Internal Medicine News & Articles

What makes MDLinx Internal Medicine different from all the other primary care literature reviews? Our team of medical editors read over 2,000 medical journals every day so you can stay current in less than 5 minutes! They sort, rank and summarize every article that will impact your daily practice. They even mark which articles are available in free full text, which are clinical or evidence-based, and which have MDLinx Exclusive Author Commentary from the people who actually performed the research.

Also on this page you’ll see bonus content from our physician editor, D. Scott Cunningham, MD, PhD, in the form of his top highlights you can’t miss, along with clinical pearls from The Smartest Internist, a quiz competition from the editors of MDLinx Internal Medicine in collaboration with the Cleveland Clinic Center for Continuing Education.

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Articles

Latest (248) Full Text Articles (9654) Focus on Diabetes Mellitus

Ranked, sorted, and summarized by MDLinx editors from the latest literature

Anxiety Disorders

1 Meta-analysis: Aerobic exercise for the treatment of anxiety disorders Progress in Neuro-Psychopharmacology and Biological Psychiatry, June 8, 2013 Evidence Based Medicine Review Article

2 The effect of qigong on depressive and anxiety symptoms: a systematic review and meta-analysis of randomized controlled trials Full Text Evidence-based Complementary and Alternative Medicine , June 8, 2013 Evidence Based Medicine Review Article Clinical Article

3 The best next drug in the course of generalized anxiety disorders: the PN-GAD-algorithm International Journal of Psychiatry in Clinical Practice, June 8, 2013 Clinical Article

4 Cognitive behavioral therapy age effects in child and adolescent anxiety: an individual patient data metaanalysis Depression and Anxiety, June 8, 2013 Evidence Based Medicine Review Article

5 Anxiolytics in patients suffering a suspected acute coronary syndrome: Multi-centre randomised controlled trial in Emergency Medical Service International Journal of Cardiology, June 8, 2013 Clinical Article

6 The impact of first eye cataract surgery on mental health contacts for depression and/or anxiety: a population-based study using linked data Acta Ophthalmologica, June 8, 2013 Clinical Article

7 Anxiety-Promoting Parenting Behaviors: A Comparison of Anxious Parents with and without Social Anxiety Disorder Child Psychiatry and Human Development, June 8, 2013 Clinical Article

8 An Anxious Heart: Anxiety and the Onset of Cardiovascular Diseases Progress in Cardiovascular Diseases , May 23, 2013 Clinical Article

9 Effects of exercise training on quality of life, symptoms of depression, symptoms of anxiety and emotional well-being in type 2 diabetes mellitus: a systematic review Diabetologia - Clinical and Experimental Diabetes and Metabolism, May 23, 2013 Evidence Based Medicine Review Article

10 Predictors of Acute Postsurgical Pain and Anxiety Following Primary Total Hip and Knee Arthroplasty The Journal of Pain, May 23, 2013 Clinical Article

11 Excessive Mood Elevation and Behavioral Activation with Antidepressant Treatment of Juvenile Depressive and Anxiety Disorders: A Systematic Review Psychotherapy and Psychosomatics, May 23, 2013 Evidence Based Medicine Review Article

12 Prognostic Value of Depression, Anxiety, and Anger in Hospitalized Cardiovascular Disease Patients for Predicting Adverse Cardiac Outcomes The American Journal of Cardiology, May 23, 2013 Clinical Article

13 Bright light therapy for symptoms of anxiety and depression in focal epilepsy: randomised controlled trial The British Journal of Psychiatry, May 23, 2013 Clinical Article

14 Effects of Patient-Directed Music Intervention on Anxiety and Sedative Exposure in Critically Ill Patients Receiving Mechanical Ventilatory Support: A Randomized Clinical Trial JAMA, May 23, 2013 Evidence Based Medicine Clinical Article

15 A clinically useful social anxiety disorder outcome scale Comprehensive Psychiatry, May 23, 2013 Review Article

16 Prevalence of Pain-Predominant Functional Gastrointestinal Disorders and Somatic Symptoms in Patients with Anxiety or Depressive Disorders The Journal of Pediatrics, May 23, 2013 Clinical Article

17 Characteristics of Worry in Generalized Anxiety Disorder Journal of Behavior Therapy and Experimental Psychiatry, May 23, 2013 Clinical Article
Exclusive Author Commentary

