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Internal Medicine - Endocrinology News & Articles

What makes MDLinx Internal Medicine different from all the other primary care literature reviews? Our team of medical editors read over 2,000 medical journals every day so you can stay current in less than 5 minutes! They sort, rank and summarize every article that will impact your daily practice. They even mark which articles are available in free full text, which are clinical or evidence-based, and which have MDLinx Exclusive Author Commentary from the people who actually performed the research.

Also on this page you’ll see bonus content from our physician editor, D. Scott Cunningham, MD, PhD, in the form of his top highlights you can’t miss, along with clinical pearls from The Smartest Internist, a quiz competition from the editors of MDLinx Internal Medicine in collaboration with the Cleveland Clinic Center for Continuing Education.

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Articles

Latest (17) Full Text Articles (1217) Focus on Substance Abuse
Ranked, sorted, and summarized by MDLinx editors from the latest literature
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81 Study Design and Rationale of a Dose-Ranging Trial of LX4211, a Dual Inhibitor of SGLT1 and SGLT2, in Type 2 Diabetes Inadequately Controlled on Metformin Monotherapy Full Text Clinical Cardiology, May 13, 2013    Clinical Article

82 Epidemiology of blindness attributable to diabetes in Scotland: change over 20 years in a defined population Diabetic Medicine, May 13, 2013    Review Article

83 Pre-diabetes in adults 45 years and over in Ireland: the Survey of Lifestyle, Attitudes and Nutrition in Ireland 2007 Diabetic Medicine, May 13, 2013    Clinical Article

84 Developing long-acting growth hormone formulations Clinical Endocrinology, May 13, 2013    Review Article

85 Cytoreductive surgery combined with hyperthermic intrapleural chemotherapy to treat thymoma or thymic carcinoma with pleural dissemination Full Text OncoTargets and Therapy, May 13, 2013    Clinical Article

86 Advanced medullary thyroid cancer: pathophysiology and management Full Text Cancer Management and Research, May 13, 2013    Clinical Article

87 Efficacy of individualized homeopathic treatment and fluoxetine for moderate to severe depression in peri- and postmenopausal women (HOMDEP-MENOP): study protocol for a randomized, double-dummy, double-blind, placebo-controlled trial Full Text Trials, May 10, 2013    Clinical Article

88 Characteristics Associated With Maintenance of Mean A1C <6.5% in People With Dysglycemia in the ORIGIN Trial Diabetes Care, May 10, 2013    Clinical Article

89 Paraoxonase is reduced in patients with growth hormone deficiency: A novel risk factor for atherosclerosis Journal of Research in Medical Sciences, May 10, 2013    Evidence Based Medicine    Clinical Article

90 Estimating the Population Prevalence of Diagnosed and Undiagnosed Diabetes Diabetes Care, May 10, 2013    Clinical Article

91 Fat Distribution and Glucose Intolerance Among Greenland Inuit Diabetes Care, May 10, 2013    Review Article

92 Are diabetes risk scores useful for the prediction of cardiovascular diseases? Assessment of seven diabetes risk scores in the KORA S4/F4 cohort study Journal of Diabetes and its Complications, May 10, 2013    Clinical Article

93 The influence of subclinical cardiovascular disease and related risk factors on cognition in type 2 diabetes mellitus: The DHS-Mind study Journal of Diabetes and its Complications, May 10, 2013    Clinical Article

94 [123I]Iodometomidate Imaging in Adrenocortical Carcinoma Journal of Clinical Endocrinology and Metabolism, May 10, 2013    Clinical Article

95 PTH (1–84) Replacement Therapy in Hypoparathyroidism: a Randomized Controlled Trial on Pharmacokinetic and Dynamic effects following 6 months of treatment Journal of Bone and Mineral Research, May 10, 2013    Clinical Article

96 Evaluation of two single-factor models of metabolic syndrome: a confirmatory factor analysis for an adult population in Beijing Full Text Lipids in Health and Disease, May 10, 2013    Review Article

97 Metabolic Syndrome and Hemoglobin Levels in Elderly Adults: The Invecchiare in Chianti Study Journal of the American Geriatrics Society, May 10, 2013    Review Article

98 Thyroid Status and 6-Year Mortality in Elderly People Living in a Mildly Iodine-Deficient Area: The Aging in the Chianti Area Study Journal of the American Geriatrics Society, May 10, 2013    Review Article
Exclusive Author Commentary

99 Changes in serum aldosterone are associated with changes in obesity-related factors in normotensive overweight and obese young adults Hypertension Research, May 10, 2013    Clinical Article

100 Diagnostic accuracy of HbA1c in diabetes between Eastern and Western European Journal of Clinical Investigation, May 10, 2013    Review Article

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Clinical Pearls in Internal Medicine

Highlights in Internal Medicine

Vitamin D deficiency is associated with increased mortality in ICU patients

Among 130 patients requiring mechanical ventilation, 107 were vitamin D-deficient (< 20 ng/ml). Of the patients who did not survive, the length of survival was shorter in the vitamin D-deficient patients (15.3 vs. 24.2 days, respectively).

