What makes MDLinx Internal Medicine different from all the other primary care literature reviews? Our team of medical editors read over 2,000 medical journals every day so you can stay current in less than 5 minutes! They sort, rank and summarize every article that will impact your daily practice. They even mark which articles are available in free full text, which are clinical or evidence-based, and which have MDLinx Exclusive Author Commentary from the people who actually performed the research.
Also on this page you’ll see bonus content from our physician editor, D. Scott Cunningham, MD, PhD, in the form of his top highlights you can’t miss, along with clinical pearls from The Smartest Internist, a quiz competition from the editors of MDLinx Internal Medicine in collaboration with the Cleveland Clinic Center for Continuing Education.
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981 Multi-Ethnic Study of Atherosclerosis Arterial Age Versus Framingham 10-Year or Lifetime Cardiovascular Risk The American Journal of Cardiology, November 19, 2012 Clinical Article
982 Relationship between serum parathyroid hormone levels and lipid profile in non-diabetic hemodialysis patients Full Text Saudi Journal of Kidney Diseases and Transplantation, November 19, 2012
983 Preliminary evidence of genetic determinants of adiponectin response to fenofibrate in the Genetics of Lipid Lowering Drugs and Diet Network Nutrition, Metabolism & Cardiovascular Diseases, November 16, 2012 Evidence Based Medicine Clinical Article
984 Does Dairy Food Intake Predict Arterial Stiffness and Blood Pressure in Men? Evidence from the Caerphilly Prospective Study Hypertension, November 16, 2012 Clinical Article
985 Clinical research Lipid and protein oxidation in female patients with chronic fatigue syndrome Archives of Medical Science, November 16, 2012 Clinical Article
986 Migraine is not associated with enhanced atherosclerosis Cephalalgia, November 16, 2012 Clinical Article
987 Calcium intake is not associated with increased coronary artery calcification: the Framingham Study American Journal of Clinical Nutrition, November 16, 2012
988 Composition of fatty acids in the maternal and umbilical cord plasma of adolescent and adult mothers: relationship with anthropometric parameters of newborn Full Text Lipids in Health and Disease, November 16, 2012
989 Effect of Gender, Caregiver, on Cholesterol Control and Statin Use for Secondary Prevention Among Hospitalized Patients With Coronary Heart Disease The American Journal of Cardiology, November 15, 2012 Clinical Article
990 CKD, Plasma Lipids, and Common Carotid Intima-Media Thickness: Results from the Multi-Ethnic Study of Atherosclerosis Clinical Journal of the American Society of Nephrology, November 15, 2012 Clinical Article
991 Urokinase receptor surface expression regulates monocyte migration and is associated with accelerated atherosclerosis International Journal of Cardiology, November 15, 2012
992 Neck circumference is correlated with triglycerides and inversely related with HDL-cholesterol beyond BMI and waist circumference Diabetes/Metabolism Research and Reviews, November 15, 2012
993 Screening for chronic kidney disease can be of help to prevent atherosclerotic end organ damage Nephrology Dialysis Transplantation, November 14, 2012
994 Contribution of education level and dairy fat sources to serum cholesterol in Russian and Finnish Karelia: results from four cross-sectional risk factor surveys in 1992-2007 Full Text BMC Public Health, November 12, 2012
995 Efficacy, safety, and tolerability of a monoclonal antibody to proprotein convertase subtilisin/kexin type 9 as monotherapy in patients with hypercholesterolaemia (MENDEL): a randomised, double-blind, placebo-controlled, phase 2 study The Lancet - Early Online Publication, November 8, 2012 Clinical Article
996 Efficacy, safety, and tolerability of a monoclonal antibody to proprotein convertase subtilisin/kexin type 9 in combination with a statin in patients with hypercholesterolaemia (LAPLACE-TIMI 57): a randomised, placebo-controlled, dose-ranging, phase 2 study The Lancet - Early Online Publication, November 8, 2012 Clinical Article
997 ABCA1 mutation carriers with low high-density lipoprotein cholesterol are characterized by a larger atherosclerotic burden European Heart Journal, November 8, 2012 Clinical Article
998 Basic Study of a Mixture of N-butyl Cyanoacrylate, Ethanol, and Lipiodol as a New Embolic Material Journal of Vascular and Interventional Radiology, November 8, 2012
999 Fenofibrate Improves Vascular Endothelial Function by Reducing Oxidative Stress While Increasing Endothelial Nitric Oxide Synthase in Healthy Normolipidemic Older Adults Hypertension, November 7, 2012 Clinical Article
1000 Hyperlipidemia, oxidative stress, and intima media thickness in children with chronic kidney disease Pediatric Nephrology, November 7, 2012
Among 130 patients requiring mechanical ventilation, 107 were vitamin D-deficient (< 20 ng/ml). Of the patients who did not survive, the length of survival was shorter in the vitamin D-deficient patients (15.3 vs. 24.2 days, respectively).
