Internal Medicine - Dermatology News & Articles

What makes MDLinx Internal Medicine different from all the other primary care literature reviews? Our team of medical editors read over 2,000 medical journals every day so you can stay current in less than 5 minutes! They sort, rank and summarize every article that will impact your daily practice. They even mark which articles are available in free full text, which are clinical or evidence-based, and which have MDLinx Exclusive Author Commentary from the people who actually performed the research.

Also on this page you’ll see bonus content from our physician editor, D. Scott Cunningham, MD, PhD, in the form of his top highlights you can’t miss, along with clinical pearls from The Smartest Internist, a quiz competition from the editors of MDLinx Internal Medicine in collaboration with the Cleveland Clinic Center for Continuing Education.

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Articles

Latest (7) Full Text Articles (170) Focus on Depression

Ranked, sorted, and summarized by MDLinx editors from the latest literature

Topics:

1 Pituitary Tumor Transforming Gene 1 Induces Tumor Necrosis Factor-ALPHA Production from Keratinocytes: Implication for Involvement in the Pathophysiology of Psoriasis Journal of Investigative Dermatology, May 21, 2013 Review Article

2 Mechanisms of p53 Restriction in Merkel Cell Carcinoma Cells Are Independent of the Merkel Cell Polyoma Virus T Antigens Journal of Investigative Dermatology, May 21, 2013 Review Article

3 Zinc deficiency and its management in the pediatric population: A literature review and proposed etiologic classification Journal of the American Academy of Dermatology, May 21, 2013 Review Article

4 A comprehensive immunohistochemical approach of AKT/mTOR pathway and p-STAT3 in mycosis fungoides Journal of the American Academy of Dermatology, May 21, 2013 Review Article

5 A case-control study of clinicopathologic features, prognosis, and therapeutic responses in patients with granulomatous mycosis fungoides Journal of the American Academy of Dermatology, May 21, 2013 Review Article

6 Significantly High Levels of Anti-dsDNA Immunoglobulin E in Sera and the Ability of dsDNA to Induce the Degranulation of Basophils from Chronic Urticaria Patients International Archives of Allergy and Immunology, May 21, 2013 Clinical Article

7 Genetic Heterogeneity in Type III Familial Cutaneous Syndactyly and Linkage to Chromosome 7q36 American Journal of Medical Genetics Part A, May 21, 2013 Review Article

Prior Articles

8 The Chemopreventive Efficacies of Nonsteroidal Anti-inflammatory Drugs: the Relationship of Short-term Biomarkers to Long-term Skin Tumor Outcome Cancer Prevention Research, May 20, 2013 Clinical Article

9 Alleged isotretinoin-associated inflammatory bowel disease: Disproportionate reporting by attorneys to the Food and Drug Administration Adverse Event Reporting System Journal of the American Academy of Dermatology, May 20, 2013 Review Article

10 Online learning in a dermatology clerkship: Piloting the new American Academy of Dermatology Medical Student Core Curriculum Journal of the American Academy of Dermatology, May 20, 2013 Review Article

11 Elastic staining versus fluorescent and polarized microscopy in the diagnosis of alopecia Journal of the American Academy of Dermatology, May 20, 2013 Review Article

12 The IL23R A/Gln381 Allele Promotes IL-23 Unresponsiveness in Human Memory -Helper 17 Cells and Impairs Th17 Responses in Psoriasis Patients Journal of Investigative Dermatology, May 20, 2013 Review Article

13 E- to N-cadherin switch in melanoma is associated with decreased expression of PTEN and cancer progression British Journal of Dermatology, May 17, 2013 Review Article

14 The CD133+ cell content correlates with tumor growth in melanomas from skin with chronic sun-induced damage British Journal of Dermatology, May 17, 2013 Review Article

15 Factors Predictive of Recurrence and Death From Cutaneous Squamous Cell Carcinoma A 10-Year, Single-Institution Cohort Study Recurrence and Death From CSCC JAMA Dermatology, May 17, 2013 Clinical Article

16 Clinical and Histopathological Features of Folliculotropic Mycosis Fungoides: A Norwegian Patient Series Acta Dermato-Venereologica, May 17, 2013 Review Article

17 Use of Copper Alloy for Preventing Transmission of Methicillin-resistant Staphylococcus aureus Contamination in the Dermatology Ward Acta Dermato-Venereologica, May 17, 2013 Review Article

18 Tumour Necrosis Factor-alpha and Matrix Metalloproteinase-2 are Expressed Strongly in Hidradenitis Suppurativa Acta Dermato-Venereologica, May 17, 2013 Review Article

19 In vitro drug causality assessment in Stevens-Johnson syndrome - alternatives for lymphocyte transformation test Clinical & Experimental Allergy, May 17, 2013 Clinical Article

20 Case of diffuse cutaneous systemic sclerosis with anti-Ku and anti-centromere antibodies The Journal of Dermatology, May 17, 2013

50 available pages FirstPrevious 1 2 3 4 5 6 7 8 9 10 Next Last

Clinical Pearls in Internal Medicine

Vitamin D deficiency is more common with non-Caucasian patients, and those with lower social support, no insurance, diabetes, lower activity levels, higher parathyroid hormone levels, and higher body mass indexes
Eating an early breakfast and dinner when taking PPIs can lower FSSG scores and improve GERD symptoms. (Factors leading to increased FSSG scores were female gender, inadequate sleep, lack of breakfast, antihypertensive agent non-users and dinner just before bedtime.)
No single method of contraception is contraindicated by age alone, but caution should be exercised with estrogen-containing preparations in obese women over 40

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Highlights in Internal Medicine

Vitamin D deficiency is associated with increased mortality in ICU patients

Among 130 patients requiring mechanical ventilation, 107 were vitamin D-deficient (< 20 ng/ml). Of the patients who did not survive, the length of survival was shorter in the vitamin D-deficient patients (15.3 vs. 24.2 days, respectively).

