What makes MDLinx Internal Medicine different from all the other primary care literature reviews? Our team of medical editors read over 2,000 medical journals every day so you can stay current in less than 5 minutes! They sort, rank and summarize every article that will impact your daily practice. They even mark which articles are available in free full text, which are clinical or evidence-based, and which have MDLinx Exclusive Author Commentary from the people who actually performed the research.
Also on this page you’ll see bonus content from our physician editor, D. Scott Cunningham, MD, PhD, in the form of his top highlights you can’t miss, along with clinical pearls from The Smartest Internist, a quiz competition from the editors of MDLinx Internal Medicine in collaboration with the Cleveland Clinic Center for Continuing Education.
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721 Nocturnal urinary melatonin excretion is associated with non-dipper pattern in elderly hypertensives Hypertension Research, April 18, 2013 Clinical Article
722 Chinese herbal formulas for treating hypertension in traditional Chinese medicine: perspective of modern science Hypertension Research, April 18, 2013 Review Article
723 Association among blood pressure control in elderly patients with hypertension, left atrial structure and function and new-onset atrial fibrillation: a prospective 2-year study in 234 patients Hypertension Research, April 18, 2013 Clinical Article
724 Dronedarones Inhibition of If Current Is the Primary Mechanism Responsible for its Bradycardic Effect Journal of Cardiovascular Electrophysiology, April 18, 2013 Clinical Article
725 New Clinical and Electrocardiographic Classification in Patients with Idiopathic Ventricular Fibrillation Journal of Cardiovascular Electrophysiology, April 18, 2013 Clinical Article
726 Early Repolarization: A Rare Primary Arrhythmic Syndrome & Common Modifier of Arrhythmic Risk Journal of Cardiovascular Electrophysiology, April 18, 2013 Clinical Article
727 Effects of Electrical Stimulation of Carotid Baroreflex and Renal Denervation on Atrial Electrophysiology Journal of Cardiovascular Electrophysiology, April 18, 2013 Clinical Article
728 Atrial Flutter Following Pulmonary Vein Isolation: What is the mechanism Journal of Cardiovascular Electrophysiology, April 18, 2013
729 Combined Dominant Frequency and Complex Fractionated Atrial Electrogram Ablation After Circumferential Pulmonary Vein Isolation of Atrial Fibrillation Journal of Cardiovascular Electrophysiology, April 18, 2013 Clinical Article
730
Contrast-induced acute kidney injury following coronary angiography: a cohort study of hospitalized patients with or without chronic kidney disease
Nephrology Dialysis Transplantation, April 18, 2013
Clinical Article
Exclusive Author Commentary
731 Azilsartan Medoxomil/Chlorthalidone: A New Fixed-Dose Combination Antihypertensive Annals of Pharmacotherapy, April 18, 2013 Clinical Article
732 Atrial fibrillation and heart failure: beyond the heart rate Current Opinion in Cardiology, April 18, 2013 Review Article
733 Heart rate and heart failure: the role of ivabradine therapy Current Opinion in Cardiology, April 18, 2013 Review Article
734 Genetics and sudden death Current Opinion in Cardiology, April 18, 2013 Review Article
735 Novel risk factors for cardiovascular disease in rheumatoid arthritis Immunologic Research, April 18, 2013 Evidence Based Medicine Review Article Clinical Article
736 Penetrating cardiac trauma in adolescents: A rare injury with excessive mortality Journal of Pediatric Surgery, April 18, 2013 Review Article
737 Hospital-based incidence of maternal heart failure during pregnancy in Nigeria Full Text International Journal of General Medicine, April 18, 2013 Clinical Article
738 Walking Versus Running for Hypertension, Cholesterol, and Diabetes Mellitus Risk Reduction Arteriosclerosis, Thrombosis, and Vascular Biology, April 17, 2013 Clinical Article
739 The REMEDEE Trial A Randomized Comparison of a Combination Sirolimus-Eluting Endothelial Progenitor Cell Capture Stent With a Paclitaxel-Eluting Stent JACC Cardiovascular Interventions, April 17, 2013 Clinical Article
740 The Final 5-Year Follow-Up From the ENDEAVOR IV Trial Comparing a Zotarolimus-Eluting Stent With a Paclitaxel-Eluting Stent JACC Cardiovascular Interventions, April 17, 2013 Clinical Article
Among 130 patients requiring mechanical ventilation, 107 were vitamin D-deficient (< 20 ng/ml). Of the patients who did not survive, the length of survival was shorter in the vitamin D-deficient patients (15.3 vs. 24.2 days, respectively).
