Internal Medicine - Atherosclerosis/Lipids News & Articles

What makes MDLinx Internal Medicine different from all the other primary care literature reviews? Our team of medical editors read over 2,000 medical journals every day so you can stay current in less than 5 minutes! They sort, rank and summarize every article that will impact your daily practice. They even mark which articles are available in free full text, which are clinical or evidence-based, and which have MDLinx Exclusive Author Commentary from the people who actually performed the research.

Also on this page you’ll see bonus content from our physician editor, D. Scott Cunningham, MD, PhD, in the form of his top highlights you can’t miss, along with clinical pearls from The Smartest Internist, a quiz competition from the editors of MDLinx Internal Medicine in collaboration with the Cleveland Clinic Center for Continuing Education.

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Articles

Latest (9) Full Text Articles (258) Focus on HIV

Ranked, sorted, and summarized by MDLinx editors from the latest literature

Topics:

61 Relationship between central and peripheral fatty acids in humans Full Text Lipids in Health and Disease, May 31, 2013

62 Delta-6-desaturase gene polymorphism is associated with lipoprotein oxidation in vitro Full Text Lipids in Health and Disease, May 31, 2013

63 Cyclic restricted feeding enhances lipid storage in 3 T3-L1 adipocytes Full Text Lipids in Health and Disease, May 31, 2013

64 Level of serum antibody against a periodontal pathogen is associated with atherosclerosis and hypertension Hypertension Research, May 31, 2013 Clinical Article

65 Relation between aortic valve sclerosis and ankle-brachial index in participants clinically free of atherosclerotic vascular disease Angiology, May 31, 2013 Review Article

66 Relationship between mean platelet volume and atherosclerosis in young patients with st elevation myocardial infarction Angiology, May 31, 2013 Review Article Clinical Article

67 LDL oxidation and its association with carotid artery intima-media thickness and other cardiovascular risk factors in a sample of spanish general population Angiology, May 31, 2013 Review Article Clinical Article

68 Statins and lipid metabolism Current Opinion in Lipidology, May 30, 2013 Review Article Clinical Article

69 Lack of protective role of HDL-C in patients with coronary artery disease undergoing elective coronary artery bypass grafting European Heart Journal, May 29, 2013 Clinical Article

70 Screening for subclinical atherosclerosis by noninvasive methods in asymptomatic patients with risk factors Full Text Clinical Interventions in Aging, May 29, 2013 Review Article

71 Recent advances in niacin and lipid metabolism Current Opinion in Lipidology, May 29, 2013 Review Article

72 Hypoxia enhances lipid uptake in macrophages: Role of the scavenger receptors Lox1, SRA, and CD36 Atherosclerosis, May 29, 2013 Clinical Article

73 Renal function and short-term outcome in stable outpatients with coronary, cerebrovascular or peripheral artery disease Atherosclerosis, May 29, 2013 Clinical Article

74 How to assess non-calcified plaque in CT angiography: delineation methods affect diagnostic accuracy of low-attenuation plaque by CT for lipid-core plaque in histology European Heart Journal – Cardiovascular Imaging, May 29, 2013 Clinical Article

75 Calcium–phosphorus product concentration is a risk factor of coronary artery disease in metabolic syndrome Atherosclerosis, May 28, 2013 Review Article

76 Gender-specific association of coronary artery calcium and lipoprotein parameters: The Heinz Nixdorf Recall Study Atherosclerosis, May 28, 2013 Clinical Article

77 Mrna-binding protein ZFP36 is expressed in atherosclerotic lesions and reduces inflammation in aortic endothelial cells Arteriosclerosis, Thrombosis, and Vascular Biology, May 28, 2013 Clinical Article

78 Liver X receptor regulates arachidonic acid distribution and eicosanoid release in human macrophages Arteriosclerosis, Thrombosis, and Vascular Biology, May 28, 2013 Clinical Article

79 Diesel exhaust induces systemic lipid peroxidation and development of dysfunctional pro-oxidant and pro-inflammatory high-density lipoprotein Arteriosclerosis, Thrombosis, and Vascular Biology, May 28, 2013 Clinical Article

80 Hypoxia Induces Netrin-1 and Unc5b in Atherosclerotic Plaques Arteriosclerosis, Thrombosis, and Vascular Biology, May 28, 2013 Clinical Article

50 available pages First Previous 4 5 6 7 8 9 10 11 12 13 Next Last

Clinical Pearls in Internal Medicine

Vitamin D deficiency is more common with non-Caucasian patients, and those with lower social support, no insurance, diabetes, lower activity levels, higher parathyroid hormone levels, and higher body mass indexes
Eating an early breakfast and dinner when taking PPIs can lower FSSG scores and improve GERD symptoms. (Factors leading to increased FSSG scores were female gender, inadequate sleep, lack of breakfast, antihypertensive agent non-users and dinner just before bedtime.)
No single method of contraception is contraindicated by age alone, but caution should be exercised with estrogen-containing preparations in obese women over 40

» Test your knowledge. Take the Smartest Doc challenge today!

Highlights in Internal Medicine

Vitamin D deficiency is associated with increased mortality in ICU patients

Among 130 patients requiring mechanical ventilation, 107 were vitamin D-deficient (< 20 ng/ml). Of the patients who did not survive, the length of survival was shorter in the vitamin D-deficient patients (15.3 vs. 24.2 days, respectively).

