Internal Medicine News & Articles

What makes MDLinx Internal Medicine different from all the other primary care literature reviews? Our team of medical editors read over 2,000 medical journals every day so you can stay current in less than 5 minutes! They sort, rank and summarize every article that will impact your daily practice. They even mark which articles are available in free full text, which are clinical or evidence-based, and which have MDLinx Exclusive Author Commentary from the people who actually performed the research.

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Articles

Latest (227) Full Text Articles (9654) Focus on GERD & PUD

Ranked, sorted, and summarized by MDLinx editors from the latest literature

Eczema/Psoriasis

1 Psoriasis Is Not Associated with Atherosclerosis and Incident Cardiovascular Events: The Rotterdam Study Journal of Investigative Dermatology, May 8, 2013 Clinical Article

2 Low-dose methotrexate - a therapeutical kick in TNF-alpha antagonist treatment for recalcitrant psoriasis vulgaris Dermatologic Therapy, May 8, 2013 Clinical Article

3 Biologic Therapies in the Treatment of Psoriasis: A Comprehensive Evidence-Based Basic Science and Clinical Review and a Practical Guide to Tuberculosis Monitoring Clinical Reviews in Allergy and Immunology, May 8, 2013 Clinical Article

4 High prevalence of psoriatic arthritis in patients with severe psoriasis with suboptimal performance of screening questionnaires Annals of Rheumatic Diseases, May 8, 2013 Clinical Article

5 The burden of carotid artery plaques is higher in patients with psoriatic arthritis compared with those with psoriasis alone Annals of Rheumatic Diseases, May 8, 2013 Clinical Article

6 Fingernail psoriasis reconsidered: A case-control study Journal of the American Academy of Dermatology, May 8, 2013 Clinical Article

7 Ustekinumab in nail psoriasis: an open-label, uncontrolled, nonrandomized study Journal of Dermatological Treatment , May 8, 2013 Clinical Article

8 Potential role of ixekizumab in the treatment of moderate-to-severe plaque psoriasis Full Text Clinical, Cosmetic and Investigational Dermatology, May 8, 2013 Clinical Article

9 The Genetics of Psoriasis and Psoriatic Arthritis Clinical Reviews in Allergy and Immunology, May 8, 2013 Review Article

10 Soluble Biomarkers Associated with Response to Treatment with Tumor Necrosis Factor Inhibitors in Psoriatic Arthritis The Journal of Rheumatology, May 8, 2013 Clinical Article

11 Inflammation, Atherosclerosis, and Psoriasis Clinical Reviews in Allergy and Immunology, May 8, 2013 Review Article Clinical Article

12 Application and Modifications of Minimal Disease Activity Measures for Patients with Psoriatic Arthritis Treated with Adalimumab: Subanalyses of ADEPT The Journal of Rheumatology, May 8, 2013 Clinical Article

13 Psychological differences between early and late onset psoriasis: A study of personality traits, anxiety and depression in psoriasis British Journal of Dermatology, May 8, 2013 Review Article

14 Dexamethasone iontophoresis for the treatment of nail psoriasis Australasian Journal of Dermatology, May 8, 2013 Clinical Article

15 Psoriasis and phenotype of patients with early inflammatory back pain Annals of Rheumatic Diseases, May 8, 2013 Review Article Clinical Article

16 Disease characteristics in patients with and without psoriatic arthritis treated with etanercept Journal of the European Academy of Dermatology and Venereology, May 8, 2013 Clinical Article

17 Relationship between parathyroid hormone and subclinical myocardial dysfunction in patients with severe psoriasis Journal of the European Academy of Dermatology and Venereology, May 8, 2013 Review Article

18 Adalimumab: long-term safety in 23458 patients from global clinical trials in rheumatoid arthritis, juvenile idiopathic arthritis, ankylosing spondylitis, psoriatic arthritis, psoriasis and Crohns disease Annals of Rheumatic Diseases, April 6, 2013 Clinical Article

19 Diet and nutrition in psoriasis: analysis of the National Health and Nutrition Examination Survey (NHANES) in the United States Journal of the European Academy of Dermatology and Venereology, April 6, 2013 Review Article Clinical Article

20 Psoriasis, psoriatic arthritis and increased risk of incident Crohns disease in US women Annals of Rheumatic Diseases, April 6, 2013 Clinical Article

21 New developments in the management of psoriasis and psoriatic arthritis: a focus on apremilast Full Text Drug Design, Development and Therapy, April 6, 2013 Clinical Article

22 Biological treatments for moderate-to-severe psoriasis: indirect comparison Journal of Clinical Pharmacy and Therapeutics, April 6, 2013 Clinical Article

23 Role of psoriasis as independent predictor of cardiovascular disease: A meta-regression analysis International Journal of Cardiology, April 6, 2013 Evidence Based Medicine

24 TNF- antagonists and nail psoriasis: an open, 24-week, prospective cohort study in adult patients with psoriasis Expert Opinion on Biological Therapy, April 6, 2013 Clinical Article

25 Psoriasis Area Severity Index (PASI) and the Dermatology Life Quality Index (DLQI): the correlation between disease severity and psychological burden in patients treated with biological therapies Journal of the European Academy of Dermatology and Venereology, March 6, 2013 Review Article

Clinical Pearls in Internal Medicine

Vitamin D deficiency is more common with non-Caucasian patients, and those with lower social support, no insurance, diabetes, lower activity levels, higher parathyroid hormone levels, and higher body mass indexes
Eating an early breakfast and dinner when taking PPIs can lower FSSG scores and improve GERD symptoms. (Factors leading to increased FSSG scores were female gender, inadequate sleep, lack of breakfast, antihypertensive agent non-users and dinner just before bedtime.)
No single method of contraception is contraindicated by age alone, but caution should be exercised with estrogen-containing preparations in obese women over 40

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Highlights in Internal Medicine

Vitamin D deficiency is associated with increased mortality in ICU patients

Among 130 patients requiring mechanical ventilation, 107 were vitamin D-deficient (< 20 ng/ml). Of the patients who did not survive, the length of survival was shorter in the vitamin D-deficient patients (15.3 vs. 24.2 days, respectively).

