Internal Medicine - Vascular Medicine News & Articles

What makes MDLinx Internal Medicine different from all the other primary care literature reviews? Our team of medical editors read over 2,000 medical journals every day so you can stay current in less than 5 minutes! They sort, rank and summarize every article that will impact your daily practice. They even mark which articles are available in free full text, which are clinical or evidence-based, and which have MDLinx Exclusive Author Commentary from the people who actually performed the research.

Also on this page you’ll see bonus content from our physician editor, D. Scott Cunningham, MD, PhD, in the form of his top highlights you can’t miss, along with clinical pearls from The Smartest Internist, a quiz competition from the editors of MDLinx Internal Medicine in collaboration with the Cleveland Clinic Center for Continuing Education.

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Articles

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Ranked, sorted, and summarized by MDLinx editors from the latest literature

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161 Diabetes and bone health Maturitas, April 30, 2013 Clinical Article

162 Decremental Left Ventricular Deformation after Pulmonary Artery Band Training and Subsequent Repair in Ventriculoarterial Discordance Journal of the American Society of Echocardiography, April 30, 2013 Clinical Article

163 Association of Obesity with cardiovascular disease mortality in the PLCO trial Preventive Medicine, April 30, 2013 Review Article

164 Revisiting right atrial isolation rationale for atrial fibrillation: functional anatomy of interatrial connections Journal of Interventional Cardiac Electrophysiology , April 30, 2013 Clinical Article

165 Development and a Pilot Test of an Internet-Based Cardiovascular Risk Reduction Program for Korean Male Workers With Metabolic Syndrome Computers Informatics Nursing, April 30, 2013 Review Article

166 Combined non-invasive functional and anatomical diagnostic work-up in clinical practice: the magnetic resonance and computed tomography in suspected coronary artery disease (MARCC) study European Heart Journal, April 29, 2013 Clinical Article

167 Two-Year Outcomes for Patients With Severe Symptomatic Aortic Stenosis Treated With Transcatheter Aortic Valve Implantation The American Journal of Cardiology, April 29, 2013 Clinical Article

168 Cell Therapy of Peripheral Arterial Disease Circulation Research, April 29, 2013 Clinical Article

169 Visit-to-visit and 24-h blood pressure variability: association with endothelial and smooth muscle function in African Americans Journal of Human Hypertension, April 29, 2013 Clinical Article

170 Erectile dysfunction in the cardiovascular patient European Heart Journal, April 29, 2013 Clinical Article

171 Effects of watermelon supplementation on arterial stiffness and wave reflection amplitude in postmenopausal women Menopause, April 29, 2013 Clinical Article

172 Predictors of 30-day mortality and outcome in cases of myocardial infarction with cardiogenic shock treated by extracorporeal life support European Journal of Cardio-Thoracic Surgery, April 29, 2013 Clinical Article

173 A sequence variant associated with sortilin-1 (SORT1) on 1p13.3 is independently associated with abdominal aortic aneurysm Human Molecular Genetics, April 29, 2013 Review Article

174 Blood Pressure Variability: A Novel and Important Risk Factor Canadian Journal of Cardiology, April 29, 2013 Clinical Article

175 Oxidative stress in vascular disease and its pharmacological prevention Trends in Pharmacological Sciences, April 29, 2013 Clinical Article

176 Depressive disorder in the last phase of life in patients with cardiovascular disease, cancer, and COPD: data from a 20-year follow-up period in general practice British Journal of General Practice, April 29, 2013 Clinical Article

177 Serum albumin and short-term risk for mortality and cardiovascular disease among HIV-infected veterans AIDS, April 29, 2013 Clinical Article

178 Fractions of cardiovascular diseases and mental disorders attributable to psychosocial work factors in 31 countries in Europe International Archives of Occupational & Environmental Health, April 29, 2013 Clinical Article

179 Association between habitual physical activity and lower cardiovascular risk in premenopausal, perimenopausal, and postmenopausal women: a population-based study Menopause, April 26, 2013

180 Platelet REsponsiveness to CLOpidogrel treatment after Peripheral endovascular procedures - The PRECLOP study: Clinical Impact and Optimal Cut-off Value of High On Treatment Platelet Reactivity JACC - Journal of the American College of Cardiology, April 26, 2013 Clinical Article

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Clinical Pearls in Internal Medicine

Vitamin D deficiency is more common with non-Caucasian patients, and those with lower social support, no insurance, diabetes, lower activity levels, higher parathyroid hormone levels, and higher body mass indexes
Eating an early breakfast and dinner when taking PPIs can lower FSSG scores and improve GERD symptoms. (Factors leading to increased FSSG scores were female gender, inadequate sleep, lack of breakfast, antihypertensive agent non-users and dinner just before bedtime.)
No single method of contraception is contraindicated by age alone, but caution should be exercised with estrogen-containing preparations in obese women over 40

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Highlights in Internal Medicine

Vitamin D deficiency is associated with increased mortality in ICU patients

Among 130 patients requiring mechanical ventilation, 107 were vitamin D-deficient (< 20 ng/ml). Of the patients who did not survive, the length of survival was shorter in the vitamin D-deficient patients (15.3 vs. 24.2 days, respectively).

