Internal Medicine - Hematology/Oncology News & Articles

What makes MDLinx Internal Medicine different from all the other primary care literature reviews? Our team of medical editors read over 2,000 medical journals every day so you can stay current in less than 5 minutes! They sort, rank and summarize every article that will impact your daily practice. They even mark which articles are available in free full text, which are clinical or evidence-based, and which have MDLinx Exclusive Author Commentary from the people who actually performed the research.

Also on this page you’ll see bonus content from our physician editor, D. Scott Cunningham, MD, PhD, in the form of his top highlights you can’t miss, along with clinical pearls from The Smartest Internist, a quiz competition from the editors of MDLinx Internal Medicine in collaboration with the Cleveland Clinic Center for Continuing Education.

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Articles

Latest (39) Full Text Articles (1465) Focus on Diabetes Mellitus

Ranked, sorted, and summarized by MDLinx editors from the latest literature

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101 Short-course radiotherapy followed by neo-adjuvant chemotherapy in locally advanced rectal cancer-the RAPIDO trial Full Text BMC Cancer, June 17, 2013 Clinical Article

102 Cancer survivors in Switzerland: a rapidly growing population to care for Full Text BMC Cancer, June 17, 2013 Review Article

103 SB365, Pulsatilla saponin D, targets c-Met and exerts antiangiogenic and antitumor activities Carcinogenesis, June 17, 2013 Clinical Article

104 PTTG1 promotes migration and invasion of human non-small cell lung cancer cells and is modulated by miR-186 Carcinogenesis, June 17, 2013 Clinical Article

105 Antitumor activity of semisynthetic derivatives of Aconitum alkaloids Investigational New Drugs, June 17, 2013 Clinical Article

106 Cardiac glycosides in cancer therapy: from preclinical investigations towards clinical trials Investigational New Drugs, June 17, 2013 Clinical Article

107 Prostate cancer progression after androgen deprivation therapy: mechanisms of castrate resistance and novel therapeutic approaches Oncogene, June 17, 2013 Review Article Clinical Article

108 Polymorphisms in the F8 gene and MHC-II variants as risk factors for the development of inhibitory anti-factor VIII antibodies during the treatment of hemophilia A: A computational assessment Full Text PLoS Neglected Tropical Diseases, June 17, 2013

109 Improving breast cancer survival analysis through competition-based multidimensional modeling Full Text PLoS Neglected Tropical Diseases, June 17, 2013 Clinical Article

110 Perceptions about preventing hepatocellular carcinoma among patients with chronic hepatitis in Taiwan Full Text World Journal of Gastroenterology, June 17, 2013 Clinical Article

111 Incidental focal colorectal ¹⁸F-fluorodeoxyglucose uptake on positron emission tomography/computed tomography Full Text World Journal of Gastroenterology, June 17, 2013 Review Article

112 RAS/MEK–independent gene expression reveals BMP2-related malignant phenotypes in the NF1-deficient MPNST Molecular Cancer Research, June 17, 2013 Clinical Article

113 AURKA maintains self-renewal in glioma-initiating cells through the stabilization of {beta}-catenin and activation of Wnt signaling Molecular Cancer Research, June 17, 2013 Clinical Article

114 Prognostic role of bone sialoprotein in clear cell renal carcinoma Anticancer Research, June 17, 2013 Review Article

115 Incidence and survival in sarcoma in the United States: a focus on musculoskeletal lesions Anticancer Research, June 17, 2013 Review Article Clinical Article

116 Alcohol and HER2 Polymorphisms as Risk Factor for Cardiotoxicity in Breast Cancer Treated with Trastuzumab Anticancer Research, June 17, 2013 Clinical Article

117 Cannabinoid receptor agonist as an alternative drug in 5-fluorouracil-resistant gastric cancer cells Anticancer Research, June 17, 2013 Clinical Article

118 Changes in thymidine phosphorylase gene expression related to treatment of rectal cancer Anticancer Research, June 17, 2013 Clinical Article

119 Nx-PVKAlevels before and after hepatectomy of hepatocellular carcinoma as predictors of patient survival: a preliminary evaluation of an improved assay for pIVKA-II Anticancer Research, June 17, 2013 Clinical Article

120 Can high-spatial resolution T2-weighted endorectal MRI rule out clinically significant prostate cancer? World Journal of Urology, June 17, 2013 Clinical Article

50 available pages First Previous 6 7 8 9 10 11 12 13 14 15 Next Last

Clinical Pearls in Internal Medicine

Vitamin D deficiency is more common with non-Caucasian patients, and those with lower social support, no insurance, diabetes, lower activity levels, higher parathyroid hormone levels, and higher body mass indexes
Eating an early breakfast and dinner when taking PPIs can lower FSSG scores and improve GERD symptoms. (Factors leading to increased FSSG scores were female gender, inadequate sleep, lack of breakfast, antihypertensive agent non-users and dinner just before bedtime.)
No single method of contraception is contraindicated by age alone, but caution should be exercised with estrogen-containing preparations in obese women over 40

» Test your knowledge. Take the Smartest Doc challenge today!

