What makes MDLinx Internal Medicine different from all the other primary care literature reviews? Our team of medical editors read over 2,000 medical journals every day so you can stay current in less than 5 minutes! They sort, rank and summarize every article that will impact your daily practice. They even mark which articles are available in free full text, which are clinical or evidence-based, and which have MDLinx Exclusive Author Commentary from the people who actually performed the research.
Also on this page you’ll see bonus content from our physician editor, D. Scott Cunningham, MD, PhD, in the form of his top highlights you can’t miss, along with clinical pearls from The Smartest Internist, a quiz competition from the editors of MDLinx Internal Medicine in collaboration with the Cleveland Clinic Center for Continuing Education.
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121 Body temperature, blood infection parameters, and outcome of thrombolysis-treated ischemic stroke patients International Journal of Stroke, May 1, 2013 Clinical Article
122 Cardiovascular risk assessment of South Asian populations in religious and community settings: a qualitative study Family Practice, May 1, 2013 Review Article
123 Association between serum uric acid levels and cardiovascular risk among university workers from the State of Mexico: a nested case--control study Full Text BMC Public Health, May 1, 2013 Clinical Article
124 Can bioabsorbable scaffolds be used in calcified lesions Catheterization and Cardiovascular Interventions, May 1, 2013
125 Predictors of shuttle walking test performance in patients with cardiovascular disease Physiotherapy, May 1, 2013 Clinical Article
126 Higher coated-platelet levels are associated with chronic hypertension in patients with transient ischemic attack Platelets, May 1, 2013 Clinical Article
127 Sociodemographic Determinants in Preventive Tests for Cardiovascular Diseases in a Representative Sample of the Adult Greek Population High Blood Pressure & Cardiovascular Prevention, May 1, 2013 Review Article
128
Using Impedance Cardiography to Detect Asymptomatic Cardiovascular Disease in Prehypertensive Adults with Risk Factors
High Blood Pressure & Cardiovascular Prevention, May 1, 2013
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Exclusive Author Commentary
129 Randomized trial comparing the efficacy between different types of paclitaxel-eluting stents: The comparison of Efficacy between COroflex PLEASe ANd Taxus stent (ECO-PLEASANT) randomized controlled trial American Heart Journal, April 30, 2013 Clinical Article
130 Contrast-induced acute kidney injury and clinical outcomes after intra-arterial and intravenous contrast administration: Risk comparison adjusted for patient characteristics by design American Heart Journal, April 30, 2013 Clinical Article
131 Rationale and design of the LEADERS FREE trial: A randomized double-blind comparison of the BioFreedom drug-coated stent vs the Gazelle bare metal stent in patients at high bleeding risk using a short (1 month) course of dual antiplatelet therapy American Heart Journal, April 30, 2013 Clinical Article
132 Comparative effectiveness of coronary artery bypass grafting and percutaneous coronary intervention for multivessel coronary disease in a community-based population with chronic kidney disease American Heart Journal, April 30, 2013 Clinical Article
133 Sensitive troponin assays and N-terminal pro-B-type natriuretic peptide in acute coronary syndrome: Prediction of significant coronary lesions and long-term prognosis American Heart Journal, April 30, 2013 Clinical Article
134 Gender and racial disparities in adherence to statin therapy: A meta-analysis American Heart Journal, April 30, 2013 Evidence Based Medicine Review Article
135 High mortality risks after major lower extremity amputation in Medicare patients with peripheral artery disease American Heart Journal, April 30, 2013 Clinical Article
136 Saphenous vein graft failure and clinical outcomes: Toward a surrogate end point in patients following coronary artery bypass surgery? American Heart Journal, April 30, 2013 Clinical Article
137 The outcome of intra-aortic balloon pump support in acute myocardial infarction complicated by cardiogenic shock according to the type of revascularization: A comprehensive meta-analysis American Heart Journal, April 30, 2013 Evidence Based Medicine Review Article
138 Parathyroid hormone and cardiovascular disease events: A systematic review and meta-analysis of prospective studies American Heart Journal, April 30, 2013 Evidence Based Medicine Review Article
139 Simvastatin impairs exercise training adaptations JACC - Journal of the American College of Cardiology, April 30, 2013 Clinical Article
140 Positron Emission Tomography/Computed Tomography for Diagnosis of Prosthetic Valve Endocarditis: Increased Valvular 18F-Fluorodeoxyglucose Uptake as a Novel Major Criterion JACC - Journal of the American College of Cardiology, April 30, 2013 Clinical Article
Among 130 patients requiring mechanical ventilation, 107 were vitamin D-deficient (< 20 ng/ml). Of the patients who did not survive, the length of survival was shorter in the vitamin D-deficient patients (15.3 vs. 24.2 days, respectively).