18 The effectiveness of booster sessions in CBT treatment for child and adolescent mood and anxiety disorders Depression and Anxiety, May 23, 2013 Clinical Article

19 Childhood maltreatment and response to cognitive behavioral therapy among individuals with social anxiety disorder Depression and Anxiety, May 23, 2013 Clinical Article

20 Mindfulness and emotion regulation in depression and anxiety: common and distinct mechanisms of action Depression and Anxiety, May 23, 2013 Clinical Article

21 Smoking and social anxiety: The roles of gender and smoking motives Addictive Behaviours, May 23, 2013 Review Article

22 The comorbidity of anxiety and depressive symptoms in older adults with attention-deficit/hyperactivity disorder: A longitudinal study Journal of Affective Disorders, May 23, 2013 Clinical Article

23 Personality, physical activity, and symptoms of anxiety and depression: the HUNT study Social Psychiatry and Psychiatric Epidemiology, May 23, 2013 Clinical Article

24 Impact of Early Adolescent Anxiety Disorders on Self-Esteem Development From Adolescence to Young Adulthood Journal of Adolescent Health, May 23, 2013 Review Article

25 Pharmacologic Treatment of Anxiety Disorders in Parkinson Disease The American Journal of Geriatric Psychiatry, May 23, 2013 Clinical Article

26 Relationship between sleep disturbance and depression, anxiety, and functioning in college students Depression and Anxiety, May 23, 2013 Clinical Article

27 Efficacy of the novel antidepressant agomelatine for anxiety symptoms in major depression Human Psychopharmacology: Clinical and Experimental, April 13, 2013 Clinical Article

28 Effects of pregabalin on sleep in generalized anxiety disorder International Journal of Neuropsychopharmacology, April 13, 2013 Review Article Clinical Article

29 Frequent Insufficient Sleep and Anxiety and Depressive Disorders Among U.S. Community Dwellers in 20 States, 2010 Psychiatric Services, April 13, 2013 Clinical Article

30 Comorbid anxiety and neurocognitive dysfunctions in children with ADHD European Child and Adolescent Psychiatry, April 13, 2013 Clinical Article

31 The effect of anxiety on heart rate variability, depression, and sleep in Chronic Obstructive Pulmonary Disease Journal of Psychosomatic Research, April 13, 2013 Clinical Article

32 Anxiety and 10-year risk of incident and recurrent depressive symptomatology in older adults Depression and Anxiety, April 13, 2013 Clinical Article

Clinical Pearls in Internal Medicine

Vitamin D deficiency is more common with non-Caucasian patients, and those with lower social support, no insurance, diabetes, lower activity levels, higher parathyroid hormone levels, and higher body mass indexes
Eating an early breakfast and dinner when taking PPIs can lower FSSG scores and improve GERD symptoms. (Factors leading to increased FSSG scores were female gender, inadequate sleep, lack of breakfast, antihypertensive agent non-users and dinner just before bedtime.)
No single method of contraception is contraindicated by age alone, but caution should be exercised with estrogen-containing preparations in obese women over 40

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Highlights in Internal Medicine

Vitamin D deficiency is associated with increased mortality in ICU patients

Among 130 patients requiring mechanical ventilation, 107 were vitamin D-deficient (< 20 ng/ml). Of the patients who did not survive, the length of survival was shorter in the vitamin D-deficient patients (15.3 vs. 24.2 days, respectively).

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Coronary artery calcium increases cardiovascular risk in patients with T2DM and HTN

Researchers at Tel-Aviv University have conducted a study to determine the value of coronary artery calcium (CAC) measurements in cardiovascular risk stratification in patients with T2DM and HTN. The study involved 423 patients enrolled in the International Nifedipine Study: Intervention as Goal for Hypertension Therapy. The patients had baseline CT scans for CAC measurement at baseline and were shown to be free of disease. Follow-up CT scans were performed at 3 and 15 years. Cardiovascular events (CVEs) occurred in 41 of 423 patients at 3 years and 111 of 268 patients at 15 years of follow-up. CVEs occurred in 15% and 52% (CAC+) and 7% and 32% (CAC-) of patients with T2DM at 3 and 15 years of follow-up, respectively. Compared to patients without T2DM and no CAC, the HRs for a CVE were 6.6 and 3.9 in T2DM patients with and without CAC, respectively.