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Coronary artery calcium increases cardiovascular risk in patients with T2DM and HTN

Researchers at Tel-Aviv University have conducted a study to determine the value of coronary artery calcium (CAC) measurements in cardiovascular risk stratification in patients with T2DM and HTN. The study involved 423 patients enrolled in the International Nifedipine Study: Intervention as Goal for Hypertension Therapy. The patients had baseline CT scans for CAC measurement at baseline and were shown to be free of disease. Follow-up CT scans were performed at 3 and 15 years. Cardiovascular events (CVEs) occurred in 41 of 423 patients at 3 years and 111 of 268 patients at 15 years of follow-up. CVEs occurred in 15% and 52% (CAC+) and 7% and 32% (CAC-) of patients with T2DM at 3 and 15 years of follow-up, respectively. Compared to patients without T2DM and no CAC, the HRs for a CVE were 6.6 and 3.9 in T2DM patients with and without CAC, respectively.

Read the article summary

CAC scores add predictability to Framingham

Researchers at Erasmus University Medical Center in Rotterdam have evaluated 12 measures (N-terminal fragment of prohormone B-type natriuretic peptide levels, von Willebrand factor antigen levels, fibrinogen levels, chronic kidney disease, leukocyte count, C-reactive protein levels, homocysteine levels, uric acid levels, coronary artery calcium [CAC] scores, carotid intima–media thickness, peripheral arterial disease, and pulse wave velocity), in addition to Framingham risk scores for predicting coronary heart disease. Only the CAC was shown to add significantly to the Framingham risk score in predicting coronary heart disease.

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Most Popular Internal Medicine Articles

Last month's top read Top Articles of 2012

1 Walking Versus Running for Hypertension, Cholesterol, and Diabetes Mellitus Risk Reduction Arteriosclerosis, Thrombosis, and Vascular Biology, April 17, 2013

2 Canagliflozin Compared With Sitagliptin for Patients With Type 2 Diabetes Who Do Not Have Adequate Glycemic Control With Metformin Plus Sulfonylurea: A 52-week randomized trial Diabetes Care, April 9, 2013

3 Vitamin D Levels for Preventing Acute Coronary Syndrome and Mortality: Evidence of a Non-Linear Association Journal of Clinical Endocrinology and Metabolism, March 27, 2013
Exclusive Author Commentary

4 Treatment of Iron-deficiency Anemia in Patients with Subclinical Hypothyroidism American Journal of Medicine, April 18, 2013

5 Testosterone and cardiovascular risk Internal and Emergency Medicine, March 21, 2013

6 Effects of vitamin D supplementation on body fat accumulation, inflammation, and metabolic risk factors in obese adults with low vitamin D levels -- Results from a randomized trial European Journal of Internal Medicine , April 11, 2013

7 The endocrinology of exercise Internal and Emergency Medicine, March 27, 2013    Review Article
Exclusive Author Commentary

8 The Importance of 24-Hour Ambulatory Blood Pressure Monitoring in Patients at Risk of Cardiovascular Events High Blood Pressure & Cardiovascular Prevention, April 16, 2013

9 Predictors of diabetic nephropathy Central European Journal of Medicine, April 23, 2013

10 Masked Hypertension in Diabetes Mellitus-Treatment Implications for Clinical Practice Hypertension, April 19, 2013

11 Antihypertensive therapy: nocturnal dippers and nondippers. Do we treat them differently? Vascular Health and Risk Management, March 26, 2013    Free full text

12 Detecting and controlling diabetic nephropathy: What do we know? Cleveland Clinic Journal of Medicine, April 3, 2013    Free full text

13 Bariatric surgery for type 2 diabetes The Lancet, March 20, 2013

14 Sitagliptin pretreatment in diabetes patients presenting with acute coronary syndrome: results from the Acute Coronary Syndrome Israeli Survey (ACSIS) Cardiovascular Diabetology, March 29, 2013    Free full text

15 Effect of Morbid Obesity on In-Hospital Mortality and Coronary Revascularization Outcomes After Acute Myocardial Infarction in the United States The American Journal of Cardiology, April 5, 2013

16 Teriparatide for Idiopathic Osteoporosis in Premenopausal Women: A Pilot Study Journal of Clinical Endocrinology and Metabolism, April 5, 2013

17 Comparison of Diabetic Ketoacidosis in Patients With Type-1 and Type-2 Diabetes Mellitus The American Journal of the Medical Sciences, April 1, 2013

18 The impact of coffee on health Maturitas, February 26, 2013

19 Mortality and Morbidity During and After Antihypertensive and Lipid-Lowering Treatment to Prevent Heart Attack Trial Hypertension, April 19, 2013

20 Vildagliptin in addition to metformin improves retinal blood flow and erythrocyte deformability in patients with type 2 diabetes mellitus -- results from an exploratory study Cardiovascular Diabetology, April 12, 2013    Free full text

Indexed Journals in Internal Medicine: New England Journal of Medicine, The Lancet, Archives of Internal Medicinemore

Other Topics in Internal Medicine

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