Read the article summaryResearchers at Tel-Aviv University have conducted a study to determine the value of coronary artery calcium (CAC) measurements in cardiovascular risk stratification in patients with T2DM and HTN. The study involved 423 patients enrolled in the International Nifedipine Study: Intervention as Goal for Hypertension Therapy. The patients had baseline CT scans for CAC measurement at baseline and were shown to be free of disease. Follow-up CT scans were performed at 3 and 15 years. Cardiovascular events (CVEs) occurred in 41 of 423 patients at 3 years and 111 of 268 patients at 15 years of follow-up. CVEs occurred in 15% and 52% (CAC+) and 7% and 32% (CAC-) of patients with T2DM at 3 and 15 years of follow-up, respectively. Compared to patients without T2DM and no CAC, the HRs for a CVE were 6.6 and 3.9 in T2DM patients with and without CAC, respectively.
Read the article summaryResearchers at Erasmus University Medical Center in Rotterdam have evaluated 12 measures (N-terminal fragment of prohormone B-type natriuretic peptide levels, von Willebrand factor antigen levels, fibrinogen levels, chronic kidney disease, leukocyte count, C-reactive protein levels, homocysteine levels, uric acid levels, coronary artery calcium [CAC] scores, carotid intima–media thickness, peripheral arterial disease, and pulse wave velocity), in addition to Framingham risk scores for predicting coronary heart disease. Only the CAC was shown to add significantly to the Framingham risk score in predicting coronary heart disease.
Read the article summary1 Effect of Disodium EDTA Chelation Regimen on Cardiovascular Events in Patients With Previous Myocardial Infarction: The TACT Randomized Trial JAMA, March 27, 2013 Evidence Based Medicine
2 Oral Anticoagulation and Implantation of Cardiac Rhythm Management Devices: Is Heparin a Bridge Too Far? The Hellenic Journal of Cardiology, April 16, 2013 Free full text
3 Biolimus-eluting biodegradable polymer-coated stent versus durable polymer-coated sirolimus-eluting stent in unselected patients receiving percutaneous coronary intervention (SORT OUT V): a randomised non-inferiority trial The Lancet, April 18, 2013
4 Dietary advice for reducing cardiovascular risk Cochrane Reviews, April 1, 2013
5 Comparison of Double Kissing Crush Versus Culotte Stenting for Unprotected Distal Left Main Bifurcation Lesions : Results From a Multicenter, Randomized, Prospective DKCRUSH-III Study JACC - Journal of the American College of Cardiology, April 2, 2013
6 Efficacy and safety of dabigatran etexilate and warfarin in real world patients with atrial fibrillation: A prospective nationwide cohort study JACC - Journal of the American College of Cardiology, April 15, 2013
7 Safety of aspirin desensitization in patients with reported aspirin allergy and cardiovascular disease Clinical Cardiology, September 26, 2012 Free full text
8 Practical use of dabigatran etexilate for stroke prevention in atrial fibrillation International Journal of Clinical Practice, April 9, 2013
9 Effect of Platelet Inhibition with Cangrelor during PCI on Ischemic Events New England Journal of Medicine, April 8, 2013
10 Effect of increased potassium intake on cardiovascular risk factors and disease: systematic review and meta-analyses British Medical Journal, April 8, 2013 Evidence Based Medicine
11 Duration of dual antiplatelet therapy after implantation of the first-generation and second-generation drug-eluting stents Coronary Artery Disease, April 10, 2013
12 Plasminogen activator inhibitor-1 5G/5G genotype is associated with early spontaneous recanalization of the infarct-related artery in patients presenting with acute ST-elevation myocardial infarction Coronary Artery Disease, April 10, 2013
13 Current State of Endovascular Treatment for Vasculogenic Erectile Dysfunction Current Cardiology Reports, April 8, 2013
14 Benefits and risks of long-term duration of dual antiplatelet therapy after drug-eluting stenting: A meta-analysis of randomized trials International Journal of Cardiology, April 17, 2013 Evidence Based Medicine Review Article
15 Insulin Resistance Is Associated With a Poor Response to Intravenous Thrombolysis in Acute Ischemic Stroke Diabetes Care, September 29, 2011 Free full text
16 Should all acutely ill medical patients be treated with antithrombotic drugs? Thrombosis and Haemostasis, April 23, 2013 Free full text Review Article
17 Prevalence, Correlation and Clinical Outcome of Intra-Procedural Stent Thrombosis in Patients Undergoing Primary Percutaneous Coronary Intervention for Acute Coronary Syndrome Journal of Interventional Cardiology, April 8, 2013
18 Improving the use of direct oral anticoagulants in atrial fibrillation European Journal of Internal Medicine , April 12, 2013
19 Pharmacologic Therapy for Primary Restless Legs Syndrome A Systematic Review and Meta-analysis Pharmacotherapy for Primary Restless Legs Syndrome JAMA Internal Medicine, April 10, 2013 Evidence Based Medicine Review Article
20 Coronary artery calcium score prediction of all cause mortality and cardiovascular events in people with type 2 diabetes: systematic review and meta-analysis British Medical Journal, April 10, 2013 Free full text Evidence Based Medicine Review Article
Indexed Journals in Internal Medicine: New England Journal of Medicine, The Lancet, Archives of Internal Medicine more
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