Internal Medicine - Epidemiology News & Articles

What makes MDLinx Internal Medicine different from all the other primary care literature reviews? Our team of medical editors read over 2,000 medical journals every day so you can stay current in less than 5 minutes! They sort, rank and summarize every article that will impact your daily practice. They even mark which articles are available in free full text, which are clinical or evidence-based, and which have MDLinx Exclusive Author Commentary from the people who actually performed the research.

Also on this page you’ll see bonus content from our physician editor, D. Scott Cunningham, MD, PhD, in the form of his top highlights you can’t miss, along with clinical pearls from The Smartest Internist, a quiz competition from the editors of MDLinx Internal Medicine in collaboration with the Cleveland Clinic Center for Continuing Education.

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Articles

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Ranked, sorted, and summarized by MDLinx editors from the latest literature

Topics:

381 Modulation by Dietary Fat and Carbohydrate of IRS1 Association With Type 2 Diabetes Traits in Two Populations of Different Ancestries Diabetes Care, April 19, 2013 Review Article

382 Evidence of Reduced Beta Cell Function in Asian Indians With Mild Dysglycemia Diabetes Care, April 19, 2013 Review Article

383 Randomized Trial of Physician Alerts for Thromboprophylaxis after Discharge American Journal of Medicine, April 19, 2013 Evidence Based Medicine

384 Premature Mortality Patterns Among American Indians in South Dakota, 2000-2010 American Journal of Preventive Medicine, April 19, 2013 Review Article

385 Carbapenem-resistant Acinetobacter baumannii: epidemiology, surveillance and management Expert Review of Anti-infective Therapy, April 19, 2013 Clinical Article

386 New IASLC/ATS/ERS Classification and Invasive Tumor Size are Predictive of Disease Recurrence in Stage I Lung Adenocarcinoma Journal of Thoracic Oncology, April 19, 2013 Clinical Article

387 NF-YA Underlies EZH2 Upregulation and Is Essential for Proliferation of Human Epithelial Ovarian Cancer Cells Molecular Cancer Research, April 19, 2013 Review Article Clinical Article

388 Pattern of dietary carbohydrate intake among urbanized adult Nigerians International Journal of Food Sciences and Nutrition, April 19, 2013 Clinical Article

389 Is breast cancer in young Asian women more aggressive than in Caucasians- A cross-sectional analysis Tumor Biology, April 19, 2013 Review Article

390 Implementing the ACHIEVE Model to Prevent and Reduce Chronic Disease in Rural Klickitat County, Washington Full Text Preventing Chronic Disease, April 19, 2013 Review Article

391 Prevalence of Waterpipe Tobacco Smoking Among Population Aged 15 Years or Older, Vietnam, 2010 Full Text Preventing Chronic Disease, April 19, 2013 Clinical Article
Exclusive Author Commentary

392 Meta-analysis of adverse health effects due to air pollution in Chinese populations Full Text BMC Public Health, April 19, 2013 Evidence Based Medicine

393 Thinking on your feet: A qualitative evaluation of sit-stand desks in an Australian workplace Full Text BMC Public Health, April 19, 2013 Review Article

394 Assessment of maternal anemia in rural Western China between 2001 and 2005: a two-level logistic regression approach Full Text BMC Public Health, April 19, 2013 Review Article

395 The influence of culture in the oral expression of pain: comparative study between French and Syrian cancer patients Bulletin du Cancer, April 19, 2013 Review Article

396 Awareness of cervical cancer, Papanicolau's smear and its utilization among female, final year undergraduates in Durban, South Africa Journal of Cancer Research and Therapeutics, April 19, 2013 Clinical Article

397 Developing a Performance Data Suite to Facilitate Lean Improvement in a Chemotherapy Day Unit Journal of Oncology Practice, April 19, 2013 Review Article

398 Patterns of Care in Palliative Radiotherapy: A Population-Based Study Journal of Oncology Practice, April 19, 2013 Clinical Article

399 Cancer prevalence estimates in Europe at the beginning of 2000 Annals of Oncology, April 19, 2013 Review Article

400 Biolimus-eluting biodegradable polymer-coated stent versus durable polymer-coated sirolimus-eluting stent in unselected patients receiving percutaneous coronary intervention (SORT OUT V): a randomised non-inferiority trial The Lancet, April 18, 2013 Clinical Article

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Clinical Pearls in Internal Medicine

Vitamin D deficiency is more common with non-Caucasian patients, and those with lower social support, no insurance, diabetes, lower activity levels, higher parathyroid hormone levels, and higher body mass indexes
Eating an early breakfast and dinner when taking PPIs can lower FSSG scores and improve GERD symptoms. (Factors leading to increased FSSG scores were female gender, inadequate sleep, lack of breakfast, antihypertensive agent non-users and dinner just before bedtime.)
No single method of contraception is contraindicated by age alone, but caution should be exercised with estrogen-containing preparations in obese women over 40

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Highlights in Internal Medicine

Vitamin D deficiency is associated with increased mortality in ICU patients

Among 130 patients requiring mechanical ventilation, 107 were vitamin D-deficient (< 20 ng/ml). Of the patients who did not survive, the length of survival was shorter in the vitamin D-deficient patients (15.3 vs. 24.2 days, respectively).

