Internal Medicine - Radiology/Diagnostics News & Articles

What makes MDLinx Internal Medicine different from all the other primary care literature reviews? Our team of medical editors read over 2,000 medical journals every day so you can stay current in less than 5 minutes! They sort, rank and summarize every article that will impact your daily practice. They even mark which articles are available in free full text, which are clinical or evidence-based, and which have MDLinx Exclusive Author Commentary from the people who actually performed the research.

Also on this page you’ll see bonus content from our physician editor, D. Scott Cunningham, MD, PhD, in the form of his top highlights you can’t miss, along with clinical pearls from The Smartest Internist, a quiz competition from the editors of MDLinx Internal Medicine in collaboration with the Cleveland Clinic Center for Continuing Education.

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Articles

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21 Effect of patient sex on white matter alterations in unilateral medial temporal lobe epilepsy with hippocampal sclerosis assessed by diffusion tensor imaging American Journal of Neuroradiology, May 22, 2013 Clinical Article

22 Ventricular pressure–volume loops obtained by 3D real-time echocardiography and mini pressure wire—a feasibility study Clinical Research in Cardiology, May 22, 2013 Clinical Article

23 The clinical and economic burden of newly diagnosed alzheimers disease in a medicare advantage population American Journal of Alzheimer's Disease and Other Dementias, May 22, 2013 Clinical Article

24 Time interval required for return to baseline of the background rhythm on electroencephalogram after recorded electrographic seizures Epilepsy Research, May 22, 2013 Clinical Article

25 Diagnosis and Treatment of Lymphedema Following Breast Cancer: A Population-based Study PM&R, May 22, 2013 Clinical Article

26 Yield of Routine Provocative Cardiac Testing Among Patients in an Emergency Department–Based Chest Pain Unit: Yield of Stress Testing in Emergency Department Observation Units JAMA Internal Medicine, May 21, 2013 Evidence Based Medicine Clinical Article

27 Defensive Medicine—Legally Necessary but Ethically Wrong? Inpatient Stress Testing for Chest Pain in Low-Risk Patients JAMA Internal Medicine, May 21, 2013 Review Article

28 Stage at diagnosis and colorectal cancer survival in six high-income countries: A population-based study of patients diagnosed during 2000-2007 Acta Oncologica, May 21, 2013 Clinical Article

29 Quantification of dry-needling and posture effects on myofascial trigger points using ultrasound shear-wave elastography Archives of Physical Medicine and Rehabilitation, May 21, 2013 Clinical Article

30 Next generation diagnostics of cystic fibrosis and CFTR-related disorders by targeted multiplex high-coverage resequencing of CFTR Journal of Medical Genetics, May 21, 2013 Review Article

31 Longitudinal comparison between MRI, MRS and histology-determined steatosis in NAFLD patients at two-time points in a randomized trial Hepatology, May 21, 2013 Clinical Article

32 Beyond Noise: Using Temporal ICA to Extract Meaningful Information from High-Frequency fMRI Signal Fluctuations during Rest Frontiers in Neurology, May 21, 2013 Review Article

33 Cost effectiveness of the NHS breast screening programme: life table model British Medical Journal, May 20, 2013 Evidence Based Medicine Clinical Article
Exclusive Author Commentary

34 Contrast enhanced CT-scan to diagnose intrahepatic cholangiocarcinoma in patients with cirrhosis Journal of Hepatology, May 20, 2013 Clinical Article

35 Increased Aortic Pulse Wave Velocity as Measured by Echocardiography Is Strongly Associated with Poor Prognosis in Patients with Heart Failure Journal of the American Society of Echocardiography, May 20, 2013 Clinical Article

36 The use of imaging to detect schistosomes and diagnose schistosomiasis Parasite Immunology, May 20, 2013 Review Article

37 Diagnostic accuracy of conventional or age adjusted D-dimer cut-off values in older patients with suspected venous thromboembolism: systematic review and meta-analysis British Medical Journal, May 20, 2013 Evidence Based Medicine Review Article Clinical Article

38 The Use of Sub-Mental Ultrasonography for Identifying Patients with Severe Obstructive Sleep Apnea PLOS ONE, May 17, 2013 Evidence Based Medicine Clinical Article

39 Movement disorders and the osmotic demyelination syndrome Parkinsonism & Related Disorders, May 17, 2013 Review Article

40 Neuromelanin MRI in a family with mitochondrial parkinsonism harboring a Y955C mutation in POLG1 Parkinsonism & Related Disorders, May 17, 2013 Review Article

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Clinical Pearls in Internal Medicine

Vitamin D deficiency is more common with non-Caucasian patients, and those with lower social support, no insurance, diabetes, lower activity levels, higher parathyroid hormone levels, and higher body mass indexes
Eating an early breakfast and dinner when taking PPIs can lower FSSG scores and improve GERD symptoms. (Factors leading to increased FSSG scores were female gender, inadequate sleep, lack of breakfast, antihypertensive agent non-users and dinner just before bedtime.)
No single method of contraception is contraindicated by age alone, but caution should be exercised with estrogen-containing preparations in obese women over 40

» Test your knowledge. Take the Smartest Doc challenge today!

Highlights in Internal Medicine

Vitamin D deficiency is associated with increased mortality in ICU patients

Among 130 patients requiring mechanical ventilation, 107 were vitamin D-deficient (< 20 ng/ml). Of the patients who did not survive, the length of survival was shorter in the vitamin D-deficient patients (15.3 vs. 24.2 days, respectively).

