What makes MDLinx Internal Medicine different from all the other primary care literature reviews? Our team of medical editors read over 2,000 medical journals every day so you can stay current in less than 5 minutes! They sort, rank and summarize every article that will impact your daily practice. They even mark which articles are available in free full text, which are clinical or evidence-based, and which have MDLinx Exclusive Author Commentary from the people who actually performed the research.
Also on this page you’ll see bonus content from our physician editor, D. Scott Cunningham, MD, PhD, in the form of his top highlights you can’t miss, along with clinical pearls from The Smartest Internist, a quiz competition from the editors of MDLinx Internal Medicine in collaboration with the Cleveland Clinic Center for Continuing Education.
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21 Semiological evaluation of pain according to its origin: a prospective, observational, and national study of current French medical practice Current Medical Research and Opinion, May 22, 2013 Clinical Article
22 Budget impact analysis of tapentadol extended release for the treatment of moderate to severe chronic noncancer pain Clinical Therapeutics, May 22, 2013 Review Article
23 Predicting return to work following treatment of chronic pain disorder Occupational Medicine, May 22, 2013 Review Article
24 Yield of Routine Provocative Cardiac Testing Among Patients in an Emergency Department–Based Chest Pain Unit: Yield of Stress Testing in Emergency Department Observation Units JAMA Internal Medicine, May 21, 2013 Evidence Based Medicine Clinical Article
25 Defensive Medicine—Legally Necessary but Ethically Wrong? Inpatient Stress Testing for Chest Pain in Low-Risk Patients JAMA Internal Medicine, May 21, 2013 Review Article
26 Increased Risk for Complications After Colorectal Surgery With Selective Cyclo-oxygenase 2 Inhibitor Etoricoxib Diseases of the Colon and Rectum, May 21, 2013 Clinical Article
27 Associations of Body Mass Index and Body Height With Low Back Pain in 829,791 Adolescents American Journal of Epidemiology, May 21, 2013 Review Article
28 Male chronic pelvic pain syndrome and the role of interdisciplinary pain management World Journal of Urology, May 21, 2013
29 Orchialgia and the chronic pelvic pain syndrome World Journal of Urology, May 21, 2013 Review Article
30 Steroid injection for inferior heel pain: a randomised controlled trial Annals of Rheumatic Diseases, May 21, 2013 Clinical Article
31 Risk factors and successful interventions for cricket-related low back pain: a systematic review British Journal of Sports Medicine, May 21, 2013 Evidence Based Medicine Clinical Article
32 Forced swim-induced musculoskeletal hyperalgesia is mediated by CRF2 receptors but not by TRPV1 receptors Neuropharmacology, May 21, 2013 Review Article
33 A Pilot Functional MRI Study of the Effects of Prefrontal rTMS on Pain Perception Pain Medicine, May 20, 2013 Clinical Article
34 Survey of European patients assessing their own noncancer chronic pain: results from Spain Current Medical Research and Opinion, May 20, 2013 Review Article
35 Self-reported headache among the employees of a Swiss university hospital: prevalence, disability, current treatment, and economic impact Full Text The Journal of Headache and Pain, May 20, 2013 Clinical Article
36 Effectiveness of Tai Chi Practice for Non-Specific Chronic Low Back Pain on Retired Athletes: A Randomized Controlled Study Journal of Musculoskeletal Pain , May 20, 2013 Clinical Article
37 Association Between Overweight and Low Back Pain: A Population-based Prospective Cohort Study of Adolescents Spine, May 20, 2013 Evidence Based Medicine Clinical Article
38 Time since diagnosis, treatment pathways and current pain status: a retrospective assessment in a back pain population Journal of Medical Economics , May 20, 2013 Clinical Article
39 Cost-Effectiveness of Duloxetine in Chronic Low Back Pain: A Quebec Societal Perspective Spine, May 17, 2013 Evidence Based Medicine Clinical Article
40 Prescription Opioids for Back Pain and Use of Medications for Erectile Dysfunction Spine, May 17, 2013 Evidence Based Medicine Clinical Article
Among 130 patients requiring mechanical ventilation, 107 were vitamin D-deficient (< 20 ng/ml). Of the patients who did not survive, the length of survival was shorter in the vitamin D-deficient patients (15.3 vs. 24.2 days, respectively).
Read the article summaryResearchers at Tel-Aviv University have conducted a study to determine the value of coronary artery calcium (CAC) measurements in cardiovascular risk stratification in patients with T2DM and HTN. The study involved 423 patients enrolled in the International Nifedipine Study: Intervention as Goal for Hypertension Therapy. The patients had baseline CT scans for CAC measurement at baseline and were shown to be free of disease. Follow-up CT scans were performed at 3 and 15 years. Cardiovascular events (CVEs) occurred in 41 of 423 patients at 3 years and 111 of 268 patients at 15 years of follow-up. CVEs occurred in 15% and 52% (CAC+) and 7% and 32% (CAC-) of patients with T2DM at 3 and 15 years of follow-up, respectively. Compared to patients without T2DM and no CAC, the HRs for a CVE were 6.6 and 3.9 in T2DM patients with and without CAC, respectively.
Read the article summaryResearchers at Erasmus University Medical Center in Rotterdam have evaluated 12 measures (N-terminal fragment of prohormone B-type natriuretic peptide levels, von Willebrand factor antigen levels, fibrinogen levels, chronic kidney disease, leukocyte count, C-reactive protein levels, homocysteine levels, uric acid levels, coronary artery calcium [CAC] scores, carotid intima–media thickness, peripheral arterial disease, and pulse wave velocity), in addition to Framingham risk scores for predicting coronary heart disease. Only the CAC was shown to add significantly to the Framingham risk score in predicting coronary heart disease.
Read the article summary1 Diagnostic accuracy of nitroglycerine as a 'test of treatment' for cardiac chest pain: a systematic review Emergency Medicine Journal, May 9, 2011 Evidence Based Medicine
2 Kinase inhibitors: a new class of antirheumatic drugs Drug Design, Development and Therapy, September 24, 2012 Free full text
3 Activity of the neuroendocrine axes in patients with polymyalgia rheumatica before and after TNF-alpha blocking etanercept treatment Arthritis Research & Therapy, August 16, 2012 Free full text
4 The cytochrome P450 inhibitor, ketoconazole, inhibits oxidized linoleic acid metabolite-mediated peripheral inflammatory pain Molecular Pain, October 8, 2012 Free full text
Indexed Journals in Internal Medicine: New England Journal of Medicine, The Lancet, Archives of Internal Medicine more
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