Internal Medicine - Endocrinology News & Articles

What makes MDLinx Internal Medicine different from all the other primary care literature reviews? Our team of medical editors read over 2,000 medical journals every day so you can stay current in less than 5 minutes! They sort, rank and summarize every article that will impact your daily practice. They even mark which articles are available in free full text, which are clinical or evidence-based, and which have MDLinx Exclusive Author Commentary from the people who actually performed the research.

Also on this page you’ll see bonus content from our physician editor, D. Scott Cunningham, MD, PhD, in the form of his top highlights you can’t miss, along with clinical pearls from The Smartest Internist, a quiz competition from the editors of MDLinx Internal Medicine in collaboration with the Cleveland Clinic Center for Continuing Education.

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Articles

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Ranked, sorted, and summarized by MDLinx editors from the latest literature

Topics:

181 Adrenal Venous Sampling for Primary Hyperaldosteronism in Patients with Concurrent Chronic Kidney Disease Journal of Vascular and Interventional Radiology, May 10, 2013 Clinical Article

182 Regional and Neighborhood Disparities in the Odds of Type 2 Diabetes: Results From 5 Population-Based Studies in Germany (DIAB-CORE Consortium) American Journal of Epidemiology, May 9, 2013 Clinical Article

183 Sustained Activation of mTORC1 in Skeletal Muscle Inhibits Constitutive and Starvation-Induced Autophagy and Causes a Severe, Late-Onset Myopathy Cell Metabolism, May 9, 2013 Review Article

184 Safety, pharmacokinetics and pharmacodynamics of remogliflozin etabonate, a novel SGLT2 inhibitor, and metformin when co-administered in subjects with type 2 diabetes mellitus Full Text BMC Pharmacology & Toxicology, May 9, 2013 Clinical Article

185 Apples and oranges: a comparison of costing methods for obesity Obesity Reviews, May 9, 2013 Review Article

186 Diabetes is not an independent risk factor for hepatocellular carcinoma Diabetes/Metabolism Research and Reviews, May 9, 2013 Review Article

187 Vibration perception threshold for sight-threatening retinopathy screening in type 2 diabetic outpatients Diabetes/Metabolism Research and Reviews, May 9, 2013 Review Article

188 Clinical characteristics and insulin-independency of new-onset Korean type 2 diabetics presenting with diabetic ketoacidosis Diabetes/Metabolism Research and Reviews, May 9, 2013 Review Article

189 Ketoacidosis as the initial clinical condition in nine patients with acromegaly: A review of 860 cases at a single institute European Journal of Endocrinology, May 9, 2013 Review Article

190 Transglucosidase improves the gut microbiota profile of type 2 diabetes mellitus patients: a randomized double-blind, placebo-controlled study Full Text BMC Gastroenterology, May 9, 2013

191 A Novel Bioassay for Anti-Tsh Receptor Autoantibodies Detects Both Thyroid-Blocking and Stimulating Activity Clinical and Experimental Immunology, May 9, 2013 Clinical Article

192 Diabetes is a strong predictor of mortality during tuberculosis treatment: a prospective cohort study among tuberculosis patients from Mwanza, Tanzania Tropical Medicine & International Health, May 9, 2013 Clinical Article

193 Latest insights into the risk of cancer in diabetes Journal of Diabetes Investigation, May 9, 2013 Review Article

194 Diabetes management and glycemic control in youth with type 1 diabetes: test of a predictive model Journal of Behavioral Medicine, May 9, 2013 Clinical Article

195 Adapting the SLIM diabetes prevention intervention to a Dutch real-life setting: joint decision making by science and practice Full Text BMC Public Health, May 9, 2013 Review Article

196 Cushing's syndrome after intralesional triamcinolone acetonide: A systematic review of the literature and multinational survey Burns, May 9, 2013 Evidence Based Medicine Review Article

197 Single-Nucleotide Polymorphisms in Adiponectin, AdipoR1, and AdipoR2 Genes: Insulin Resistance and Type 2 Diabetes Mellitus Candidate Genes American Journal of Therapeutics, May 9, 2013 Review Article

198 The 2012 CDA-CIHR INMD Young Investigator Award Lecture: Dysfunction of Adipose Tissues and the Mechanisms of Ectopic Fat Deposition in Type 2 Diabetes Canadian Journal of Diabetes, May 9, 2013 Review Article

199 Hemodialysis in patients requiring 131I treatment for thyroid carcinoma The International Journal of Artificial Organs, May 9, 2013

200 Heart failure in hospitalized patients with diabetic foot ulcers: clinical characteristics and its relationship to prognosis Journal of Diabetes, May 9, 2013 Review Article

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Clinical Pearls in Internal Medicine

Vitamin D deficiency is more common with non-Caucasian patients, and those with lower social support, no insurance, diabetes, lower activity levels, higher parathyroid hormone levels, and higher body mass indexes
Eating an early breakfast and dinner when taking PPIs can lower FSSG scores and improve GERD symptoms. (Factors leading to increased FSSG scores were female gender, inadequate sleep, lack of breakfast, antihypertensive agent non-users and dinner just before bedtime.)
No single method of contraception is contraindicated by age alone, but caution should be exercised with estrogen-containing preparations in obese women over 40

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Highlights in Internal Medicine

Vitamin D deficiency is associated with increased mortality in ICU patients

Among 130 patients requiring mechanical ventilation, 107 were vitamin D-deficient (< 20 ng/ml). Of the patients who did not survive, the length of survival was shorter in the vitamin D-deficient patients (15.3 vs. 24.2 days, respectively).

