What makes MDLinx Internal Medicine different from all the other primary care literature reviews? Our team of medical editors read over 2,000 medical journals every day so you can stay current in less than 5 minutes! They sort, rank and summarize every article that will impact your daily practice. They even mark which articles are available in free full text, which are clinical or evidence-based, and which have MDLinx Exclusive Author Commentary from the people who actually performed the research.
Also on this page you’ll see bonus content from our physician editor, D. Scott Cunningham, MD, PhD, in the form of his top highlights you can’t miss, along with clinical pearls from The Smartest Internist, a quiz competition from the editors of MDLinx Internal Medicine in collaboration with the Cleveland Clinic Center for Continuing Education.
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221 Association between habitual physical activity and lower cardiovascular risk in premenopausal, perimenopausal, and postmenopausal women: a population-based study Menopause, April 26, 2013
222 Reduction of Stent Thrombosis in Patients with Acute Coronary Syndrome Treated with Rivaroxaban in ATLAS ACS 2-TIMI 51 JACC - Journal of the American College of Cardiology, April 26, 2013 Clinical Article
223 Hepatic Dysfunction in Ambulatory Patients with Heart Failure - Application of the MELD Scoring System for Outcome Prediction JACC - Journal of the American College of Cardiology, April 26, 2013 Clinical Article
224 Incidence and risk factors for very late recurrence of atrial fibrillation after radiofrequency catheter ablation EP Europace, April 26, 2013 Clinical Article
225 Platelet REsponsiveness to CLOpidogrel treatment after Peripheral endovascular procedures - The PRECLOP study: Clinical Impact and Optimal Cut-off Value of High On Treatment Platelet Reactivity JACC - Journal of the American College of Cardiology, April 26, 2013 Clinical Article
226 Clinical Outcome Following Stringent Discontinuation of Dual Anti-Platelet Therapy After 12 Months in Real-World Patients Treated With Second-Generation Zotarolimus-Eluting Resolute and Everolimus-Eluting Xience V Stents: Two-Year Follow-up of the Randomized TWENTE Trial JACC - Journal of the American College of Cardiology, April 26, 2013
227 B-Type Natriuretic Peptide and Survival in Hypertrophic Cardiomyopathy JACC - Journal of the American College of Cardiology, April 26, 2013
228 Early impairment of contractility reserve in patients with insulin resistance in comparison with healthy subjects Full Text Cardiovascular Diabetology, April 26, 2013 Clinical Article
229 Sample size determinations in original research protocols for randomised clinical trials submitted to UK research ethics committees: review British Medical Journal, April 26, 2013 Evidence Based Medicine
230 Trends in mammography screening rates after publication of the 2009 US Preventive Services Task Force recommendations Cancer, April 26, 2013 Review Article Clinical Guideline
231
High-sensitivity C-reactive protein and white blood cell count equally predict development of the metabolic syndrome in a Japanese health screening population
Acta Diabetologia, April 26, 2013
Review Article
Exclusive Author Commentary
232 Nonalcoholic fatty liver and metabolic syndrome in Italy: results from a multicentric study of the Italian Arteriosclerosis society Acta Diabetologia, April 26, 2013 Review Article
233 An analysis of competing mortality risks among colorectal cancer survivors in Queensland, 1996-2009 Cancer Causes and Control, April 26, 2013 Review Article
234 Clinical Epidemiology (CE) and Evidence-Based Medicine (EBM) in the Asia Pacific region (Round Table Forum) Preventive Medicine, April 26, 2013 Review Article
235 A comparison of smoking behaviour characteristics between Caucasian smokers in United Kingdom and Malay smokers in Malaysia Preventive Medicine, April 26, 2013 Clinical Article
236 The Childhood Leukemia International Consortium Cancer Epidemiology, April 26, 2013 Review Article
237 Co-Occurrence of Leading Lifestyle-Related Chronic Conditions Among Adults in the United States, 2002-2009 Full Text Preventing Chronic Disease, April 26, 2013 Clinical Article
238 Multiple Chronic Conditions Among US Adults Who Visited Physician Offices: Data From the National Ambulatory Medical Care Survey, 2009 Full Text Preventing Chronic Disease, April 26, 2013 Review Article
239 Prevalence of Multiple Chronic Conditions Among US Adults: Estimates From the National Health Interview Survey, 2010 Full Text Preventing Chronic Disease, April 26, 2013 Clinical Article
240 Prevalence of Multiple Chronic Conditions Among Medicare Beneficiaries, United States, 2010 Full Text Preventing Chronic Disease, April 26, 2013 Review Article
Among 130 patients requiring mechanical ventilation, 107 were vitamin D-deficient (< 20 ng/ml). Of the patients who did not survive, the length of survival was shorter in the vitamin D-deficient patients (15.3 vs. 24.2 days, respectively).
