What makes MDLinx Internal Medicine different from all the other primary care literature reviews? Our team of medical editors read over 2,000 medical journals every day so you can stay current in less than 5 minutes! They sort, rank and summarize every article that will impact your daily practice. They even mark which articles are available in free full text, which are clinical or evidence-based, and which have MDLinx Exclusive Author Commentary from the people who actually performed the research.
Also on this page you’ll see bonus content from our physician editor, D. Scott Cunningham, MD, PhD, in the form of his top highlights you can’t miss, along with clinical pearls from The Smartest Internist, a quiz competition from the editors of MDLinx Internal Medicine in collaboration with the Cleveland Clinic Center for Continuing Education.
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121 Methods of Prescribing Relative Exercise Intensity: Physiological and Practical Considerations Sports Medicine, April 26, 2013 Review Article
122 Exercise-induced bronchoconstriction Annals of Allergy, Asthma, and Immunology, April 26, 2013 Review Article
123 The Correlation Between Dose of Folinic Acid and Neurotoxicity in Children and Adolescents Treated for Osteosarcoma With High-dose Methotrexate (HDMTX): A Neuropsychological and Psychosocial Study Journal of Pediatric Hematology/Oncology, April 26, 2013 Clinical Article
124 On the relationship between pain intensity and postural sway in patients with non-specific neck pain Journal of Back and Musculoskeletal Rehabilitation, April 26, 2013 Evidence Based Medicine
125 A Disintegrin And Metalloproteinase 12 produced by tumour cells accelerates osteosarcoma tumour progression and associated osteolysis European Journal of Cancer, April 26, 2013 Clinical Article
126 Outpatient parenteral antibiotic therapy: Principles and practice European Journal of Internal Medicine , April 25, 2013 Clinical Article
127 Comprehensive Approach to Lower Blood Pressure (CALM-BP): a randomized controlled trial of a multifactorial lifestyle interventionOpen Journal of Human Hypertension, April 25, 2013 Clinical Article
128 Home-based versus hospital-based high-intensity interval training in cardiac rehabilitation: a randomized study European Journal of Preventive Cardiology, April 25, 2013 Clinical Article
129 Optimizing Prediction of Back Pain Outcomes Pain, April 25, 2013 Clinical Article
130 Assessing the Validity of the Dynamic Gait Index in a Balance Disorders Clinic: An Application of Rasch Analysis Physical Therapy, April 25, 2013 Review Article
131 Osteoporosis treatment European Journal of Internal Medicine , April 24, 2013 Clinical Article
132 The relationship between longitudinal serum leptin measures and measures of magnetic resonance imaging-assessed knee joint damage in a population of mid-life women Annals of Rheumatic Diseases, April 24, 2013 Clinical Article
133 Measuring Evidence-Based Practice in Physical Therapy: Translation, Adaptation, Further Development, Validation, and Reliability Test of a Questionnaire Physical Therapy, April 24, 2013 Evidence Based Medicine
134 A Physical Therapist-Established Intensive Care Unit Early Mobilization Program: A Quality Improvement Project for Critical Care at the University of California San Francisco Medical Center Physical Therapy, April 24, 2013 Review Article
135 Changes in Dynamic Plantar Pressure During Loaded Gait Physical Therapy, April 24, 2013 Clinical Article
136 Effectiveness of participatory training for prevention of musculoskeletal disorders: a randomized controlled trial International Archives of Occupational & Environmental Health, April 24, 2013 Clinical Article
137 Prospective observational study of physical functioning, physical activity and time outdoors and the risk of hip fracture: A population based cohort study of 158 057 older adults in the 45 and Up Study Journal of Bone and Mineral Research, April 23, 2013 Clinical Article
138 (18F)Fluoro-deoxy-D-glucose uptake of knee joints in the aspect of age-related osteoarthritis: a case-control study Full Text BMC Musculoskeletal Disorders, April 23, 2013 Clinical Article
139 Incidence of Musculoskeletal and Neoplastic Diseases in Patients on Statin Therapy: Results of a Retrospective Cohort Analysis The American Journal of the Medical Sciences, April 23, 2013 Clinical Article
140 Systematic Review of Randomized Controlled Trials of Clinical Prediction Rules for Physical Therapy in Low Back Pain Spine, April 23, 2013 Review Article Clinical Article
Among 130 patients requiring mechanical ventilation, 107 were vitamin D-deficient (< 20 ng/ml). Of the patients who did not survive, the length of survival was shorter in the vitamin D-deficient patients (15.3 vs. 24.2 days, respectively).