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Coronary artery calcium increases cardiovascular risk in patients with T2DM and HTN

Researchers at Tel-Aviv University have conducted a study to determine the value of coronary artery calcium (CAC) measurements in cardiovascular risk stratification in patients with T2DM and HTN. The study involved 423 patients enrolled in the International Nifedipine Study: Intervention as Goal for Hypertension Therapy. The patients had baseline CT scans for CAC measurement at baseline and were shown to be free of disease. Follow-up CT scans were performed at 3 and 15 years. Cardiovascular events (CVEs) occurred in 41 of 423 patients at 3 years and 111 of 268 patients at 15 years of follow-up. CVEs occurred in 15% and 52% (CAC+) and 7% and 32% (CAC-) of patients with T2DM at 3 and 15 years of follow-up, respectively. Compared to patients without T2DM and no CAC, the HRs for a CVE were 6.6 and 3.9 in T2DM patients with and without CAC, respectively.

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CAC scores add predictability to Framingham

Researchers at Erasmus University Medical Center in Rotterdam have evaluated 12 measures (N-terminal fragment of prohormone B-type natriuretic peptide levels, von Willebrand factor antigen levels, fibrinogen levels, chronic kidney disease, leukocyte count, C-reactive protein levels, homocysteine levels, uric acid levels, coronary artery calcium [CAC] scores, carotid intima–media thickness, peripheral arterial disease, and pulse wave velocity), in addition to Framingham risk scores for predicting coronary heart disease. Only the CAC was shown to add significantly to the Framingham risk score in predicting coronary heart disease.

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Most Popular Internal Medicine Articles

Last month's top read Top Articles of 2012

1 Walking Versus Running for Hypertension, Cholesterol, and Diabetes Mellitus Risk Reduction Arteriosclerosis, Thrombosis, and Vascular Biology, April 17, 2013

2 Canagliflozin Compared With Sitagliptin for Patients With Type 2 Diabetes Who Do Not Have Adequate Glycemic Control With Metformin Plus Sulfonylurea: A 52-week randomized trial Diabetes Care, April 9, 2013

3 Vitamin D Levels for Preventing Acute Coronary Syndrome and Mortality: Evidence of a Non-Linear Association Journal of Clinical Endocrinology and Metabolism, March 27, 2013
Exclusive Author Commentary

4 Treatment of Iron-deficiency Anemia in Patients with Subclinical Hypothyroidism American Journal of Medicine, April 18, 2013

5 Testosterone and cardiovascular risk Internal and Emergency Medicine, March 21, 2013

6 Effects of vitamin D supplementation on body fat accumulation, inflammation, and metabolic risk factors in obese adults with low vitamin D levels -- Results from a randomized trial European Journal of Internal Medicine , April 11, 2013

7 The endocrinology of exercise Internal and Emergency Medicine, March 27, 2013 Review Article
Exclusive Author Commentary

8 The Importance of 24-Hour Ambulatory Blood Pressure Monitoring in Patients at Risk of Cardiovascular Events High Blood Pressure & Cardiovascular Prevention, April 16, 2013

9 Predictors of diabetic nephropathy Central European Journal of Medicine, April 23, 2013

10 Masked Hypertension in Diabetes Mellitus-Treatment Implications for Clinical Practice Hypertension, April 19, 2013

11 Antihypertensive therapy: nocturnal dippers and nondippers. Do we treat them differently? Vascular Health and Risk Management, March 26, 2013 Free full text

12 Detecting and controlling diabetic nephropathy: What do we know? Cleveland Clinic Journal of Medicine, April 3, 2013 Free full text

13 Bariatric surgery for type 2 diabetes The Lancet, March 20, 2013

14 Sitagliptin pretreatment in diabetes patients presenting with acute coronary syndrome: results from the Acute Coronary Syndrome Israeli Survey (ACSIS) Cardiovascular Diabetology, March 29, 2013 Free full text

15 Effect of Morbid Obesity on In-Hospital Mortality and Coronary Revascularization Outcomes After Acute Myocardial Infarction in the United States The American Journal of Cardiology, April 5, 2013

16 Teriparatide for Idiopathic Osteoporosis in Premenopausal Women: A Pilot Study Journal of Clinical Endocrinology and Metabolism, April 5, 2013

17 Comparison of Diabetic Ketoacidosis in Patients With Type-1 and Type-2 Diabetes Mellitus The American Journal of the Medical Sciences, April 1, 2013

18 The impact of coffee on health Maturitas, February 26, 2013

19 Mortality and Morbidity During and After Antihypertensive and Lipid-Lowering Treatment to Prevent Heart Attack Trial Hypertension, April 19, 2013

20 Vildagliptin in addition to metformin improves retinal blood flow and erythrocyte deformability in patients with type 2 diabetes mellitus -- results from an exploratory study Cardiovascular Diabetology, April 12, 2013 Free full text

Indexed Journals in Internal Medicine: New England Journal of Medicine, The Lancet, Archives of Internal Medicine more

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Internal Medicine - Endocrinology News & Articles

Articles

Clinical Pearls in Internal Medicine

Highlights in Internal Medicine

Vitamin D deficiency is associated with increased mortality in ICU patients

Coronary artery calcium increases cardiovascular risk in patients with T2DM and HTN

CAC scores add predictability to Framingham

Most Popular Internal Medicine Articles

Other Topics in Internal Medicine