Read the article summaryResearchers at Tel-Aviv University have conducted a study to determine the value of coronary artery calcium (CAC) measurements in cardiovascular risk stratification in patients with T2DM and HTN. The study involved 423 patients enrolled in the International Nifedipine Study: Intervention as Goal for Hypertension Therapy. The patients had baseline CT scans for CAC measurement at baseline and were shown to be free of disease. Follow-up CT scans were performed at 3 and 15 years. Cardiovascular events (CVEs) occurred in 41 of 423 patients at 3 years and 111 of 268 patients at 15 years of follow-up. CVEs occurred in 15% and 52% (CAC+) and 7% and 32% (CAC-) of patients with T2DM at 3 and 15 years of follow-up, respectively. Compared to patients without T2DM and no CAC, the HRs for a CVE were 6.6 and 3.9 in T2DM patients with and without CAC, respectively.
Read the article summaryResearchers at Erasmus University Medical Center in Rotterdam have evaluated 12 measures (N-terminal fragment of prohormone B-type natriuretic peptide levels, von Willebrand factor antigen levels, fibrinogen levels, chronic kidney disease, leukocyte count, C-reactive protein levels, homocysteine levels, uric acid levels, coronary artery calcium [CAC] scores, carotid intima–media thickness, peripheral arterial disease, and pulse wave velocity), in addition to Framingham risk scores for predicting coronary heart disease. Only the CAC was shown to add significantly to the Framingham risk score in predicting coronary heart disease.
Read the article summary1 Walking Versus Running for Hypertension, Cholesterol, and Diabetes Mellitus Risk Reduction Arteriosclerosis, Thrombosis, and Vascular Biology, April 17, 2013
2 Role of exercise in the prevention of cardiovascular disease: results, mechanisms, and new perspectives European Heart Journal, April 11, 2013
3 Renin-angiotensin system inhibitors for prevention of recurrent atrial fibrillation: a meta-analysis International Journal of Clinical Practice, April 9, 2013 Evidence Based Medicine Review Article
4 L-Carnitine in the Secondary Prevention of Cardiovascular Disease: Systematic Review and Meta-analysis Mayo Clinic Proceedings, April 19, 2013 Evidence Based Medicine Review Article
5 Six-Minute Walk Test: An Effective and Necessary Tool in Modern Cardiac Rehabilitation The Hellenic Journal of Cardiology, April 16, 2013 Free full text Review Article
6 Mortality and Morbidity During and After Antihypertensive and Lipid-Lowering Treatment to Prevent Heart Attack Trial Hypertension, April 19, 2013
7 Effect of seven-day atorvastatin pretreatment on the incidence of periprocedural myocardial infarction following percutaneous coronary intervention in patients receiving long-term statin therapy. A randomized study International Journal of Cardiology, April 19, 2013
8 The Importance of 24-Hour Ambulatory Blood Pressure Monitoring in Patients at Risk of Cardiovascular Events High Blood Pressure & Cardiovascular Prevention, April 16, 2013
9 Is Overweight a Risk of Early Atherosclerosis in Childhood? Angiology, February 28, 2013
10 Cholesterol and prostate cancer Current Opinion in Pharmacology , February 4, 2013
11
Vitamin D Levels for Preventing Acute Coronary Syndrome and Mortality: Evidence of a Non-Linear Association
Journal of Clinical Endocrinology and Metabolism, March 27, 2013
Exclusive Author Commentary
12 Omega-3 fatty acids: Benefits for cardio-cerebro-vascular diseases Atherosclerosis, December 5, 2012
13 Oxygen therapy in acute coronary syndrome: are the benefits worth the risk? European Heart Journal, April 8, 2013 Review Article
14 Primary Prevention of Cardiovascular Disease with a Mediterranean Diet New England Journal of Medicine, April 8, 2013 Free full text
15 Testosterone and cardiovascular risk Internal and Emergency Medicine, March 21, 2013
16 Chlorthalidone Versus Hydrochlorothiazide for the Treatment of Hypertension in Older Adults A Population-Based Cohort Study Annals of Internal Medicine, March 19, 2013
17 Cell Therapy of Peripheral Arterial Disease Circulation Research, April 29, 2013
18 Cardiovascular events after clarithromycin use in lower respiratory tract infections: analysis of two prospective cohort studies British Medical Journal, April 10, 2013 Free full text
19
The endocrinology of exercise
Internal and Emergency Medicine, March 27, 2013
Review Article
Exclusive Author Commentary
20 Coronary artery bypass graft surgery versus percutaneous coronary intervention in patients with three-vessel disease and left main coronary disease: 5-year follow-up of the randomised, clinical SYNTAX trial The Lancet, April 18, 2013
Indexed Journals in Internal Medicine: New England Journal of Medicine, The Lancet, Archives of Internal Medicine more
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