Internal Medicine - Atherosclerosis/Lipids News & Articles

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Ranked, sorted, and summarized by MDLinx editors from the latest literature

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621 Association of Epicardial Fat With Cardiovascular Risk Factors and Incident Myocardial Infarction in the General Population The Heinz Nixdorf Recall Study Full Text JACC - Journal of the American College of Cardiology, March 13, 2013 Clinical Article

622 Clinical implications of JUPITER in a contemporary European population: the EPIC-Norfolk prospective population study European Heart Journal, March 4, 2013 Clinical Article

623 MRI of Carotid Atherosclerosis American Journal of Roentgenology, March 4, 2013 Clinical Article

624 Impact of genetic factors on dyslipidemia in HIV-infected patients starting antiretroviral therapy AIDS, March 4, 2013 Clinical Article

625 Early Detection of Subclinical Atherosclerosis in Asymptomatic Patients Assessed by Carotid Duplex and Coronary Computed Tomography Full Text International Journal of Gerontology, March 4, 2013 Review Article

626 Safety of Antidiabetic Therapies on Bone Clinical Reviews in Bone and Mineral Metabolism , March 1, 2013 Review Article

627 Diabetes mellitus is associated with adverse prognosis in chronic heart failure of ischaemic and non-ischaemic aetiology Diabetes & Vascular Disease Research, March 1, 2013 Clinical Article

628 Postmenopausal women with carotid atherosclerosis: Potential role of the serum calcium levels Nutrition, Metabolism & Cardiovascular Diseases, March 1, 2013 Clinical Article

629 Impaired Fasting Glucose and Impaired Glucose Tolerance Have Distinct Lipoprotein and Apolipoprotein Changes: The Insulin Resistance Atherosclerosis Study Journal of Clinical Endocrinology and Metabolism, March 1, 2013 Clinical Article

630 Severe Hypertriglyceridemia-Related Acute Pancreatitis Therapeutic Apheresis and Dialysis, March 1, 2013 Review Article

631 A comparison of efficacy and safety of an ezetimibe/simvastatin combination compared with other intensified lipid-lowering treatment strategies in diabetic patients with symptomatic cardiovascular disease Diabetes & Vascular Disease Research, February 28, 2013 Clinical Article

632 Do Statins Have a Role in the Prevention of Age-Related Macular Degeneration? Drugs & Aging, February 28, 2013 Clinical Article

633 The role of omega-3 derived resolvins in arthritis Current Opinion in Pharmacology , February 28, 2013 Clinical Guideline

634 Lipid management in 13,000 high risk cardiovascular patients treated under daily practice conditions: LIMA Registry Full Text Vascular Health and Risk Management, February 27, 2013 Clinical Article

635 Comparative effects of statins on major cerebrovascular events: a multiple-treatments meta-analysis of placebo-controlled and active-comparator trials QJM: An International Journal of Medicine, February 27, 2013 Review Article

636 An association of hyperglycemia with plasma malondialdehyde and atherogenic lipid risk factors in newly diagnosed Type 2 diabetic patients Journal of Research in Medical Sciences, February 27, 2013 Clinical Article

637 Kochujang, fermented soybean-based red pepper paste, decreases visceral fat and improves blood lipid profiles in overweight adults Full Text Nutrition & Metabolism, February 27, 2013 Review Article

638 Prevalence and control of dyslipidaemia among diabetic patients with microalbuminuria in a Chinese hospital Diabetes & Vascular Disease Research, February 26, 2013 Clinical Article

639 Statins and beyond: Concurrent strategies for prevention of cardiovascular disease in patients with type 2 diabetes Diabetes & Vascular Disease Research, February 26, 2013 Clinical Article

640 Use of low-density lipoprotein cholesterol gene score to distinguish patients with polygenic and monogenic familial hypercholesterolaemia: a case-control study The Lancet, February 22, 2013 Clinical Article

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Clinical Pearls in Internal Medicine

Vitamin D deficiency is more common with non-Caucasian patients, and those with lower social support, no insurance, diabetes, lower activity levels, higher parathyroid hormone levels, and higher body mass indexes
Eating an early breakfast and dinner when taking PPIs can lower FSSG scores and improve GERD symptoms. (Factors leading to increased FSSG scores were female gender, inadequate sleep, lack of breakfast, antihypertensive agent non-users and dinner just before bedtime.)
No single method of contraception is contraindicated by age alone, but caution should be exercised with estrogen-containing preparations in obese women over 40

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Highlights in Internal Medicine

Vitamin D deficiency is associated with increased mortality in ICU patients

Among 130 patients requiring mechanical ventilation, 107 were vitamin D-deficient (< 20 ng/ml). Of the patients who did not survive, the length of survival was shorter in the vitamin D-deficient patients (15.3 vs. 24.2 days, respectively).