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CAC scores add predictability to Framingham

Researchers at Erasmus University Medical Center in Rotterdam have evaluated 12 measures (N-terminal fragment of prohormone B-type natriuretic peptide levels, von Willebrand factor antigen levels, fibrinogen levels, chronic kidney disease, leukocyte count, C-reactive protein levels, homocysteine levels, uric acid levels, coronary artery calcium [CAC] scores, carotid intima–media thickness, peripheral arterial disease, and pulse wave velocity), in addition to Framingham risk scores for predicting coronary heart disease. Only the CAC was shown to add significantly to the Framingham risk score in predicting coronary heart disease.

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Most Popular Internal Med Articles

Last month's top read Top Articles of 2012

1 Aspirin: Its risks, benefits, and optimal use in preventing cardiovascular events Cleveland Clinic Journal of Medicine, May 8, 2013 Free full text

2 Relationship between 25-Hydroxyvitamin D and All-cause and Cardiovascular Disease Mortality American Journal of Medicine, May 24, 2013 Review Article

3 The effect of topiramate on weight loss in patients with type 2 diabetes Journal of Research in Medical Sciences, May 14, 2013 Evidence Based Medicine

4 The Prevalence and Prognostic Role of Vitamin D Deficiency in Patients with Acute Coronary Syndrome Heart, Lung, and Circulation, April 30, 2013

5 Egg consumption and risk of cardiovascular diseases and diabetes: A meta-analysis Atherosclerosis, May 8, 2013 Evidence Based Medicine Review Article

6 Effect of longer term modest salt reduction on blood pressure: Cochrane systematic review and meta-analysis of randomised trials British Medical Journal, April 25, 2013 Evidence Based Medicine Review Article

7 An Update on the Cardiovascular Pleiotropic Effects of Milk and Milk Products The Journal of Clinical Hypertension, May 7, 2013 Review Article

8 Walking Versus Running for Hypertension, Cholesterol, and Diabetes Mellitus Risk Reduction Arteriosclerosis, Thrombosis, and Vascular Biology, April 17, 2013

9 Anger and the Heart: Perspectives on Cardiac Risk, Mechanisms and Interventions Progress in Cardiovascular Diseases , May 1, 2013

10 1:1 atrial-flutter. Prevalence and clinical characteristics International Journal of Cardiology, May 2, 2013

11 Vitamin D Levels for Preventing Acute Coronary Syndrome and Mortality: Evidence of a Non-Linear Association Journal of Clinical Endocrinology and Metabolism, March 27, 2013
Exclusive Author Commentary

12 New Oral Anticoagulants in Non-Valvular Atrial Fibrillation High Blood Pressure & Cardiovascular Prevention, May 13, 2013

13 Acute myocardial infarction leads to acceleration of atherosclerosis Atherosclerosis, May 1, 2013 Review Article

14 An Anxious Heart: Anxiety and the Onset of Cardiovascular Diseases Progress in Cardiovascular Diseases , May 1, 2013

15 Primary Prevention of Cardiovascular Disease with a Mediterranean Diet New England Journal of Medicine, April 8, 2013 Free full text

16 Cost-effectiveness of a coronary heart disease secondary prevention program in patients with myocardial infarction: results from a randomised controlled trial BMC Cardiovascular Disorders, May 7, 2013 Free full text

17 Teriparatide and denosumab, alone or combined, in women with postmenopausal osteoporosis: the DATA study randomised trial The Lancet, May 16, 2013

18 Risk of venous thromboembolism associated with peripherally inserted central catheters: a systematic review and meta-analysis The Lancet, May 20, 2013

19 The Effects of Ezetimibe/Simvastatin versus Simvastatin Monotherapy on Platelet and Inflammatory Biomarkers in Patients with Metabolic Syndrome Cardiology, May 9, 2013

20 Association Between a Hospital's Rate of Cardiac Arrest Incidence and Cardiac Arrest Survival JAMA Internal Medicine, May 21, 2013 Evidence Based Medicine

Indexed Journals in Internal Medicine: New England Journal of Medicine, The Lancet, Archives of Internal Medicine more

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Internal Medicine News & Articles

Articles

Clinical Pearls in Internal Medicine

Highlights in Internal Medicine

Vitamin D deficiency is associated with increased mortality in ICU patients

Coronary artery calcium increases cardiovascular risk in patients with T2DM and HTN

CAC scores add predictability to Framingham

Most Popular Internal Med Articles

Other Topics in Internal Medicine