Read the article summaryResearchers at Tel-Aviv University have conducted a study to determine the value of coronary artery calcium (CAC) measurements in cardiovascular risk stratification in patients with T2DM and HTN. The study involved 423 patients enrolled in the International Nifedipine Study: Intervention as Goal for Hypertension Therapy. The patients had baseline CT scans for CAC measurement at baseline and were shown to be free of disease. Follow-up CT scans were performed at 3 and 15 years. Cardiovascular events (CVEs) occurred in 41 of 423 patients at 3 years and 111 of 268 patients at 15 years of follow-up. CVEs occurred in 15% and 52% (CAC+) and 7% and 32% (CAC-) of patients with T2DM at 3 and 15 years of follow-up, respectively. Compared to patients without T2DM and no CAC, the HRs for a CVE were 6.6 and 3.9 in T2DM patients with and without CAC, respectively.
Read the article summaryResearchers at Erasmus University Medical Center in Rotterdam have evaluated 12 measures (N-terminal fragment of prohormone B-type natriuretic peptide levels, von Willebrand factor antigen levels, fibrinogen levels, chronic kidney disease, leukocyte count, C-reactive protein levels, homocysteine levels, uric acid levels, coronary artery calcium [CAC] scores, carotid intima–media thickness, peripheral arterial disease, and pulse wave velocity), in addition to Framingham risk scores for predicting coronary heart disease. Only the CAC was shown to add significantly to the Framingham risk score in predicting coronary heart disease.
Read the article summary1 The pathogenesis of osteoarthritis involves bone, cartilage and synovial inflammation: may estrogen be a magic bullet? Menopause International, April 11, 2013
2 Does Vigorous Physical Activity Provide Additional Benefits Beyond Those of Moderate? Medicine and Science in Sports and Exercise, April 16, 2013 Evidence Based Medicine
3 Surgery versus Physical Therapy for a Meniscal Tear and Osteoarthritis New England Journal of Medicine, March 27, 2013
4 Natural course of acute neck and low back pain in the general population: The HUNT study Pain, April 8, 2013
5 Walking Versus Running for Hypertension, Cholesterol, and Diabetes Mellitus Risk Reduction Arteriosclerosis, Thrombosis, and Vascular Biology, April 17, 2013
6 Role of exercise in the prevention of cardiovascular disease: results, mechanisms, and new perspectives European Heart Journal, April 11, 2013
7 Effects of vitamin D supplementation on body fat accumulation, inflammation, and metabolic risk factors in obese adults with low vitamin D levels -- Results from a randomized trial European Journal of Internal Medicine , April 11, 2013
8 The impact of coffee on health Maturitas, February 26, 2013
9 Effect of physical activity on heart rate variability and carotid intima-media thickness in older people Internal and Emergency Medicine, March 27, 2013
10 Association between habitual physical activity and lower cardiovascular risk in premenopausal, perimenopausal, and postmenopausal women: a population-based study Menopause, April 26, 2013
11 Steps to a better Belfast: physical activity assessment and promotion in primary care British Journal of Sports Medicine, March 27, 2013 Evidence Based Medicine
12 Achilles and Patellar Tendinopathy Loading Programmes Sports Medicine, April 5, 2013 Review Article
13 Red flags to screen for malignancy in patients with low-back pain Cochrane Reviews, March 8, 2013
14 Muscle Damaging Exercise Increases Heat Strain during Subsequent Exercise Heat Stress Medicine and Science in Sports and Exercise, April 16, 2013 Evidence Based Medicine
15 Direct access and patient/client self-referral to physiotherapy: a review of contemporary practice within the European Union Physiotherapy, April 5, 2013 Review Article
16 A prospective randomized controlled trial comparing occupational therapy with home-based exercises in conservative treatment of rotator cuff tears Journal of Shoulder and Elbow Surgery, March 29, 2013 Evidence Based Medicine
17 Pain experiences and self-management strategies among middle-aged and older adults with arthritis Journal of Clinical Nursing, April 2, 2013
18 Preoperative Vitamin D Status of Adults Undergoing Surgical Spinal Fusion Spine, March 18, 2013
19 Prevalence of Vitamin D Deficiency in Patients with Lumbar Spinal Stenosis and Its Relationship with Pain Pain Physician, April 5, 2013 Free full text
20 Prognostic factors for patellofemoral pain: a multicentre observational analysis British Journal of Sports Medicine, March 13, 2013
Indexed Journals in Internal Medicine: New England Journal of Medicine, The Lancet, Archives of Internal Medicine more
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