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Coronary artery calcium increases cardiovascular risk in patients with T2DM and HTN

Researchers at Tel-Aviv University have conducted a study to determine the value of coronary artery calcium (CAC) measurements in cardiovascular risk stratification in patients with T2DM and HTN. The study involved 423 patients enrolled in the International Nifedipine Study: Intervention as Goal for Hypertension Therapy. The patients had baseline CT scans for CAC measurement at baseline and were shown to be free of disease. Follow-up CT scans were performed at 3 and 15 years. Cardiovascular events (CVEs) occurred in 41 of 423 patients at 3 years and 111 of 268 patients at 15 years of follow-up. CVEs occurred in 15% and 52% (CAC+) and 7% and 32% (CAC-) of patients with T2DM at 3 and 15 years of follow-up, respectively. Compared to patients without T2DM and no CAC, the HRs for a CVE were 6.6 and 3.9 in T2DM patients with and without CAC, respectively.

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CAC scores add predictability to Framingham

Researchers at Erasmus University Medical Center in Rotterdam have evaluated 12 measures (N-terminal fragment of prohormone B-type natriuretic peptide levels, von Willebrand factor antigen levels, fibrinogen levels, chronic kidney disease, leukocyte count, C-reactive protein levels, homocysteine levels, uric acid levels, coronary artery calcium [CAC] scores, carotid intima–media thickness, peripheral arterial disease, and pulse wave velocity), in addition to Framingham risk scores for predicting coronary heart disease. Only the CAC was shown to add significantly to the Framingham risk score in predicting coronary heart disease.

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Most Popular Internal Medicine Articles

Last month's top read Top Articles of 2012

1 Effect of Disodium EDTA Chelation Regimen on Cardiovascular Events in Patients With Previous Myocardial Infarction: The TACT Randomized Trial JAMA, March 27, 2013 Evidence Based Medicine

2 Oral Anticoagulation and Implantation of Cardiac Rhythm Management Devices: Is Heparin a Bridge Too Far? The Hellenic Journal of Cardiology, April 16, 2013 Free full text

3 Biolimus-eluting biodegradable polymer-coated stent versus durable polymer-coated sirolimus-eluting stent in unselected patients receiving percutaneous coronary intervention (SORT OUT V): a randomised non-inferiority trial The Lancet, April 18, 2013

4 Dietary advice for reducing cardiovascular risk Cochrane Reviews, April 1, 2013

5 Comparison of Double Kissing Crush Versus Culotte Stenting for Unprotected Distal Left Main Bifurcation Lesions : Results From a Multicenter, Randomized, Prospective DKCRUSH-III Study JACC - Journal of the American College of Cardiology, April 2, 2013

6 Efficacy and safety of dabigatran etexilate and warfarin in real world patients with atrial fibrillation: A prospective nationwide cohort study JACC - Journal of the American College of Cardiology, April 15, 2013

7 Safety of aspirin desensitization in patients with reported aspirin allergy and cardiovascular disease Clinical Cardiology, September 26, 2012 Free full text

8 Practical use of dabigatran etexilate for stroke prevention in atrial fibrillation International Journal of Clinical Practice, April 9, 2013

9 Effect of Platelet Inhibition with Cangrelor during PCI on Ischemic Events New England Journal of Medicine, April 8, 2013

10 Effect of increased potassium intake on cardiovascular risk factors and disease: systematic review and meta-analyses British Medical Journal, April 8, 2013 Evidence Based Medicine

11 Duration of dual antiplatelet therapy after implantation of the first-generation and second-generation drug-eluting stents Coronary Artery Disease, April 10, 2013

12 Plasminogen activator inhibitor-1 5G/5G genotype is associated with early spontaneous recanalization of the infarct-related artery in patients presenting with acute ST-elevation myocardial infarction Coronary Artery Disease, April 10, 2013

13 Current State of Endovascular Treatment for Vasculogenic Erectile Dysfunction Current Cardiology Reports, April 8, 2013

14 Benefits and risks of long-term duration of dual antiplatelet therapy after drug-eluting stenting: A meta-analysis of randomized trials International Journal of Cardiology, April 17, 2013 Evidence Based Medicine Review Article

15 Insulin Resistance Is Associated With a Poor Response to Intravenous Thrombolysis in Acute Ischemic Stroke Diabetes Care, September 29, 2011 Free full text

16 Should all acutely ill medical patients be treated with antithrombotic drugs? Thrombosis and Haemostasis, April 23, 2013 Free full text Review Article

17 Prevalence, Correlation and Clinical Outcome of Intra-Procedural Stent Thrombosis in Patients Undergoing Primary Percutaneous Coronary Intervention for Acute Coronary Syndrome Journal of Interventional Cardiology, April 8, 2013

18 Improving the use of direct oral anticoagulants in atrial fibrillation European Journal of Internal Medicine , April 12, 2013

19 Pharmacologic Therapy for Primary Restless Legs Syndrome A Systematic Review and Meta-analysis Pharmacotherapy for Primary Restless Legs Syndrome JAMA Internal Medicine, April 10, 2013 Evidence Based Medicine Review Article

20 Coronary artery calcium score prediction of all cause mortality and cardiovascular events in people with type 2 diabetes: systematic review and meta-analysis British Medical Journal, April 10, 2013 Free full text Evidence Based Medicine Review Article

Indexed Journals in Internal Medicine: New England Journal of Medicine, The Lancet, Archives of Internal Medicine more

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Internal Medicine - Vascular Medicine News & Articles

Articles

Clinical Pearls in Internal Medicine

Highlights in Internal Medicine

Vitamin D deficiency is associated with increased mortality in ICU patients

Coronary artery calcium increases cardiovascular risk in patients with T2DM and HTN

CAC scores add predictability to Framingham

Most Popular Internal Medicine Articles

Other Topics in Internal Medicine