Read the article summaryResearchers at Tel-Aviv University have conducted a study to determine the value of coronary artery calcium (CAC) measurements in cardiovascular risk stratification in patients with T2DM and HTN. The study involved 423 patients enrolled in the International Nifedipine Study: Intervention as Goal for Hypertension Therapy. The patients had baseline CT scans for CAC measurement at baseline and were shown to be free of disease. Follow-up CT scans were performed at 3 and 15 years. Cardiovascular events (CVEs) occurred in 41 of 423 patients at 3 years and 111 of 268 patients at 15 years of follow-up. CVEs occurred in 15% and 52% (CAC+) and 7% and 32% (CAC-) of patients with T2DM at 3 and 15 years of follow-up, respectively. Compared to patients without T2DM and no CAC, the HRs for a CVE were 6.6 and 3.9 in T2DM patients with and without CAC, respectively.
Read the article summaryResearchers at Erasmus University Medical Center in Rotterdam have evaluated 12 measures (N-terminal fragment of prohormone B-type natriuretic peptide levels, von Willebrand factor antigen levels, fibrinogen levels, chronic kidney disease, leukocyte count, C-reactive protein levels, homocysteine levels, uric acid levels, coronary artery calcium [CAC] scores, carotid intima–media thickness, peripheral arterial disease, and pulse wave velocity), in addition to Framingham risk scores for predicting coronary heart disease. Only the CAC was shown to add significantly to the Framingham risk score in predicting coronary heart disease.
Read the article summary1 Walking Versus Running for Hypertension, Cholesterol, and Diabetes Mellitus Risk Reduction Arteriosclerosis, Thrombosis, and Vascular Biology, April 17, 2013
2 Primary Prevention of Cardiovascular Disease with a Mediterranean Diet New England Journal of Medicine, April 8, 2013 Free full text
3
Vitamin D Levels for Preventing Acute Coronary Syndrome and Mortality: Evidence of a Non-Linear Association
Journal of Clinical Endocrinology and Metabolism, March 27, 2013
Exclusive Author Commentary
4 Effect of seven-day atorvastatin pretreatment on the incidence of periprocedural myocardial infarction following percutaneous coronary intervention in patients receiving long-term statin therapy. A randomized study International Journal of Cardiology, April 19, 2013
5 Preeclampsia as a Risk Factor for Diabetes: A Population-Based Cohort Study PLoS Medicine, April 19, 2013 Free full text
6 Menopausal Hormone Therapy for the Primary Prevention of Chronic Conditions: U.S. Preventive Services Task Force Recommendation Statement Annals of Internal Medicine, March 6, 2013 Free full text Clinical Guideline
7 Atherosclerosis across 4000 years of human history: the Horus study of four ancient populations The Lancet, March 26, 2013
8 Septic shock: The initial moments and beyond Cleveland Clinic Journal of Medicine, March 5, 2013 Free full text Review Article
9 Meta-Analysis of Impact of Different Types and Doses of Statins on New-Onset Diabetes Mellitus The American Journal of Cardiology, April 4, 2013 Evidence Based Medicine Review Article
10 The relationship between self-rated health and objective health status: a population-based study BMC Public Health, April 10, 2013 Free full text Review Article
11 Ideal Cardiovascular Health Is Inversely Associated With Incident Cancer Circulation, March 27, 2013
12 Risk of Ischemic Heart Disease in Women after Radiotherapy for Breast Cancer New England Journal of Medicine, March 21, 2013
13 Closure of Patent Foramen Ovale versus Medical Therapy after Cryptogenic Stroke New England Journal of Medicine, March 25, 2013
14 Trajectories of cardiometabolic risk factors before diagnosis of three subtypes of type 2 diabetes: a post-hoc analysis of the longitudinal Whitehall II cohort study The Lancet, March 20, 2013
15 Right ventricular hypertrophy in systemic hypertension: an updated review of clinical studies Journal of Hypertension, April 8, 2013 Review Article
16 Frailty in older adults: Implications for end-of-life care Cleveland Clinic Journal of Medicine, March 19, 2013 Free full text
17 Short-term intensive insulin therapy in type 2 diabetes mellitus: a systematic review and meta-analysis The Lancet, March 20, 2013 Evidence Based Medicine Review Article
18 Trajectories of cardiometabolic risk factors before diagnosis of three subtypes of type 2 diabetes: a post-hoc analysis of the longitudinal Whitehall II cohort study The Lancet, March 11, 2013
19 Prevalence and prognostic role of anaemia in patients with acute heart failure and preserved or depressed ventricular function Internal and Emergency Medicine, March 8, 2013
20 Economic Costs of Diabetes in the U.S. in 2012 Diabetes Care, March 8, 2013 Review Article
Indexed Journals in Internal Medicine: New England Journal of Medicine, The Lancet, Archives of Internal Medicine more
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