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Internal Medicine News & Articles

What makes MDLinx Internal Medicine different from all the other primary care literature reviews? Our team of medical editors read over 2,000 medical journals every day so you can stay current in less than 5 minutes! They sort, rank and summarize every article that will impact your daily practice. They even mark which articles are available in free full text, which are clinical or evidence-based, and which have MDLinx Exclusive Author Commentary from the people who actually performed the research.

Also on this page you’ll see bonus content from our physician editor, D. Scott Cunningham, MD, PhD, in the form of his top highlights you can’t miss, along with clinical pearls from The Smartest Internist, a quiz competition from the editors of MDLinx Internal Medicine in collaboration with the Cleveland Clinic Center for Continuing Education.

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Articles

Latest (277) Full Text Articles (9654) Focus on Depression
Ranked, sorted, and summarized by MDLinx editors from the latest literature

1 Efficacy of vitamin C as an adjunct to fluoxetine therapy in pediatric major depressive disorder: a randomized, double-blind, placebo-controlled pilot study Full Text Nutrition Journal, May 21, 2013    Clinical Article

2 Parental depression, maternal antidepressant use during pregnancy, and risk of autism spectrum disorders: population based case-control study Full Text British Medical Journal, May 21, 2013    Clinical Article

3 Risperidone, quetiapine, and olanzapine adjunctive treatments in major depression with psychotic features: a comparative study Full Text Neuropsychiatric Disease and Treatment, May 21, 2013    Clinical Article

4 A randomised, controlled trial of a dietary intervention for adults with major depression (the SMILES trial): study protocol Full Text BMC Psychiatry, May 21, 2013    Clinical Article

5 The sertraline versus electrical current therapy for treating depression clinical study (SELECT-TDCS): results of the crossover and follow-up phases Depression and Anxiety, May 21, 2013    Clinical Article

6 Curcumin as an Add-On to Antidepressive Treatment: A Randomized, Double-Blind, Placebo-Controlled, Pilot Clinical Study Clinical Neuropharmacology, May 21, 2013    Clinical Article

7 Rapid Effects of Deep Brain Stimulation for Treatment-Resistant Major Depression Biological Psychiatry, May 21, 2013    Clinical Article

8 Efficacy of individualized homeopathic treatment and fluoxetine for moderate to severe depression in peri- and postmenopausal women (HOMDEP-MENOP): study protocol for a randomized, double-dummy, double-blind, placebo-controlled trial Full Text Trials, May 21, 2013    Clinical Article

9 Lower CSF Interleukin-6 predicts future depression in a population-based sample of older women followed for 17 years Brain, Behavior, and Immunity, May 21, 2013    Clinical Article
Exclusive Author Commentary

10 Evidence-Based Recommendations for the Prescription of Exercise for Major Depressive Disorder Journal of Psychiatric Practice, May 21, 2013    Evidence Based Medicine    Review Article    Clinical Article

11 A review of lifestyle factors that contribute to important pathways associated with major depression: Diet, sleep and exercise Journal of Affective Disorders, May 21, 2013    Review Article

12 The association between low vitamin D and depressive disorders Full Text Molecular Psychiatry, April 20, 2013    Clinical Article

13 Personalised intervention for people with depression and severe COPD The British Journal of Psychiatry, April 20, 2013    Clinical Article

14 Varicella Zoster Virus-Specific Immune Responses to a Herpes Zoster Vaccine in Elderly Recipients With Major Depression and the Impact of Antidepressant Medications Clinical Infectious Diseases, April 20, 2013    Clinical Article

15 A 6-week randomized controlled trial with 4-week follow-up of acupuncture combined with paroxetine in patients with major depressive disorder Journal of Psychiatric Research, April 20, 2013    Clinical Article

16 Depression and systemic lupus erythematosus: a systematic review Lupus, April 20, 2013    Evidence Based Medicine    Clinical Article

17 Therapeutic effects of vitamin D as adjunctive therapy to fluoxetine in patients with major depressive disorder Australian and New Zealand Journal of Psychiatry, March 30, 2013    Clinical Article

18 Antidepressants for depression in Parkinsons disease: systematic review and meta-analysis Journal of Psychopharmacology, March 30, 2013    Evidence Based Medicine    Review Article

19 The effect of sunlight exposure on interleukin-6 levels in depressive and non-depressive subjects Full Text BMC Psychiatry, March 30, 2013    Clinical Article

20 New pathways of increased cardiovascular risk in depression: A pilot study on the association of high-sensitivity C-reactive protein with pro-atherosclerotic markers in patients with depression Journal of Affective Disorders, March 30, 2013    Clinical Article

21 Quetiapine XR monotherapy in major depressive disorder: a pooled analysis to assess the influence of baseline severity on efficacy International Clinical Psychopharmacology, March 30, 2013    Clinical Article

22 Serum dehydroepiandrosterone (DHEA) and DHEA-sulfate (S) levels in medicated patients with major depressive disorder compared with controls Journal of Affective Disorders, March 30, 2013    Clinical Article

23 Attention-deficit/hyperactivity disorder in adolescence predicts onset of major depressive disorder through early adulthood Depression and Anxiety, March 30, 2013    Clinical Article

Clinical Pearls in Internal Medicine

Highlights in Internal Medicine

Vitamin D deficiency is associated with increased mortality in ICU patients

Among 130 patients requiring mechanical ventilation, 107 were vitamin D-deficient (< 20 ng/ml). Of the patients who did not survive, the length of survival was shorter in the vitamin D-deficient patients (15.3 vs. 24.2 days, respectively).