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Coronary artery calcium increases cardiovascular risk in patients with T2DM and HTN

Researchers at Tel-Aviv University have conducted a study to determine the value of coronary artery calcium (CAC) measurements in cardiovascular risk stratification in patients with T2DM and HTN. The study involved 423 patients enrolled in the International Nifedipine Study: Intervention as Goal for Hypertension Therapy. The patients had baseline CT scans for CAC measurement at baseline and were shown to be free of disease. Follow-up CT scans were performed at 3 and 15 years. Cardiovascular events (CVEs) occurred in 41 of 423 patients at 3 years and 111 of 268 patients at 15 years of follow-up. CVEs occurred in 15% and 52% (CAC+) and 7% and 32% (CAC-) of patients with T2DM at 3 and 15 years of follow-up, respectively. Compared to patients without T2DM and no CAC, the HRs for a CVE were 6.6 and 3.9 in T2DM patients with and without CAC, respectively.

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CAC scores add predictability to Framingham

Researchers at Erasmus University Medical Center in Rotterdam have evaluated 12 measures (N-terminal fragment of prohormone B-type natriuretic peptide levels, von Willebrand factor antigen levels, fibrinogen levels, chronic kidney disease, leukocyte count, C-reactive protein levels, homocysteine levels, uric acid levels, coronary artery calcium [CAC] scores, carotid intima–media thickness, peripheral arterial disease, and pulse wave velocity), in addition to Framingham risk scores for predicting coronary heart disease. Only the CAC was shown to add significantly to the Framingham risk score in predicting coronary heart disease.

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Most Popular Internal Medicine Articles

Last month's top read Top Articles of 2012

1 Walking Versus Running for Hypertension, Cholesterol, and Diabetes Mellitus Risk Reduction Arteriosclerosis, Thrombosis, and Vascular Biology, April 17, 2013

2 Role of exercise in the prevention of cardiovascular disease: results, mechanisms, and new perspectives European Heart Journal, April 11, 2013

3 Renin-angiotensin system inhibitors for prevention of recurrent atrial fibrillation: a meta-analysis International Journal of Clinical Practice, April 9, 2013 Evidence Based Medicine Review Article

4 L-Carnitine in the Secondary Prevention of Cardiovascular Disease: Systematic Review and Meta-analysis Mayo Clinic Proceedings, April 19, 2013 Evidence Based Medicine Review Article

5 Six-Minute Walk Test: An Effective and Necessary Tool in Modern Cardiac Rehabilitation The Hellenic Journal of Cardiology, April 16, 2013 Free full text Review Article

6 Mortality and Morbidity During and After Antihypertensive and Lipid-Lowering Treatment to Prevent Heart Attack Trial Hypertension, April 19, 2013

7 Effect of seven-day atorvastatin pretreatment on the incidence of periprocedural myocardial infarction following percutaneous coronary intervention in patients receiving long-term statin therapy. A randomized study International Journal of Cardiology, April 19, 2013

8 The Importance of 24-Hour Ambulatory Blood Pressure Monitoring in Patients at Risk of Cardiovascular Events High Blood Pressure & Cardiovascular Prevention, April 16, 2013

9 Is Overweight a Risk of Early Atherosclerosis in Childhood? Angiology, February 28, 2013

10 Cholesterol and prostate cancer Current Opinion in Pharmacology , February 4, 2013

11 Vitamin D Levels for Preventing Acute Coronary Syndrome and Mortality: Evidence of a Non-Linear Association Journal of Clinical Endocrinology and Metabolism, March 27, 2013
Exclusive Author Commentary

12 Omega-3 fatty acids: Benefits for cardio-cerebro-vascular diseases Atherosclerosis, December 5, 2012

13 Oxygen therapy in acute coronary syndrome: are the benefits worth the risk? European Heart Journal, April 8, 2013 Review Article

14 Primary Prevention of Cardiovascular Disease with a Mediterranean Diet New England Journal of Medicine, April 8, 2013 Free full text

15 Testosterone and cardiovascular risk Internal and Emergency Medicine, March 21, 2013

16 Chlorthalidone Versus Hydrochlorothiazide for the Treatment of Hypertension in Older Adults A Population-Based Cohort Study Annals of Internal Medicine, March 19, 2013

17 Cell Therapy of Peripheral Arterial Disease Circulation Research, April 29, 2013

18 Cardiovascular events after clarithromycin use in lower respiratory tract infections: analysis of two prospective cohort studies British Medical Journal, April 10, 2013 Free full text

19 The endocrinology of exercise Internal and Emergency Medicine, March 27, 2013 Review Article
Exclusive Author Commentary

20 Coronary artery bypass graft surgery versus percutaneous coronary intervention in patients with three-vessel disease and left main coronary disease: 5-year follow-up of the randomised, clinical SYNTAX trial The Lancet, April 18, 2013

Indexed Journals in Internal Medicine: New England Journal of Medicine, The Lancet, Archives of Internal Medicine more

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Internal Medicine - Atherosclerosis/Lipids News & Articles

Articles

Clinical Pearls in Internal Medicine

Highlights in Internal Medicine

Vitamin D deficiency is associated with increased mortality in ICU patients

Coronary artery calcium increases cardiovascular risk in patients with T2DM and HTN

CAC scores add predictability to Framingham

Most Popular Internal Medicine Articles

Other Topics in Internal Medicine