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Internal Medicine - Clinical Pharmacology News & Articles

What makes MDLinx Internal Medicine different from all the other primary care literature reviews? Our team of medical editors read over 2,000 medical journals every day so you can stay current in less than 5 minutes! They sort, rank and summarize every article that will impact your daily practice. They even mark which articles are available in free full text, which are clinical or evidence-based, and which have MDLinx Exclusive Author Commentary from the people who actually performed the research.

Also on this page you’ll see bonus content from our physician editor, D. Scott Cunningham, MD, PhD, in the form of his top highlights you can’t miss, along with clinical pearls from The Smartest Internist, a quiz competition from the editors of MDLinx Internal Medicine in collaboration with the Cleveland Clinic Center for Continuing Education.

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Articles

Latest (12) Full Text Articles (994) Focus on Angina
Ranked, sorted, and summarized by MDLinx editors from the latest literature
Topics:

1 Targeted use of heparin, heparinoids, or low-molecular-weight heparin to improve outcome after acute ischaemic stroke: an individual patient data meta-analysis of randomised controlled trials The Lancet Neurology, May 17, 2013    Evidence Based Medicine    Review Article    Clinical Article

2 Cost-Effectiveness of Duloxetine in Chronic Low Back Pain: A Quebec Societal Perspective Spine, May 17, 2013    Evidence Based Medicine    Clinical Article

3 Impact of Adding Ezetimibe to Statin to Achieve Low-Density Lipoprotein Cholesterol Goal (from the Clinical Outcomes Utilizing Revascularization and Aggressive Drug Evaluation [COURAGE] Trial) The American Journal of Cardiology, May 17, 2013    Clinical Article

4 Prescription Opioids for Back Pain and Use of Medications for Erectile Dysfunction Spine, May 17, 2013    Evidence Based Medicine    Clinical Article

5 Spinal Injection Therapy for Low Back Pain JAMA, May 17, 2013    Clinical Article

6 Adulterated Sexual Enhancement Supplements: More Than Mojo JAMA Internal Medicine, May 17, 2013    Review Article    Clinical Article

7 A dose-ranging study of cabozantinib in men with castration-resistant prostate cancer and bone metastases Clinical Cancer Research, May 17, 2013    Clinical Article

8 Anti tumor Necrosis Factor - Alpha Adalimumab for Complex Regional Pain Syndrome Type 1 (CRPS-I): A Case Series Pain Practice, May 17, 2013    Clinical Article

9 Triple therapy with deferiprone, idebenone and riboflavin in Friedreich's ataxia – open-label trial Acta Neurologica Scandinavica, May 17, 2013    Clinical Article

10 Phenothiazines Inhibit Hepatitis C Virus Entry, Likely by Increasing the Fluidity of Cholesterol-Rich Membranes Antimicrobial Agents and Chemotherapy, May 17, 2013    Review Article

11 Influence of compliance on bone mineral density changes in postmenopausal women with early breast cancer on Anastrozole Journal of Cancer Research & Clinical Oncology, May 17, 2013    Clinical Article

12 Cost analysis of glatiramer acetate vs. fingolimod for the treatment of patients with relapsing-remitting multiple sclerosis in Spain Full Text Health Economics Review, May 17, 2013    Clinical Article

Prior Articles

13 Ibuprofen with or without an antiemetic for acute migraine headaches in adults Cochrane Reviews, May 16, 2013    Evidence Based Medicine    Clinical Article

14 Differential Effects of Nebivolol Versus Metoprolol on Functional Sympatholysis in Hypertensive Humans Hypertension, May 16, 2013    Clinical Article

15 Interventions to improve antibiotic prescribing practices for hospital inpatients Cochrane Reviews, May 16, 2013    Evidence Based Medicine

16 Galantamine for vascular cognitive impairment Cochrane Reviews, May 16, 2013    Evidence Based Medicine    Clinical Article

17 Pharmacokinetic Considerations for the Use of Levodopa in the Treatment of Parkinson Disease: Focus on Levodopa/Carbidopa/Entacapone for Treatment of Levodopa-Associated Motor Complications Clinical Neuropharmacology, May 16, 2013    Clinical Article

18 Differential Effects of the (beta)-Adrenoceptor Blockers Carvedilol and Metoprolol on SQT1- and SQT2-Mutant Channels Journal of Cardiovascular Electrophysiology, May 16, 2013    Clinical Article

19 Tardive Dyskinesia Caused by Tetrabenazine Clinical Neuropharmacology, May 16, 2013    Clinical Article

20 Relationship between aspirin/clopidogrel resistance and intra-stent thrombi assessed by follow-up optical coherence tomography after drug-eluting stent implantation European Heart Journal – Cardiovascular Imaging, May 16, 2013    Clinical Article

50 available pages FirstPrevious 1 2 3 4 5 6 7 8 9 10 Next Last

Clinical Pearls in Internal Medicine

Highlights in Internal Medicine

Vitamin D deficiency is associated with increased mortality in ICU patients

Among 130 patients requiring mechanical ventilation, 107 were vitamin D-deficient (< 20 ng/ml). Of the patients who did not survive, the length of survival was shorter in the vitamin D-deficient patients (15.3 vs. 24.2 days, respectively).