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Coronary artery calcium increases cardiovascular risk in patients with T2DM and HTN

Researchers at Tel-Aviv University have conducted a study to determine the value of coronary artery calcium (CAC) measurements in cardiovascular risk stratification in patients with T2DM and HTN. The study involved 423 patients enrolled in the International Nifedipine Study: Intervention as Goal for Hypertension Therapy. The patients had baseline CT scans for CAC measurement at baseline and were shown to be free of disease. Follow-up CT scans were performed at 3 and 15 years. Cardiovascular events (CVEs) occurred in 41 of 423 patients at 3 years and 111 of 268 patients at 15 years of follow-up. CVEs occurred in 15% and 52% (CAC+) and 7% and 32% (CAC-) of patients with T2DM at 3 and 15 years of follow-up, respectively. Compared to patients without T2DM and no CAC, the HRs for a CVE were 6.6 and 3.9 in T2DM patients with and without CAC, respectively.

Read the article summary

CAC scores add predictability to Framingham

Researchers at Erasmus University Medical Center in Rotterdam have evaluated 12 measures (N-terminal fragment of prohormone B-type natriuretic peptide levels, von Willebrand factor antigen levels, fibrinogen levels, chronic kidney disease, leukocyte count, C-reactive protein levels, homocysteine levels, uric acid levels, coronary artery calcium [CAC] scores, carotid intima–media thickness, peripheral arterial disease, and pulse wave velocity), in addition to Framingham risk scores for predicting coronary heart disease. Only the CAC was shown to add significantly to the Framingham risk score in predicting coronary heart disease.

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Most Popular Internal Medicine Articles

Last month's top read Top Articles of 2012

1 Effect of vitamin D supplementation and ultraviolet B exposure on serum 25-hydroxyvitamin D concentrations in healthy volunteers: a randomized, crossover clinical trial British Journal of Dermatology, April 2, 2013

2 Outpatient parenteral antimicrobial therapy British Medical Journal, April 12, 2013

3 A clinical study of melasma and a comparison of the therapeutic effect of certain currently available topical modalities for its treatment Indian Journal of Dermatology, April 22, 2013 Free full text

4 Focusing and depth of field in photography: application in dermatology practice Skin Research and Technology, April 3, 2013 Review Article

5 Prevention of nonsteroidal inflammatory drug-induced urticaria and/or angioedema Annals of Allergy, Asthma, and Immunology, March 28, 2013

6 Surgeon error and slide quality during Mohs micrographic surgery: Is there a relationship with tumor recurrence Journal of the American Academy of Dermatology, April 16, 2013
Exclusive Author Commentary

7 Skin Conditions of Baseball, Cricket, and Softball Players Sports Medicine, April 5, 2013 Review Article

8 Practical guidelines for the use of steroid-sparing agents in the treatment of chronic pruritus Dermatologic Therapy, April 10, 2013

9 Diet and nutrition in psoriasis: analysis of the National Health and Nutrition Examination Survey (NHANES) in the United States Journal of the European Academy of Dermatology and Venereology, March 5, 2013 Review Article

10 The comparative effectiveness of suction-curettage and onabotulinumtoxin-A injections for the treatment of primary focal axillary hyperhidrosis: A randomized control trial Journal of the American Academy of Dermatology, April 16, 2013

11 The use of green tea extract in cosmetic formulations: not only an antioxidant active ingredient Dermatologic Therapy, March 14, 2013

12 Serum Ferritin and Vitamin D in Female Hair Loss: Do They Play a Role Skin Pharmacology and Physiology, February 20, 2013

13 Phase I/II and Pharmacodynamic Study of Dovitinib (TKI258)-an Inhibitor of Fibroblast Growth Factor Receptors and VEGF Receptors-in Patients with Advanced Melanoma Clinical Cancer Research, October 7, 2011 Free full text

14 New era of biologic therapeutics in atopic dermatitis Expert Opinion on Biological Therapy, March 21, 2013

15 A Systematic Review of SAPHO Syndrome and Inflammatory Bowel Disease Association Digestive Diseases and Sciences, April 16, 2013

16 Common Misconceptions About Lyme Disease American Journal of Medicine, March 7, 2013 Review Article

17 Psoriasis Is Not Associated with Atherosclerosis and Incident Cardiovascular Events: The Rotterdam Study Journal of Investigative Dermatology, April 15, 2013

18 Clinical activity and safety of combination therapy with temsirolimus and bevacizumab for advanced melanoma: A Phase II trial (CTEP 7190/ Mel47) Clinical Cancer Research, April 26, 2013

19 Chloroquine Promotes Apoptosis in Melanoma Cells by Inhibiting BH3 Domain–Mediated PUMA Degradation Journal of Investigative Dermatology, March 27, 2013

20 The relationship between severity of the disease and circulating nucleosomes in psoriasis patients Archives of Dermatological Research, April 16, 2013

Indexed Journals in Internal Medicine: New England Journal of Medicine, The Lancet, Archives of Internal Medicine more

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Internal Medicine - Dermatology News & Articles

Articles

Prior Articles

Clinical Pearls in Internal Medicine

Highlights in Internal Medicine

Vitamin D deficiency is associated with increased mortality in ICU patients

Coronary artery calcium increases cardiovascular risk in patients with T2DM and HTN

CAC scores add predictability to Framingham

Most Popular Internal Medicine Articles

Other Topics in Internal Medicine