What makes MDLinx Internal Medicine different from all the other primary care literature reviews? Our team of medical editors read over 2,000 medical journals every day so you can stay current in less than 5 minutes! They sort, rank and summarize every article that will impact your daily practice. They even mark which articles are available in free full text, which are clinical or evidence-based, and which have MDLinx Exclusive Author Commentary from the people who actually performed the research.
Also on this page you’ll see bonus content from our physician editor, D. Scott Cunningham, MD, PhD, in the form of his top highlights you can’t miss, along with clinical pearls from The Smartest Internist, a quiz competition from the editors of MDLinx Internal Medicine in collaboration with the Cleveland Clinic Center for Continuing Education.
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421 Knowledge and attitudes regarding pain management among Jordanian nursing students Nurse Education Today, February 27, 2013 Clinical Article
422 Effect of Supplementation With Hydrogen-rich Water in Patients With Interstitial Cystitis/Painful Bladder Syndrome Urology, February 27, 2013 Clinical Article
423 Pain referral patterns of the C1-C3 nerves: Implications for headache disorders Annals of Neurology , February 27, 2013 Review Article
424 The up-regulation of IL-6 in DRG and spinal dorsal horn contributes to neuropathic pain following L5 ventral root transection Experimental Neurology, February 26, 2013 Review Article
425 Are Facet Joint Bone Marrow Lesions and Other Facet Joint Features Associated With Low Back Pain? A Pilot Study PM&R, February 26, 2013 Clinical Article
426 An explanation of how migraine headaches can trigger relapse in systemic lupus erythematosus Medical Hypotheses, February 26, 2013 Clinical Article
427 Morphological macrovascular alterations in complex regional pain syndrome type I demonstrated by increased intima-media thickness Full Text BMC Neurology, February 26, 2013 Review Article
428 Cost-Effectiveness of Pharmaceutical Management for Osteoarthritis Pain: A Systematic Review of the Literature and Recommendations for Future Economic Evaluation Drugs & Aging, February 25, 2013 Evidence Based Medicine
429 Non-cardiac chest pain: time to extend the rapid access chest pain clinic? International Journal of Clinical Practice, February 25, 2013 Clinical Article
430 Epigenetic transcriptional activation of monocyte chemotactic protein 3 contributes to long-lasting neuropathic pain Brain, February 25, 2013 Review Article
431
Biopsychosocial care and the physiotherapy encounter: physiotherapists accounts of back pain consultations Full Text
BMC Musculoskeletal Disorders, February 25, 2013
Clinical Article
Exclusive Author Commentary
432 Trajectories of health care service utilization and differences in patient characteristics among adults with specific chronic pain: analysis of health plan member claims Full Text Journal of Pain Research, February 25, 2013
433 Diagnostic Utility of Routine EEG Study in Identifying Seizure as the Etiology of the Index Event in Patients Referred With a Diagnosis of Migraine and Not Otherwise Specified Headache Disorders Clinical EEG and Neuroscience, February 25, 2013 Review Article
434 Sympathetic nervous system responses to acupuncture and non-penetrating sham acupuncture in experimental forearm pain: a single-blind randomised descriptive study Acupuncture in Medicine, February 22, 2013 Clinical Article
435 Chronic Opioid Use in Fibromyalgia Syndrome: A Clinical Review JCR: Journal of Clinical Rheumatology, February 22, 2013 Review Article Clinical Article
436 Low back pain among textile workers: a cross-sectional study Occupational Medicine, February 22, 2013 Clinical Article
437 Work related neck pain in Iranian dentists: An epidemiological study Journal of Back and Musculoskeletal Rehabilitation, February 22, 2013 Evidence Based Medicine
438 Pain and inflammation in women with early-stage breast cancer prior to induction of chemotherapy Biological Research For Nursing, February 22, 2013 Clinical Article
439 Hypersomnia in children affected by migraine without aura: a questionnaire-based case-control study Full Text Neuropsychiatric Disease and Treatment, February 22, 2013 Clinical Article
440 Overview of Clostridium difficile Infection as an Emerging Health Care Facility-Acquired Infection Hospital Pharmacy, February 22, 2013 Review Article
Among 130 patients requiring mechanical ventilation, 107 were vitamin D-deficient (< 20 ng/ml). Of the patients who did not survive, the length of survival was shorter in the vitamin D-deficient patients (15.3 vs. 24.2 days, respectively).
Read the article summaryResearchers at Tel-Aviv University have conducted a study to determine the value of coronary artery calcium (CAC) measurements in cardiovascular risk stratification in patients with T2DM and HTN. The study involved 423 patients enrolled in the International Nifedipine Study: Intervention as Goal for Hypertension Therapy. The patients had baseline CT scans for CAC measurement at baseline and were shown to be free of disease. Follow-up CT scans were performed at 3 and 15 years. Cardiovascular events (CVEs) occurred in 41 of 423 patients at 3 years and 111 of 268 patients at 15 years of follow-up. CVEs occurred in 15% and 52% (CAC+) and 7% and 32% (CAC-) of patients with T2DM at 3 and 15 years of follow-up, respectively. Compared to patients without T2DM and no CAC, the HRs for a CVE were 6.6 and 3.9 in T2DM patients with and without CAC, respectively.
Read the article summaryResearchers at Erasmus University Medical Center in Rotterdam have evaluated 12 measures (N-terminal fragment of prohormone B-type natriuretic peptide levels, von Willebrand factor antigen levels, fibrinogen levels, chronic kidney disease, leukocyte count, C-reactive protein levels, homocysteine levels, uric acid levels, coronary artery calcium [CAC] scores, carotid intima–media thickness, peripheral arterial disease, and pulse wave velocity), in addition to Framingham risk scores for predicting coronary heart disease. Only the CAC was shown to add significantly to the Framingham risk score in predicting coronary heart disease.
Read the article summary1 The prevalence of widespread central hypersensitivity in chronic pain patients European Journal of Pain, May 24, 2013
2 Enhanced sensitivity to punctate painful stimuli in female patients with chronic low back pain BMC Neurology, September 25, 2012 Free full text
3 Practice Patterns and Perceptions About Parenteral Hydration in the Last Weeks of Life: A Survey of Palliative Care Physicians in Latin America Journal of Pain and Symptom Management, August 12, 2011
4 Migraine: possible role of shear-induced platelet aggregation with serotonin release Headache: The Journal of Head and Face Pain, May 11, 2012
5 Comparison of work-related fear-avoidance beliefs across different anatomical locations with musculoskeletal pain Journal of Pain Research, September 2, 2011 Free full text
Indexed Journals in Internal Medicine: New England Journal of Medicine, The Lancet, Archives of Internal Medicine more
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