Read the article summary

Coronary artery calcium increases cardiovascular risk in patients with T2DM and HTN

Researchers at Tel-Aviv University have conducted a study to determine the value of coronary artery calcium (CAC) measurements in cardiovascular risk stratification in patients with T2DM and HTN. The study involved 423 patients enrolled in the International Nifedipine Study: Intervention as Goal for Hypertension Therapy. The patients had baseline CT scans for CAC measurement at baseline and were shown to be free of disease. Follow-up CT scans were performed at 3 and 15 years. Cardiovascular events (CVEs) occurred in 41 of 423 patients at 3 years and 111 of 268 patients at 15 years of follow-up. CVEs occurred in 15% and 52% (CAC+) and 7% and 32% (CAC-) of patients with T2DM at 3 and 15 years of follow-up, respectively. Compared to patients without T2DM and no CAC, the HRs for a CVE were 6.6 and 3.9 in T2DM patients with and without CAC, respectively.

Read the article summary

CAC scores add predictability to Framingham

Researchers at Erasmus University Medical Center in Rotterdam have evaluated 12 measures (N-terminal fragment of prohormone B-type natriuretic peptide levels, von Willebrand factor antigen levels, fibrinogen levels, chronic kidney disease, leukocyte count, C-reactive protein levels, homocysteine levels, uric acid levels, coronary artery calcium [CAC] scores, carotid intima–media thickness, peripheral arterial disease, and pulse wave velocity), in addition to Framingham risk scores for predicting coronary heart disease. Only the CAC was shown to add significantly to the Framingham risk score in predicting coronary heart disease.

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Most Popular Internal Medicine Articles

Last month's top read Top Articles of 2012

1 Outcomes of apixaban vs. warfarin by type and duration of atrial fibrillation: results from the ARISTOTLE trial European Heart Journal, April 22, 2013

2 Renin-angiotensin system inhibitors for prevention of recurrent atrial fibrillation: a meta-analysis International Journal of Clinical Practice, April 9, 2013    Evidence Based Medicine    Review Article

3 Chlorthalidone Versus Hydrochlorothiazide for the Treatment of Hypertension in Older Adults A Population-Based Cohort Study Annals of Internal Medicine, March 19, 2013

4 Efficacy and Effects on Lipid Metabolism of Combination Treatment With Losartan + Hydrochlorothiazide Versus Losartan + Amlodipine: A 48-Week Prospective, Multicenter, Randomized, Open-Label Trial Clinical Therapeutics, April 22, 2013

5 L-Carnitine in the Secondary Prevention of Cardiovascular Disease: Systematic Review and Meta-analysis Mayo Clinic Proceedings, April 19, 2013    Evidence Based Medicine    Review Article

6 Rivaroxaban for Thromboprophylaxis in Acutely Ill Medical Patients New England Journal of Medicine, March 15, 2013

7 Effects of pravastatin on serum adiponectin levels in female patients with type 2 diabetes mellitus Atherosclerosis, March 12, 2013

8 Corticosteroids for preventing postherpetic neuralgia Cochrane Reviews, April 3, 2013    Evidence Based Medicine

9 Vitamin D Levels for Preventing Acute Coronary Syndrome and Mortality: Evidence of a Non-Linear Association Journal of Clinical Endocrinology and Metabolism, March 27, 2013
Exclusive Author Commentary

10 Antihypertensive therapy: nocturnal dippers and nondippers. Do we treat them differently? Vascular Health and Risk Management, March 26, 2013    Free full text

11 Advances in Stroke Prevention in Atrial Fibrillation: Enhanced Risk Stratification Combined With the Newer Oral Anticoagulants Clinical Cardiology, April 11, 2013    Free full text    Review Article

12 Leukaemia update. Part 1: diagnosis and management British Medical Journal, April 9, 2013    Review Article

13 Use and indications of cholestyramine and bile acid sequestrants Internal and Emergency Medicine, April 9, 2013    Review Article

14 Cardiovascular events after clarithromycin use in lower respiratory tract infections: analysis of two prospective cohort studies British Medical Journal, April 10, 2013    Free full text

15 Effect of Disodium EDTA Chelation Regimen on Cardiovascular Events in Patients With Previous Myocardial Infarction: The TACT Randomized Trial JAMA, March 27, 2013    Evidence Based Medicine

16 Cardiac Magnetic Resonance Imaging in the Evaluation of the Late Effects of Anthracyclines Among Long-Term Survivors of Childhood Cancer JACC - Journal of the American College of Cardiology, April 3, 2013

17 Long-term efficacy and safety of subcutaneous pasireotide in acromegaly: results from an open-ended, multicenter, Phase II extension study Pituitary, March 28, 2013

18 Proton Pump Inhibitors and Risk of 1-Year Mortality and Rehospitalization in Older Patients Discharged From Acute Care Hospitals Proton Pump Inhibitors in Older Patients JAMA Internal Medicine, April 10, 2013

19 Chronic Kidney Disease and Diabetes Mellitus Predict Resistance to Vitamin D Replacement Therapy The American Journal of the Medical Sciences, April 1, 2013

20 Dental Prophylaxis and Periodontal Treatment Are Protective Factors to Ischemic Stroke Stroke, April 10, 2013

Indexed Journals in Internal Medicine: New England Journal of Medicine, The Lancet, Archives of Internal Medicinemore

Other Topics in Internal Medicine

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