Read the article summary

Coronary artery calcium increases cardiovascular risk in patients with T2DM and HTN

Researchers at Tel-Aviv University have conducted a study to determine the value of coronary artery calcium (CAC) measurements in cardiovascular risk stratification in patients with T2DM and HTN. The study involved 423 patients enrolled in the International Nifedipine Study: Intervention as Goal for Hypertension Therapy. The patients had baseline CT scans for CAC measurement at baseline and were shown to be free of disease. Follow-up CT scans were performed at 3 and 15 years. Cardiovascular events (CVEs) occurred in 41 of 423 patients at 3 years and 111 of 268 patients at 15 years of follow-up. CVEs occurred in 15% and 52% (CAC+) and 7% and 32% (CAC-) of patients with T2DM at 3 and 15 years of follow-up, respectively. Compared to patients without T2DM and no CAC, the HRs for a CVE were 6.6 and 3.9 in T2DM patients with and without CAC, respectively.

Read the article summary

CAC scores add predictability to Framingham

Researchers at Erasmus University Medical Center in Rotterdam have evaluated 12 measures (N-terminal fragment of prohormone B-type natriuretic peptide levels, von Willebrand factor antigen levels, fibrinogen levels, chronic kidney disease, leukocyte count, C-reactive protein levels, homocysteine levels, uric acid levels, coronary artery calcium [CAC] scores, carotid intima–media thickness, peripheral arterial disease, and pulse wave velocity), in addition to Framingham risk scores for predicting coronary heart disease. Only the CAC was shown to add significantly to the Framingham risk score in predicting coronary heart disease.

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Most Popular Internal Medicine Articles

Last month's top read Top Articles of 2012

1 Walking Versus Running for Hypertension, Cholesterol, and Diabetes Mellitus Risk Reduction Arteriosclerosis, Thrombosis, and Vascular Biology, April 17, 2013

2 Primary Prevention of Cardiovascular Disease with a Mediterranean Diet New England Journal of Medicine, April 8, 2013    Free full text

3 Vitamin D Levels for Preventing Acute Coronary Syndrome and Mortality: Evidence of a Non-Linear Association Journal of Clinical Endocrinology and Metabolism, March 27, 2013
Exclusive Author Commentary

4 Advances in Stroke Prevention in Atrial Fibrillation: Enhanced Risk Stratification Combined With the Newer Oral Anticoagulants Clinical Cardiology, April 11, 2013    Free full text    Review Article

5 Effect of longer term modest salt reduction on blood pressure: Cochrane systematic review and meta-analysis of randomised trials British Medical Journal, April 25, 2013    Evidence Based Medicine    Review Article

6 The Risk of Taking Ascorbic Acid JAMA Internal Medicine, February 5, 2013

7 Coronary artery bypass graft surgery versus percutaneous coronary intervention in patients with three-vessel disease and left main coronary disease: 5-year follow-up of the randomised, clinical SYNTAX trial The Lancet, April 18, 2013

8 Canagliflozin Compared With Sitagliptin for Patients With Type 2 Diabetes Who Do Not Have Adequate Glycemic Control With Metformin Plus Sulfonylurea: A 52-week randomized trial Diabetes Care, April 9, 2013

9 Enalapril And Carvedilol for Preventing Chemotherapy-Induced Left Ventricular Systolic Dysfunction in Patients with Malignant Hemopathies. The OVERCOME Trial JACC - Journal of the American College of Cardiology, April 12, 2013

10 Drug Interactions with Grapefruit Juice British Journal of Medical Practitioners, February 12, 2013    Free full text

11 Outcomes of apixaban vs. warfarin by type and duration of atrial fibrillation: results from the ARISTOTLE trial European Heart Journal, April 22, 2013

12 Pulmonary hypertension: diagnosis and management British Medical Journal, April 23, 2013    Review Article

13 Infective Endocarditis New England Journal of Medicine, April 12, 2013

14 Effects of vitamin D supplementation on body fat accumulation, inflammation, and metabolic risk factors in obese adults with low vitamin D levels -- Results from a randomized trial European Journal of Internal Medicine , April 11, 2013

15 Vitamin D and Calcium Supplementation to Prevent Fractures in Adults: U.S. Preventive Services Task Force Recommendation Statement Annals of Internal Medicine, February 26, 2013    Clinical Guideline

16 Infective Endocarditis New England Journal of Medicine, April 24, 2013    Review Article

17 Osteoporosis treatment European Journal of Internal Medicine , April 24, 2013

18 Bone mineral density testing: Is a T score enough to determine the screening interval? Cleveland Clinic Journal of Medicine, April 3, 2013    Free full text

19 The impact of coffee on health Maturitas, February 26, 2013

20 Efficacy and safety of linagliptin in type 2 diabetes subjects at high risk for renal and cardiovascular disease: a pooled analysis of six phase III clinical trials Cardiovascular Diabetology, April 12, 2013    Free full text

Indexed Journals in Internal Medicine: New England Journal of Medicine, The Lancet, Archives of Internal Medicinemore

Other Topics in Internal Medicine

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