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Coronary artery calcium increases cardiovascular risk in patients with T2DM and HTN

Researchers at Tel-Aviv University have conducted a study to determine the value of coronary artery calcium (CAC) measurements in cardiovascular risk stratification in patients with T2DM and HTN. The study involved 423 patients enrolled in the International Nifedipine Study: Intervention as Goal for Hypertension Therapy. The patients had baseline CT scans for CAC measurement at baseline and were shown to be free of disease. Follow-up CT scans were performed at 3 and 15 years. Cardiovascular events (CVEs) occurred in 41 of 423 patients at 3 years and 111 of 268 patients at 15 years of follow-up. CVEs occurred in 15% and 52% (CAC+) and 7% and 32% (CAC-) of patients with T2DM at 3 and 15 years of follow-up, respectively. Compared to patients without T2DM and no CAC, the HRs for a CVE were 6.6 and 3.9 in T2DM patients with and without CAC, respectively.

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CAC scores add predictability to Framingham

Researchers at Erasmus University Medical Center in Rotterdam have evaluated 12 measures (N-terminal fragment of prohormone B-type natriuretic peptide levels, von Willebrand factor antigen levels, fibrinogen levels, chronic kidney disease, leukocyte count, C-reactive protein levels, homocysteine levels, uric acid levels, coronary artery calcium [CAC] scores, carotid intima–media thickness, peripheral arterial disease, and pulse wave velocity), in addition to Framingham risk scores for predicting coronary heart disease. Only the CAC was shown to add significantly to the Framingham risk score in predicting coronary heart disease.

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Most Popular Internal Medicine Articles

Last month's top read Top Articles of 2012

1 Walking Versus Running for Hypertension, Cholesterol, and Diabetes Mellitus Risk Reduction Arteriosclerosis, Thrombosis, and Vascular Biology, April 17, 2013

2 Primary Prevention of Cardiovascular Disease with a Mediterranean Diet New England Journal of Medicine, April 8, 2013 Free full text

3 Vitamin D Levels for Preventing Acute Coronary Syndrome and Mortality: Evidence of a Non-Linear Association Journal of Clinical Endocrinology and Metabolism, March 27, 2013
Exclusive Author Commentary

4 Effect of seven-day atorvastatin pretreatment on the incidence of periprocedural myocardial infarction following percutaneous coronary intervention in patients receiving long-term statin therapy. A randomized study International Journal of Cardiology, April 19, 2013

5 Preeclampsia as a Risk Factor for Diabetes: A Population-Based Cohort Study PLoS Medicine, April 19, 2013 Free full text

6 Menopausal Hormone Therapy for the Primary Prevention of Chronic Conditions: U.S. Preventive Services Task Force Recommendation Statement Annals of Internal Medicine, March 6, 2013 Free full text Clinical Guideline

7 Atherosclerosis across 4000 years of human history: the Horus study of four ancient populations The Lancet, March 26, 2013

8 Septic shock: The initial moments and beyond Cleveland Clinic Journal of Medicine, March 5, 2013 Free full text Review Article

9 Meta-Analysis of Impact of Different Types and Doses of Statins on New-Onset Diabetes Mellitus The American Journal of Cardiology, April 4, 2013 Evidence Based Medicine Review Article

10 The relationship between self-rated health and objective health status: a population-based study BMC Public Health, April 10, 2013 Free full text Review Article

11 Ideal Cardiovascular Health Is Inversely Associated With Incident Cancer Circulation, March 27, 2013

12 Risk of Ischemic Heart Disease in Women after Radiotherapy for Breast Cancer New England Journal of Medicine, March 21, 2013

13 Closure of Patent Foramen Ovale versus Medical Therapy after Cryptogenic Stroke New England Journal of Medicine, March 25, 2013

14 Trajectories of cardiometabolic risk factors before diagnosis of three subtypes of type 2 diabetes: a post-hoc analysis of the longitudinal Whitehall II cohort study The Lancet, March 20, 2013

15 Right ventricular hypertrophy in systemic hypertension: an updated review of clinical studies Journal of Hypertension, April 8, 2013 Review Article

16 Frailty in older adults: Implications for end-of-life care Cleveland Clinic Journal of Medicine, March 19, 2013 Free full text

17 Short-term intensive insulin therapy in type 2 diabetes mellitus: a systematic review and meta-analysis The Lancet, March 20, 2013 Evidence Based Medicine Review Article

18 Trajectories of cardiometabolic risk factors before diagnosis of three subtypes of type 2 diabetes: a post-hoc analysis of the longitudinal Whitehall II cohort study The Lancet, March 11, 2013

19 Prevalence and prognostic role of anaemia in patients with acute heart failure and preserved or depressed ventricular function Internal and Emergency Medicine, March 8, 2013

20 Economic Costs of Diabetes in the U.S. in 2012 Diabetes Care, March 8, 2013 Review Article

Indexed Journals in Internal Medicine: New England Journal of Medicine, The Lancet, Archives of Internal Medicine more

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Internal Medicine - Epidemiology News & Articles

Articles

Clinical Pearls in Internal Medicine

Highlights in Internal Medicine

Vitamin D deficiency is associated with increased mortality in ICU patients

Coronary artery calcium increases cardiovascular risk in patients with T2DM and HTN

CAC scores add predictability to Framingham

Most Popular Internal Medicine Articles

Other Topics in Internal Medicine