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Coronary artery calcium increases cardiovascular risk in patients with T2DM and HTN

Researchers at Tel-Aviv University have conducted a study to determine the value of coronary artery calcium (CAC) measurements in cardiovascular risk stratification in patients with T2DM and HTN. The study involved 423 patients enrolled in the International Nifedipine Study: Intervention as Goal for Hypertension Therapy. The patients had baseline CT scans for CAC measurement at baseline and were shown to be free of disease. Follow-up CT scans were performed at 3 and 15 years. Cardiovascular events (CVEs) occurred in 41 of 423 patients at 3 years and 111 of 268 patients at 15 years of follow-up. CVEs occurred in 15% and 52% (CAC+) and 7% and 32% (CAC-) of patients with T2DM at 3 and 15 years of follow-up, respectively. Compared to patients without T2DM and no CAC, the HRs for a CVE were 6.6 and 3.9 in T2DM patients with and without CAC, respectively.

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CAC scores add predictability to Framingham

Researchers at Erasmus University Medical Center in Rotterdam have evaluated 12 measures (N-terminal fragment of prohormone B-type natriuretic peptide levels, von Willebrand factor antigen levels, fibrinogen levels, chronic kidney disease, leukocyte count, C-reactive protein levels, homocysteine levels, uric acid levels, coronary artery calcium [CAC] scores, carotid intima–media thickness, peripheral arterial disease, and pulse wave velocity), in addition to Framingham risk scores for predicting coronary heart disease. Only the CAC was shown to add significantly to the Framingham risk score in predicting coronary heart disease.

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Most Popular Internal Medicine Articles

Last month's top read Top Articles of 2012

1 Walking Versus Running for Hypertension, Cholesterol, and Diabetes Mellitus Risk Reduction Arteriosclerosis, Thrombosis, and Vascular Biology, April 17, 2013

2 Primary Prevention of Cardiovascular Disease with a Mediterranean Diet New England Journal of Medicine, April 8, 2013 Free full text

3 Vitamin D Levels for Preventing Acute Coronary Syndrome and Mortality: Evidence of a Non-Linear Association Journal of Clinical Endocrinology and Metabolism, March 27, 2013
Exclusive Author Commentary

4 Advances in Stroke Prevention in Atrial Fibrillation: Enhanced Risk Stratification Combined With the Newer Oral Anticoagulants Clinical Cardiology, April 11, 2013 Free full text Review Article

5 Effect of longer term modest salt reduction on blood pressure: Cochrane systematic review and meta-analysis of randomised trials British Medical Journal, April 25, 2013 Evidence Based Medicine Review Article

6 The Risk of Taking Ascorbic Acid JAMA Internal Medicine, February 5, 2013

7 Coronary artery bypass graft surgery versus percutaneous coronary intervention in patients with three-vessel disease and left main coronary disease: 5-year follow-up of the randomised, clinical SYNTAX trial The Lancet, April 18, 2013

8 Canagliflozin Compared With Sitagliptin for Patients With Type 2 Diabetes Who Do Not Have Adequate Glycemic Control With Metformin Plus Sulfonylurea: A 52-week randomized trial Diabetes Care, April 9, 2013

9 Enalapril And Carvedilol for Preventing Chemotherapy-Induced Left Ventricular Systolic Dysfunction in Patients with Malignant Hemopathies. The OVERCOME Trial JACC - Journal of the American College of Cardiology, April 12, 2013

10 Drug Interactions with Grapefruit Juice British Journal of Medical Practitioners, February 12, 2013 Free full text

11 Outcomes of apixaban vs. warfarin by type and duration of atrial fibrillation: results from the ARISTOTLE trial European Heart Journal, April 22, 2013

12 Pulmonary hypertension: diagnosis and management British Medical Journal, April 23, 2013 Review Article

13 Infective Endocarditis New England Journal of Medicine, April 12, 2013

14 Effects of vitamin D supplementation on body fat accumulation, inflammation, and metabolic risk factors in obese adults with low vitamin D levels -- Results from a randomized trial European Journal of Internal Medicine , April 11, 2013

15 Vitamin D and Calcium Supplementation to Prevent Fractures in Adults: U.S. Preventive Services Task Force Recommendation Statement Annals of Internal Medicine, February 26, 2013 Clinical Guideline

16 Infective Endocarditis New England Journal of Medicine, April 24, 2013 Review Article

17 Osteoporosis treatment European Journal of Internal Medicine , April 24, 2013

18 Bone mineral density testing: Is a T score enough to determine the screening interval? Cleveland Clinic Journal of Medicine, April 3, 2013 Free full text

19 The impact of coffee on health Maturitas, February 26, 2013

20 Efficacy and safety of linagliptin in type 2 diabetes subjects at high risk for renal and cardiovascular disease: a pooled analysis of six phase III clinical trials Cardiovascular Diabetology, April 12, 2013 Free full text

Indexed Journals in Internal Medicine: New England Journal of Medicine, The Lancet, Archives of Internal Medicine more

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Internal Medicine News & Articles

Articles

Clinical Pearls in Internal Medicine

Highlights in Internal Medicine

Vitamin D deficiency is associated with increased mortality in ICU patients

Coronary artery calcium increases cardiovascular risk in patients with T2DM and HTN

CAC scores add predictability to Framingham

Most Popular Internal Medicine Articles

Other Topics in Internal Medicine