Internal Medicine - Allergy/Immunology News & Articles

What makes MDLinx Internal Medicine different from all the other primary care literature reviews? Our team of medical editors read over 2,000 medical journals every day so you can stay current in less than 5 minutes! They sort, rank and summarize every article that will impact your daily practice. They even mark which articles are available in free full text, which are clinical or evidence-based, and which have MDLinx Exclusive Author Commentary from the people who actually performed the research.

Also on this page you’ll see bonus content from our physician editor, D. Scott Cunningham, MD, PhD, in the form of his top highlights you can’t miss, along with clinical pearls from The Smartest Internist, a quiz competition from the editors of MDLinx Internal Medicine in collaboration with the Cleveland Clinic Center for Continuing Education.

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Articles

Latest (13) Full Text Articles (251) Focus on Angina

Ranked, sorted, and summarized by MDLinx editors from the latest literature

Topics:

1 In vitro drug causality assessment in Stevens-Johnson syndrome - alternatives for lymphocyte transformation test Clinical & Experimental Allergy, May 17, 2013 Clinical Article

2 Potential role of human-specific genes, human-specific microRNAs and human-specific non-coding regulatory RNAs in the pathogenesis of Systemic Sclerosis and Sjogren’s Syndrome Autoimmunity Reviews, May 17, 2013 Clinical Article

3 Lung Involvement in Connective Tissue Diseases: A Comprehensive Review and A Focus On Rheumatoid Arthritis Autoimmunity Reviews, May 17, 2013 Clinical Article

4 Non-Cigarette Tobacco and the Lung Clinical Reviews in Allergy and Immunology, May 17, 2013 Review Article

5 Current Status of Implementation of Self-Administration Training in Various Regions of Europe, Canada and the USA in the Management of Hereditary Angioedema International Archives of Allergy and Immunology, May 17, 2013 Clinical Article

6 Recent Advances in Hereditary Angioedema Self-Administration Treatment: Summary of an International Hereditary Angioedema Expert Meeting International Archives of Allergy and Immunology, May 17, 2013 Review Article

7 Celiac Disease and Autoimmunity: Review and Controversies Current Allergy and Asthma Reports, May 17, 2013 Review Article

8 Flow Cytometric Assay Detecting Cytotoxicity against Human Endogenous Retrovirus Antigens Expressed on Cultured Multiple Sclerosis Cells Clinical and Experimental Immunology, May 17, 2013 Clinical Article

9 Atrial fibrillation - inflammation in disguise? Scandinavian Journal of Immunology, May 17, 2013 Review Article

10 Diagnosis and Prevalence of Lanolin Allergy Dermatitis, May 17, 2013 Clinical Article

11 Pragmatism and the Evaluation of Metal Hypersensitivity Reactions Dermatitis, May 17, 2013 Review Article

12 Association between hepatic steatosis and hepatic expression of genes involved in innate immunity in patients with chronic hepatitis C Cytokine, May 17, 2013 Clinical Article

13 CD4 T Cell Responses in Latent and Chronic Viral Infections Frontiers in Immunology, May 17, 2013 Review Article

Prior Articles

14 Anti-viral agents: potential utility in exacerbations of asthma Current Opinion in Pharmacology , May 16, 2013 Review Article

15 Elevated levels of leukotriene C4 synthase mRNA distinguish a subpopulation of eosinophilic oesophagitis patients Clinical & Experimental Allergy, May 16, 2013 Clinical Article

16 The Coexistence of Asthma and Chronic Obstructive Pulmonary Disease (COPD): Prevalence and Risk Factors in Young, Middle-aged and Elderly People from the General Population PLOS ONE, May 16, 2013 Clinical Article

17 Clinical Routine Utility of Basophil Activation Testing for Diagnosis of Hymenoptera-Allergic Patients with Emphasis on Individuals with Negative Venom-Specific IgE Antibodies International Archives of Allergy and Immunology, May 16, 2013 Clinical Article

18 Different kinetics of circulating antibody-secreting cell responses after primary and booster oral immunizations: A tool for assessing immunological memory Vaccine , May 16, 2013 Clinical Article

19 Tolerogenic Dendritic Cells as a Therapy for Treating Lupus Clinical Immunology, May 16, 2013 Review Article

20 Differential effects of genetic susceptibility factors in males and females with multiple sclerosis Clinical Immunology, May 16, 2013 Review Article

50 available pages FirstPrevious 1 2 3 4 5 6 7 8 9 10 Next Last

Clinical Pearls in Internal Medicine

Vitamin D deficiency is more common with non-Caucasian patients, and those with lower social support, no insurance, diabetes, lower activity levels, higher parathyroid hormone levels, and higher body mass indexes
Eating an early breakfast and dinner when taking PPIs can lower FSSG scores and improve GERD symptoms. (Factors leading to increased FSSG scores were female gender, inadequate sleep, lack of breakfast, antihypertensive agent non-users and dinner just before bedtime.)
No single method of contraception is contraindicated by age alone, but caution should be exercised with estrogen-containing preparations in obese women over 40

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Highlights in Internal Medicine

Vitamin D deficiency is associated with increased mortality in ICU patients

Among 130 patients requiring mechanical ventilation, 107 were vitamin D-deficient (< 20 ng/ml). Of the patients who did not survive, the length of survival was shorter in the vitamin D-deficient patients (15.3 vs. 24.2 days, respectively).