Read the article summaryResearchers at Tel-Aviv University have conducted a study to determine the value of coronary artery calcium (CAC) measurements in cardiovascular risk stratification in patients with T2DM and HTN. The study involved 423 patients enrolled in the International Nifedipine Study: Intervention as Goal for Hypertension Therapy. The patients had baseline CT scans for CAC measurement at baseline and were shown to be free of disease. Follow-up CT scans were performed at 3 and 15 years. Cardiovascular events (CVEs) occurred in 41 of 423 patients at 3 years and 111 of 268 patients at 15 years of follow-up. CVEs occurred in 15% and 52% (CAC+) and 7% and 32% (CAC-) of patients with T2DM at 3 and 15 years of follow-up, respectively. Compared to patients without T2DM and no CAC, the HRs for a CVE were 6.6 and 3.9 in T2DM patients with and without CAC, respectively.
Read the article summaryResearchers at Erasmus University Medical Center in Rotterdam have evaluated 12 measures (N-terminal fragment of prohormone B-type natriuretic peptide levels, von Willebrand factor antigen levels, fibrinogen levels, chronic kidney disease, leukocyte count, C-reactive protein levels, homocysteine levels, uric acid levels, coronary artery calcium [CAC] scores, carotid intima–media thickness, peripheral arterial disease, and pulse wave velocity), in addition to Framingham risk scores for predicting coronary heart disease. Only the CAC was shown to add significantly to the Framingham risk score in predicting coronary heart disease.
Read the article summary1 Walking Versus Running for Hypertension, Cholesterol, and Diabetes Mellitus Risk Reduction Arteriosclerosis, Thrombosis, and Vascular Biology, April 17, 2013
2 Renin-angiotensin system inhibitors for prevention of recurrent atrial fibrillation: a meta-analysis International Journal of Clinical Practice, April 9, 2013 Evidence Based Medicine Review Article
3
Vitamin D Levels for Preventing Acute Coronary Syndrome and Mortality: Evidence of a Non-Linear Association
Journal of Clinical Endocrinology and Metabolism, March 27, 2013
Exclusive Author Commentary
4 Coronary artery bypass graft surgery versus percutaneous coronary intervention in patients with three-vessel disease and left main coronary disease: 5-year follow-up of the randomised, clinical SYNTAX trial The Lancet, April 18, 2013
5 Advances in Stroke Prevention in Atrial Fibrillation: Enhanced Risk Stratification Combined With the Newer Oral Anticoagulants Clinical Cardiology, April 11, 2013 Free full text Review Article
6 Pulmonary hypertension: diagnosis and management British Medical Journal, April 23, 2013 Review Article
7 Oral Anticoagulation and Implantation of Cardiac Rhythm Management Devices: Is Heparin a Bridge Too Far? The Hellenic Journal of Cardiology, April 16, 2013 Free full text
8 Effect of longer term modest salt reduction on blood pressure: Cochrane systematic review and meta-analysis of randomised trials British Medical Journal, April 25, 2013 Evidence Based Medicine Review Article
9 B-Type Natriuretic Peptide and Prognosis in Heart Failure Patients With Preserved and Reduced Ejection Fraction JACC - Journal of the American College of Cardiology, April 3, 2013 Free full text
10 Iron deficiency in chronic heart failure: An international pooled analysis American Heart Journal, April 1, 2013
11 Outcomes of apixaban vs. warfarin by type and duration of atrial fibrillation: results from the ARISTOTLE trial European Heart Journal, April 22, 2013
12 Enalapril And Carvedilol for Preventing Chemotherapy-Induced Left Ventricular Systolic Dysfunction in Patients with Malignant Hemopathies. The OVERCOME Trial JACC - Journal of the American College of Cardiology, April 12, 2013
13 Primary Prevention of Cardiovascular Disease with a Mediterranean Diet New England Journal of Medicine, April 8, 2013 Free full text
14 Use and indications of cholestyramine and bile acid sequestrants Internal and Emergency Medicine, April 9, 2013 Review Article
15 Efficacy and safety of dabigatran etexilate and warfarin in real world patients with atrial fibrillation: A prospective nationwide cohort study JACC - Journal of the American College of Cardiology, April 15, 2013
16 Six-Minute Walk Test: An Effective and Necessary Tool in Modern Cardiac Rehabilitation The Hellenic Journal of Cardiology, April 16, 2013 Free full text Review Article
17 L-Carnitine in the Secondary Prevention of Cardiovascular Disease: Systematic Review and Meta-analysis Mayo Clinic Proceedings, April 19, 2013 Evidence Based Medicine Review Article
18 Role of Vitamin D in Cardiometabolic Diseases Experimental Diabetes Research, March 5, 2013 Free full text Review Article
19 Practical use of dabigatran etexilate for stroke prevention in atrial fibrillation International Journal of Clinical Practice, April 9, 2013
20 Effect of seven-day atorvastatin pretreatment on the incidence of periprocedural myocardial infarction following percutaneous coronary intervention in patients receiving long-term statin therapy. A randomized study International Journal of Cardiology, April 19, 2013
Indexed Journals in Internal Medicine: New England Journal of Medicine, The Lancet, Archives of Internal Medicine more
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