, October 8, 2012    Clinical Article

11 Costs of Illness Due to Cholera, Costs of Immunization and Cost-Effectiveness of an Oral Cholera Mass Vaccination Campaign in Zanzibar Full Text PLoS Neglected Tropical Diseases, October 8, 2012    Clinical Article

12 Investigating a cluster of vulvar cancer in young women: a cross-sectional study of genital human papillomavirus prevalence Full Text BMC Infectious Diseases, October 8, 2012

13 The I405V and Taq1B polymorphisms of the CETP gene differentially affect sub-clinical carotid atherosclerosis Full Text Lipids in Health and Disease, October 8, 2012

14 Expression of Shigella flexneri gluQ-rs gene is linked to dksA and controlled by a transcriptional terminator Full Text BMC Microbiology, October 8, 2012

15 Haemoglobinuria among children with severe malaria attending tertiary care in Ibadan, Nigeria Full Text Malaria Journal, October 8, 2012

16 Therapeutics for Dengue: Recommendations for Design and Conduct of Early-Phase Clinical Trials Full Text PLoS Neglected Tropical Diseases, October 8, 2012

17 Differential Infectivity by the Oral Route of Trypanosoma cruzi Lineages Derived from Y Strain Full Text PLoS Neglected Tropical Diseases, October 8, 2012

18 Predictors of mortality in connective tissue disease-associated pulmonary arterial hypertension: a cohort study Full Text Arthritis Research & Therapy, October 8, 2012

19 Functional relationship between high mobility group A1 (HMGA1) protein and insulin-like growth factor binding protein 3 (IGFBP-3) in human chondrocytes Full Text Arthritis Research & Therapy, October 8, 2012

20 Secretome analysis of chondroitin sulfate-treated chondrocytes reveals its anti-angiogenic, anti-inflammatory and anti-catabolic properties Full Text Arthritis Research & Therapy, October 8, 2012

483 available pages FirstPrevious 1 2 3 4 5 6 7 8 9 10 Next Last

Clinical Pearls in Internal Medicine

Highlights in Internal Medicine

Vitamin D deficiency is associated with increased mortality in ICU patients

Among 130 patients requiring mechanical ventilation, 107 were vitamin D-deficient (< 20 ng/ml). Of the patients who did not survive, the length of survival was shorter in the vitamin D-deficient patients (15.3 vs. 24.2 days, respectively).

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Coronary artery calcium increases cardiovascular risk in patients with T2DM and HTN

Researchers at Tel-Aviv University have conducted a study to determine the value of coronary artery calcium (CAC) measurements in cardiovascular risk stratification in patients with T2DM and HTN. The study involved 423 patients enrolled in the International Nifedipine Study: Intervention as Goal for Hypertension Therapy. The patients had baseline CT scans for CAC measurement at baseline and were shown to be free of disease. Follow-up CT scans were performed at 3 and 15 years. Cardiovascular events (CVEs) occurred in 41 of 423 patients at 3 years and 111 of 268 patients at 15 years of follow-up. CVEs occurred in 15% and 52% (CAC+) and 7% and 32% (CAC-) of patients with T2DM at 3 and 15 years of follow-up, respectively. Compared to patients without T2DM and no CAC, the HRs for a CVE were 6.6 and 3.9 in T2DM patients with and without CAC, respectively.

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CAC scores add predictability to Framingham

Researchers at Erasmus University Medical Center in Rotterdam have evaluated 12 measures (N-terminal fragment of prohormone B-type natriuretic peptide levels, von Willebrand factor antigen levels, fibrinogen levels, chronic kidney disease, leukocyte count, C-reactive protein levels, homocysteine levels, uric acid levels, coronary artery calcium [CAC] scores, carotid intima–media thickness, peripheral arterial disease, and pulse wave velocity), in addition to Framingham risk scores for predicting coronary heart disease. Only the CAC was shown to add significantly to the Framingham risk score in predicting coronary heart disease.

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Most Popular Internal Med Articles

Last month's top read Top Articles of 2013

1 Is ginger effective for the treatment of irritable bowel syndrome? A double blind randomized controlled pilot trial Complementary Therapies in Medicine, March 4, 2014

2 Tea consumption and leukemia risk: A meta-analysis Tumor Biology, February 12, 2014    Evidence Based Medicine

3 Animal protein intake is associated with higher-level functional capacity in elderly adults: The Ohasama study Journal of the American Geriatrics Society, March 5, 2014

4 Effect of high-dose simvastatin on brain atrophy and disability in secondary progressive multiple sclerosis (MS-STAT): a randomised, placebo-controlled, phase 2 trial The Lancet, March 19, 2014    Evidence Based Medicine

5 Glycated hemoglobin measurement and prediction of cardiovascular disease JAMA, March 26, 2014    Evidence Based Medicine

6 Association of {beta}-blocker therapy with risks of adverse cardiovascular events and deaths in patients with ischemic heart disease undergoing noncardiac surgery: A Danish nationwide cohort study JAMA Internal Medicine, March 11, 2014    Evidence Based Medicine

7 Age-adjusted D-dimer cutoff levels to rule out pulmonary embolism: The ADJUST-PE study JAMA, March 20, 2014    Evidence Based Medicine

8 Mortality from ruptured abdominal aortic aneurysms: clinical lessons from a comparison of outcomes in England and the USA The Lancet, March 17, 2014    Evidence Based Medicine

9 Obstructive sleep apnea and risk of cardiovascular events and all-cause mortality: A decade-long historical cohort study PLoS Medicine, February 7, 2014    Free full text    Evidence Based Medicine

10 Effect of radiotherapy after mastectomy and axillary surgery on 10-year recurrence and 20-year breast cancer mortality: meta-analysis of individual patient data for 8135 women in 22 randomised trials The Lancet, March 24, 2014    Evidence Based Medicine

11 Multitarget stool DNA testing for colorectal-cancer screening New England Journal of Medicine, March 21, 2014    Evidence Based Medicine

12 Effects of vitamin D supplements on bone mineral density: a systematic review and meta-analysis The Lancet, October 11, 2013    Evidence Based Medicine

13 Dietary carrot consumption and the risk of prostate cancer European Journal of Nutrition, February 17, 2014

14 Treatment of venous thromboembolism JAMA, February 19, 2014    Evidence Based Medicine

15 Serum levels of fetuin-A, osteoprotegerin and osteopontin in patients with coronary artery disease: Effects of Statin (HMGCoA-Reductase Inhibitor) Therapy Clinical Drug Investigation, March 3, 2014

16 Effects of music on complications during hemodialysis for chronic renal failure patients Hemodialysis International, March 27, 2014

17 Egg consumption and risk of GI neoplasms: dose–response meta-analysis and systematic review European Journal of Nutrition, February 6, 2014    Evidence Based Medicine    Review Article

18 Effect of omega-3 fatty acid supplementation on cancer incidence, non-vascular death, and total mortality: a meta-analysis of randomized controlled trials BMC Public Health, March 5, 2014    Free full text    Evidence Based Medicine

19 Screening for prostate cancer with the prostate-specific antigen test: A review of current evidence JAMA, March 20, 2014    Evidence Based Medicine

20 Effects of spironolactone on long-term mortality and morbidity in patients with heart failure and mild or no symptoms The American Journal of the Medical Sciences, March 25, 2014    Evidence Based Medicine

Indexed Journals in Internal Medicine: New England Journal of Medicine, The Lancet, Archives of Internal Medicinemore

Other Topics in Internal Medicine

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