What makes MDLinx Internal Medicine different from all the other primary care literature reviews? Our team of medical editors read over 2,000 medical journals every day so you can stay current in less than 5 minutes! They sort, rank and summarize every article that will impact your daily practice. They even mark which articles are available in free full text, which are clinical or evidence-based, and which have MDLinx Exclusive Author Commentary from the people who actually performed the research.
Also on this page you’ll see bonus content from our physician editor, D. Scott Cunningham, MD, PhD, in the form of his top highlights you can’t miss, along with clinical pearls from The Smartest Internist, a quiz competition from the editors of MDLinx Internal Medicine in collaboration with the Cleveland Clinic Center for Continuing Education.
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901 Pharmaceutical treatment patterns for patients with a diagnosis related to chronic pain initiating a slow-release strong opioid treatment in Sweden Pain, September 20, 2012 Clinical Article
902 Associations between daily chronic pain intensity, daily anger expression, and trait anger expressiveness: An ecological momentary assessment study Pain, September 20, 2012
903 Influence of Directional Preference on Two Clinical Dichotomies: Acute Versus Chronic Pain and Axial Low Back Pain Versus Sciatica PM&R, September 20, 2012 Clinical Article
904 Effect of electroacupuncture on opioid consumption in patients with chronic musculoskeletal pain: protocol of a randomised controlled trial Full Text Trials, September 19, 2012 Clinical Article
905 Current challenges in translational pain research Trends in Pharmacological Sciences, September 18, 2012
906 Impact of sex hormonal changes on tension-type headache and migraine: a cross-sectional population-based survey in 2,600 women The Journal of Headache and Pain, September 17, 2012 Clinical Article
907 Characteristics of referred muscle pain to the head from active trigger points in women with myofascial temporomandibular pain and fibromyalgia syndrome The Journal of Headache and Pain, September 17, 2012
908 Control of Arthritis Pain with Anti-Nerve-Growth Factor: Risk and Benefit Current Rheumatology Reports, September 14, 2012 Clinical Article
909 Enoxaparin Treatment for Vulvodynia: A Randomized Controlled Trial. Obstetrics and Gynecology, September 14, 2012 Clinical Article
910 Stress is dominant in patients with depression and chronic low back pain. A qualitative study of psychotherapeutic interventions for patients with non-specific low back pain of 3--12 months' duration Full Text BMC Musculoskeletal Disorders, September 14, 2012 Clinical Article
911 Socio-demographic variation in chest pain incidence and subsequent coronary heart disease in primary care in the United Kingdom European Journal of Preventive Cardiology, September 14, 2012 Clinical Article
912 Chronic pain as a manifestation of potassium channel-complex autoimmunity Neurology, September 14, 2012
913 High prevalence of confirmed, but also of potential and believed, neuropathic pain in pain clinics European Journal of Pain, September 13, 2012 Clinical Article
914 Care for Patients with Chronic Nonmalignant Pain with and without Chronic Opioid Prescriptions: A Report from the Cincinnati Area Research Group (CARinG) Network Full Text Journal of the American Board of Family Medicine, September 13, 2012 Clinical Article
915 Significant others responses to pain in veterans with chronic pain and clinical levels of post-traumatic stress disorder symptomatology European Journal of Pain, September 13, 2012
916 Comparative study of efficacy and tolerability of flupirtine versus tramadol in non-steroidal anti-inflammatory drug intolerant mechanical low back pain Indian Journal of Rheumatology , September 12, 2012 Clinical Article
917 Central poststroke pain: somatosensory abnormalities and the presence of associated myofascial pain syndrome Full Text BMC Neurology, September 12, 2012 Clinical Article
918 Malignant Peripheral Nerve Sheath Tumor: The Utility of Fascicular Biopsy and Teased Fiber Studies Journal of Clinical Neuromuscular Disease, September 12, 2012
919 A novel CACNA1A mutation results in episodic ataxia with migrainous features without headache Cephalalgia, September 12, 2012
920 Randomized, Double-Blind, Placebo-Controlled Study to Assess the Efficacy and Toxicity of Subcutaneous Ketamine in the Management of Cancer Pain Journal of Clinical Oncology, September 11, 2012 Clinical Article
Among 130 patients requiring mechanical ventilation, 107 were vitamin D-deficient (< 20 ng/ml). Of the patients who did not survive, the length of survival was shorter in the vitamin D-deficient patients (15.3 vs. 24.2 days, respectively).
Read the article summaryResearchers at Tel-Aviv University have conducted a study to determine the value of coronary artery calcium (CAC) measurements in cardiovascular risk stratification in patients with T2DM and HTN. The study involved 423 patients enrolled in the International Nifedipine Study: Intervention as Goal for Hypertension Therapy. The patients had baseline CT scans for CAC measurement at baseline and were shown to be free of disease. Follow-up CT scans were performed at 3 and 15 years. Cardiovascular events (CVEs) occurred in 41 of 423 patients at 3 years and 111 of 268 patients at 15 years of follow-up. CVEs occurred in 15% and 52% (CAC+) and 7% and 32% (CAC-) of patients with T2DM at 3 and 15 years of follow-up, respectively. Compared to patients without T2DM and no CAC, the HRs for a CVE were 6.6 and 3.9 in T2DM patients with and without CAC, respectively.
Read the article summaryResearchers at Erasmus University Medical Center in Rotterdam have evaluated 12 measures (N-terminal fragment of prohormone B-type natriuretic peptide levels, von Willebrand factor antigen levels, fibrinogen levels, chronic kidney disease, leukocyte count, C-reactive protein levels, homocysteine levels, uric acid levels, coronary artery calcium [CAC] scores, carotid intima–media thickness, peripheral arterial disease, and pulse wave velocity), in addition to Framingham risk scores for predicting coronary heart disease. Only the CAC was shown to add significantly to the Framingham risk score in predicting coronary heart disease.
Read the article summary1 Diagnostic accuracy of nitroglycerine as a 'test of treatment' for cardiac chest pain: a systematic review Emergency Medicine Journal, May 9, 2011 Evidence Based Medicine
2 Kinase inhibitors: a new class of antirheumatic drugs Drug Design, Development and Therapy, September 24, 2012 Free full text
3 Activity of the neuroendocrine axes in patients with polymyalgia rheumatica before and after TNF-alpha blocking etanercept treatment Arthritis Research & Therapy, August 16, 2012 Free full text
4 The cytochrome P450 inhibitor, ketoconazole, inhibits oxidized linoleic acid metabolite-mediated peripheral inflammatory pain Molecular Pain, October 8, 2012 Free full text
Indexed Journals in Internal Medicine: New England Journal of Medicine, The Lancet, Archives of Internal Medicine more
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