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Coronary artery calcium increases cardiovascular risk in patients with T2DM and HTN

Researchers at Tel-Aviv University have conducted a study to determine the value of coronary artery calcium (CAC) measurements in cardiovascular risk stratification in patients with T2DM and HTN. The study involved 423 patients enrolled in the International Nifedipine Study: Intervention as Goal for Hypertension Therapy. The patients had baseline CT scans for CAC measurement at baseline and were shown to be free of disease. Follow-up CT scans were performed at 3 and 15 years. Cardiovascular events (CVEs) occurred in 41 of 423 patients at 3 years and 111 of 268 patients at 15 years of follow-up. CVEs occurred in 15% and 52% (CAC+) and 7% and 32% (CAC-) of patients with T2DM at 3 and 15 years of follow-up, respectively. Compared to patients without T2DM and no CAC, the HRs for a CVE were 6.6 and 3.9 in T2DM patients with and without CAC, respectively.

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CAC scores add predictability to Framingham

Researchers at Erasmus University Medical Center in Rotterdam have evaluated 12 measures (N-terminal fragment of prohormone B-type natriuretic peptide levels, von Willebrand factor antigen levels, fibrinogen levels, chronic kidney disease, leukocyte count, C-reactive protein levels, homocysteine levels, uric acid levels, coronary artery calcium [CAC] scores, carotid intima–media thickness, peripheral arterial disease, and pulse wave velocity), in addition to Framingham risk scores for predicting coronary heart disease. Only the CAC was shown to add significantly to the Framingham risk score in predicting coronary heart disease.

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Most Popular Internal Medicine Articles

Last month's top read Top Articles of 2012

1 Bone mineral density testing: Is a T score enough to determine the screening interval? Cleveland Clinic Journal of Medicine, April 3, 2013 Free full text

2 Coronary artery bypass graft surgery versus percutaneous coronary intervention in patients with three-vessel disease and left main coronary disease: 5-year follow-up of the randomised, clinical SYNTAX trial The Lancet, April 18, 2013

3 Red flags to screen for malignancy in patients with low-back pain Cochrane Reviews, March 8, 2013

4 Iron deficiency in chronic heart failure: An international pooled analysis American Heart Journal, April 1, 2013

5 Infective Endocarditis New England Journal of Medicine, April 12, 2013

6 Postmortem cardiac 3T magnetic resonance imaging: Visualizing the sudden cardiac death? JACC - Journal of the American College of Cardiology, April 12, 2013

7 The Importance of 24-Hour Ambulatory Blood Pressure Monitoring in Patients at Risk of Cardiovascular Events High Blood Pressure & Cardiovascular Prevention, April 16, 2013

8 B-Type Natriuretic Peptide and Prognosis in Heart Failure Patients With Preserved and Reduced Ejection Fraction JACC - Journal of the American College of Cardiology, April 3, 2013 Free full text

9 The REMEDEE Trial A Randomized Comparison of a Combination Sirolimus-Eluting Endothelial Progenitor Cell Capture Stent With a Paclitaxel-Eluting Stent JACC Cardiovascular Interventions, April 17, 2013

10 Prevention and treatment of neurovascular in-stent stenoses: review of the concepts Expert Review of Cardiovascular Therapy , April 16, 2013 Review Article

11 Increased Odds of Interval Left-Sided Colorectal Cancer After Flexible Sigmoidoscopy Compared With Colonoscopy in Older Patients in the United States: A Population-Based Analysis of the SEER-Medicare Linked Database, 2001-2005 Mayo Clinic Proceedings, April 9, 2013 Evidence Based Medicine

12 Incidental Findings of the Lumbar Spine at MRI During Herniated Intervertebral Disk Disease Evaluation American Journal of Roentgenology, May 4, 2011

13 Association Between Left Ventricular Ejection Fraction Post-Cardiac Resynchronization Treatment and Subsequent Implantable Cardioverter Defibrillator Therapy for Sustained Ventricular Tachyarrhythmias Circulation: Arrhythmia and Electrophysiology, April 18, 2013

14 Outcomes of Screening Mammography by Frequency, Breast Density, and Postmenopausal Hormone Therapy Outcomes of Screening Mammography JAMA Internal Medicine, March 20, 2013

15 Diagnosis and management of carotid atherosclerosis British Medical Journal, March 22, 2013 Review Article
Exclusive Author Commentary

16 Pulmonary hypertension: diagnosis and management British Medical Journal, April 23, 2013 Review Article

17 Coronary artery calcium score prediction of all cause mortality and cardiovascular events in people with type 2 diabetes: systematic review and meta-analysis British Medical Journal, April 10, 2013 Free full text Evidence Based Medicine Review Article

18 Anti-ribosomal P protein IgG autoantibodies in patients with systemic lupus erythematosus: diagnostic performance and clinical profile BMC Medicine, April 9, 2013 Free full text

19 Long-term clinical follow-up of the multicenter, randomized study to test immunosuppressive therapy with oral prednisone for the prevention of restenosis after percutaneous coronary interventions: Cortisone plus BMS or DES veRsus BMS alone to EliminAte Restenosis (CEREA-DES) European Heart Journal, April 11, 2013

20 Metabolically healthy but obese, a matter of time? Findings from the prospective Pizarra study Journal of Clinical Endocrinology and Metabolism, April 5, 2013

Indexed Journals in Internal Medicine: New England Journal of Medicine, The Lancet, Archives of Internal Medicine more

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Internal Medicine - Radiology/Diagnostics News & Articles

Articles

Clinical Pearls in Internal Medicine

Highlights in Internal Medicine

Vitamin D deficiency is associated with increased mortality in ICU patients

Coronary artery calcium increases cardiovascular risk in patients with T2DM and HTN

CAC scores add predictability to Framingham

Most Popular Internal Medicine Articles

Other Topics in Internal Medicine