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Coronary artery calcium increases cardiovascular risk in patients with T2DM and HTN

Researchers at Tel-Aviv University have conducted a study to determine the value of coronary artery calcium (CAC) measurements in cardiovascular risk stratification in patients with T2DM and HTN. The study involved 423 patients enrolled in the International Nifedipine Study: Intervention as Goal for Hypertension Therapy. The patients had baseline CT scans for CAC measurement at baseline and were shown to be free of disease. Follow-up CT scans were performed at 3 and 15 years. Cardiovascular events (CVEs) occurred in 41 of 423 patients at 3 years and 111 of 268 patients at 15 years of follow-up. CVEs occurred in 15% and 52% (CAC+) and 7% and 32% (CAC-) of patients with T2DM at 3 and 15 years of follow-up, respectively. Compared to patients without T2DM and no CAC, the HRs for a CVE were 6.6 and 3.9 in T2DM patients with and without CAC, respectively.

Read the article summary

CAC scores add predictability to Framingham

Researchers at Erasmus University Medical Center in Rotterdam have evaluated 12 measures (N-terminal fragment of prohormone B-type natriuretic peptide levels, von Willebrand factor antigen levels, fibrinogen levels, chronic kidney disease, leukocyte count, C-reactive protein levels, homocysteine levels, uric acid levels, coronary artery calcium [CAC] scores, carotid intima–media thickness, peripheral arterial disease, and pulse wave velocity), in addition to Framingham risk scores for predicting coronary heart disease. Only the CAC was shown to add significantly to the Framingham risk score in predicting coronary heart disease.

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Most Popular Internal Med Articles

Last month's top read Top Articles of 2012

1 Factors underlying regression of coronary atheroma with potent statin therapy European Heart Journal, May 6, 2013

2 Anti-Inflammatory Strategies for Plaque Stabilization after Acute Coronary Syndromes Current Atherosclerosis Reports, May 21, 2013

3 Anger and the Heart: Perspectives on Cardiac Risk, Mechanisms and Interventions Progress in Cardiovascular Diseases , May 1, 2013

4 Effect of longer term modest salt reduction on blood pressure: Cochrane systematic review and meta-analysis of randomised trials British Medical Journal, April 25, 2013 Evidence Based Medicine Review Article

5 Two-Year Outcomes for Patients With Severe Symptomatic Aortic Stenosis Treated With Transcatheter Aortic Valve Implantation The American Journal of Cardiology, April 29, 2013

6 Oxidized eicosapentaenoic acids more potently reduce LXRalpha-induced cellular triacylglycerol via suppression of SREBP-1c, PGC-1beta and GPA than its intact form Lipids in Health and Disease, May 21, 2013 Free full text

7 The Effects of Ezetimibe/Simvastatin versus Simvastatin Monotherapy on Platelet and Inflammatory Biomarkers in Patients with Metabolic Syndrome Cardiology, May 9, 2013

8 Statins and lipid metabolism Current Opinion in Lipidology, May 24, 2013 Review Article

9 Competing Cardiovascular Outcomes Associated With Subclinical Atherosclerosis (from the Multi-Ethnic Study of Atherosclerosis) The American Journal of Cardiology, May 16, 2013

10 Association between habitual physical activity and lower cardiovascular risk in premenopausal, perimenopausal, and postmenopausal women: a population-based study Menopause, April 26, 2013

11 Renin-angiotensin system inhibitors for prevention of recurrent atrial fibrillation: a meta-analysis International Journal of Clinical Practice, April 9, 2013 Evidence Based Medicine Review Article

12 Combined non-invasive functional and anatomical diagnostic work-up in clinical practice: the magnetic resonance and computed tomography in suspected coronary artery disease (MARCC) study European Heart Journal, April 29, 2013

13 Effects of rosuvastatin versus atorvastatin on small dense low-density lipoprotein: a meta-analysis of randomized trials Heart and Vessels, May 8, 2013 Evidence Based Medicine Review Article

14 Dietary fatty acids and lipoprotein metabolism: new insights and updates Current Opinion in Lipidology, May 24, 2013 Review Article

15 Impact of Adding Ezetimibe to Statin to Achieve Low-Density Lipoprotein Cholesterol Goal (from the Clinical Outcomes Utilizing Revascularization and Aggressive Drug Evaluation [COURAGE] Trial) The American Journal of Cardiology, May 17, 2013

16 Role of exercise in the prevention of cardiovascular disease: results, mechanisms, and new perspectives European Heart Journal, April 11, 2013

17 Age-dependent interaction of apolipoprotein E gene with eastern birthplace in Finland affects severity of coronary atherosclerosis and risk of fatal myocardial infarction-Helsinki Sudden Death Study Annals of Medicine, May 22, 2013 Evidence Based Medicine

18 Walking Versus Running for Hypertension, Cholesterol, and Diabetes Mellitus Risk Reduction Arteriosclerosis, Thrombosis, and Vascular Biology, April 17, 2013

19 Computed tomography-derived cardiovascular risk markers, incident cardiovascular events, and all-cause mortality in nondiabetics: the Multi-Ethnic Study of Atherosclerosis European Journal of Preventive Cardiology, May 22, 2013
Exclusive Author Commentary

20 Six-Minute Walk Test: An Effective and Necessary Tool in Modern Cardiac Rehabilitation The Hellenic Journal of Cardiology, April 16, 2013 Free full text Review Article

Indexed Journals in Internal Medicine: New England Journal of Medicine, The Lancet, Archives of Internal Medicine more

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Internal Medicine - Atherosclerosis/Lipids News & Articles

Articles

Clinical Pearls in Internal Medicine

Highlights in Internal Medicine

Vitamin D deficiency is associated with increased mortality in ICU patients

Coronary artery calcium increases cardiovascular risk in patients with T2DM and HTN

CAC scores add predictability to Framingham

Most Popular Internal Med Articles

Other Topics in Internal Medicine