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Coronary artery calcium increases cardiovascular risk in patients with T2DM and HTN

Researchers at Tel-Aviv University have conducted a study to determine the value of coronary artery calcium (CAC) measurements in cardiovascular risk stratification in patients with T2DM and HTN. The study involved 423 patients enrolled in the International Nifedipine Study: Intervention as Goal for Hypertension Therapy. The patients had baseline CT scans for CAC measurement at baseline and were shown to be free of disease. Follow-up CT scans were performed at 3 and 15 years. Cardiovascular events (CVEs) occurred in 41 of 423 patients at 3 years and 111 of 268 patients at 15 years of follow-up. CVEs occurred in 15% and 52% (CAC+) and 7% and 32% (CAC-) of patients with T2DM at 3 and 15 years of follow-up, respectively. Compared to patients without T2DM and no CAC, the HRs for a CVE were 6.6 and 3.9 in T2DM patients with and without CAC, respectively.

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CAC scores add predictability to Framingham

Researchers at Erasmus University Medical Center in Rotterdam have evaluated 12 measures (N-terminal fragment of prohormone B-type natriuretic peptide levels, von Willebrand factor antigen levels, fibrinogen levels, chronic kidney disease, leukocyte count, C-reactive protein levels, homocysteine levels, uric acid levels, coronary artery calcium [CAC] scores, carotid intima–media thickness, peripheral arterial disease, and pulse wave velocity), in addition to Framingham risk scores for predicting coronary heart disease. Only the CAC was shown to add significantly to the Framingham risk score in predicting coronary heart disease.

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Most Popular Internal Medicine Articles

Last month's top read Top Articles of 2012

1 Sublingual immunotherapy in southern Africa: Lessons learned The Journal of Allergy and Clinical Immunology, April 18, 2013 Review Article

2 Vitamin D effects on musculoskeletal health, immunity, autoimmunity, cardiovascular disease, cancer, fertility, pregnancy, dementia and mortality- a review of recent evidence Autoimmunity Reviews, April 4, 2013
Exclusive Author Commentary

3 Fungal rhinosinusitis: what every allergist should know Clinical & Experimental Allergy, March 27, 2013

4 Update on polymyalgia rheumatica European Journal of Internal Medicine , April 12, 2013

5 Inheritance of autoinflammatory diseases: shifting paradigms and nomenclature Journal of Medical Genetics, April 16, 2013 Review Article

6 Phosphodiesterase 4-targeted treatments for autoimmune diseases BMC Medicine, April 9, 2013 Free full text

7 Safely Diagnosing Clinically Significant Penicillin Allergy Using Only Penicilloyl-Poly-Lysine, Penicillin, and Oral Amoxicillin The Journal of Allergy and Clinical Immunology: In Practice, April 11, 2013

8 Exhaled nitric oxide indicates poorly athletes asthma The Clinical Respiratory Journal, April 9, 2013

9 Dehydrated egg white: An allergen source for improving efficacy and safety in the diagnosis and treatment for egg allergy Pediatric Allergy and Immunology, April 5, 2013

10 Distribution of peanut protein in the home environment The Journal of Allergy and Clinical Immunology, April 23, 2013 Review Article

11 Three phenotypes of adult-onset asthma Allergy, April 19, 2013 Review Article

12 Regular treatment with salmeterol and inhaled steroids for chronic asthma: serious adverse events Cochrane Reviews, April 2, 2013 Review Article

13 Impact of intranasal corticosteroids on asthma outcomes in allergic rhinitis: a meta-analysis Allergy, April 19, 2013

14 Mucosal Cytokine Response After Short-Term Gluten Challenge in Celiac Disease and Non-Celiac Gluten Sensitivity The American Journal of Gastroenterology, April 17, 2013

15 Limited role of allergy testing in patients with eosinophilic gastrointestinal disorders Journal of Gastroenterology and Hepatology, March 26, 2013 Review Article

16 Clinical value of radiocontrast media skin tests as a prescreening and diagnostic tool in hypersensitivity reactions Annals of Allergy, Asthma, and Immunology, March 28, 2013

17 Sublingual Immunotherapy for the Treatment of Allergic Rhinoconjunctivitis and Asthma: A Systematic Review JAMA, March 27, 2013 Evidence Based Medicine

18 Effects of 24-week add-on treatment with ciclesonide and montelukast on small airways inflammation in asthma Annals of Allergy, Asthma, and Immunology, March 12, 2013

19 Vitamin D in allergic disease: Shedding light on a complex problem The Journal of Allergy and Clinical Immunology, February 19, 2013 Review Article

20 Ciclesonide versus other inhaled corticosteroids for chronic asthma in children Cochrane Reviews, March 7, 2013 Review Article

Indexed Journals in Internal Medicine: New England Journal of Medicine, The Lancet, Archives of Internal Medicine more

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Internal Medicine - Allergy/Immunology News & Articles

Articles

Prior Articles

Clinical Pearls in Internal Medicine

Highlights in Internal Medicine

Vitamin D deficiency is associated with increased mortality in ICU patients

Coronary artery calcium increases cardiovascular risk in patients with T2DM and HTN

CAC scores add predictability to Framingham

Most Popular Internal Medicine Articles

Other Topics in Internal Medicine