Highlights in Internal Medicine

Vitamin D deficiency is associated with increased mortality in ICU patients

Among 130 patients requiring mechanical ventilation, 107 were vitamin D-deficient (< 20 ng/ml). Of the patients who did not survive, the length of survival was shorter in the vitamin D-deficient patients (15.3 vs. 24.2 days, respectively).

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Coronary artery calcium increases cardiovascular risk in patients with T2DM and HTN

Researchers at Tel-Aviv University have conducted a study to determine the value of coronary artery calcium (CAC) measurements in cardiovascular risk stratification in patients with T2DM and HTN. The study involved 423 patients enrolled in the International Nifedipine Study: Intervention as Goal for Hypertension Therapy. The patients had baseline CT scans for CAC measurement at baseline and were shown to be free of disease. Follow-up CT scans were performed at 3 and 15 years. Cardiovascular events (CVEs) occurred in 41 of 423 patients at 3 years and 111 of 268 patients at 15 years of follow-up. CVEs occurred in 15% and 52% (CAC+) and 7% and 32% (CAC-) of patients with T2DM at 3 and 15 years of follow-up, respectively. Compared to patients without T2DM and no CAC, the HRs for a CVE were 6.6 and 3.9 in T2DM patients with and without CAC, respectively.

Read the article summary

CAC scores add predictability to Framingham

Researchers at Erasmus University Medical Center in Rotterdam have evaluated 12 measures (N-terminal fragment of prohormone B-type natriuretic peptide levels, von Willebrand factor antigen levels, fibrinogen levels, chronic kidney disease, leukocyte count, C-reactive protein levels, homocysteine levels, uric acid levels, coronary artery calcium [CAC] scores, carotid intima–media thickness, peripheral arterial disease, and pulse wave velocity), in addition to Framingham risk scores for predicting coronary heart disease. Only the CAC was shown to add significantly to the Framingham risk score in predicting coronary heart disease.

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Most Popular Internal Med Articles

Last month's top read Top Articles of 2012

1 The relationship between nutrition and prostate cancer: is more always better? European Urology, May 3, 2013 Free full text Review Article

2 The New Oral Anticoagulants in Clinical Practice Mayo Clinic Proceedings, May 13, 2013

3 Dietary fiber and the risk of precancerous lesions and cancer of the esophagus: a systematic review and meta-analysis Nutrition Reviews, April 30, 2013 Evidence Based Medicine Review Article

4 Obesity and prostate cancer: weighing the evidence European Urology, May 3, 2013 Free full text Review Article

5 Strategy for detection of prostate cancer based on relation between prostate specific antigen at age 40-55 and long term risk of metastasis: case-control study British Medical Journal, April 23, 2013

6 Egg consumption and risk of bladder cancer: a meta-analysis Nutrition and Cancer, May 17, 2013

7 Risk of a Second Primary Cancer after Non-melanoma Skin Cancer in White Men and Women: A Prospective Cohort Study PLoS Medicine, May 6, 2013 Free full text

8 IRON-HF study: A randomized trial to assess the effects of iron in heart failure patients with anemia International Journal of Cardiology, May 20, 2013

9 Ultrasonography in prostate cancer: current roles and potential applications in radiorecurrent disease World Journal of Urology, May 7, 2013

10 Coffee and caffeine intake and breast cancer risk: An updated dose-response meta-analysis of 37 published studies Gynecologic Oncology, May 10, 2013 Evidence Based Medicine

11 Guidelines on Management of Prostate Cancer Annals, Academy of Medicine, Singapore, May 8, 2013 Free full text Clinical Guideline

12 Results of initial low-dose computed tomographic screening for lung cancer New England Journal of Medicine, May 24, 2013 Evidence Based Medicine

13 Leukaemia update. Part 1: diagnosis and management British Medical Journal, April 9, 2013 Review Article

14 New Perspectives of Curcumin in Cancer Prevention Cancer Prevention Research, April 17, 2013 Review Article

15 Cidofovir selectivity is based on the different response of normal and cancer cells to DNA damage BMC Genomics, May 28, 2013 Free full text

16 Breast cancer detection and survival among women with cosmetic breast implants: systematic review and meta-analysis of observational studies British Medical Journal, May 8, 2013 Evidence Based Medicine

17 A low dietary ratio of omega-6 to omega-3 fatty acids may delay progression of prostate cancer Nutrition and Cancer, May 20, 2013

18 The immunomodulatory and anticancer properties of propolis Clinical Reviews in Allergy and Immunology, May 8, 2013 Review Article

19 Pacemaker or Defibrillator Surgery without Interruption of Anticoagulation New England Journal of Medicine, May 17, 2013 Evidence Based Medicine

20 Treatment of Iron-deficiency Anemia in Patients with Subclinical Hypothyroidism American Journal of Medicine, April 18, 2013

Indexed Journals in Internal Medicine: New England Journal of Medicine, The Lancet, Archives of Internal Medicine more

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Internal Medicine - Hematology/Oncology News & Articles

Articles

Clinical Pearls in Internal Medicine

Highlights in Internal Medicine

Vitamin D deficiency is associated with increased mortality in ICU patients

Coronary artery calcium increases cardiovascular risk in patients with T2DM and HTN

CAC scores add predictability to Framingham

Most Popular Internal Med Articles

Other Topics in Internal Medicine